5-hydrazino-2-methoxytetrahydropyran | 137303-96-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 5-hydrazino-2-methoxytetrahydropyran
• 英文别名: (6-Methoxyoxan-3-yl)hydrazine
• CAS: 137303-96-9
• 化学式: C₆H₁₄N₂O₂
• mdl: MFCD19202527
• 分子量: 146.189
• InChiKey: FGNJSFSGSRVORR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  56.5
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5-hydrazino-2-methoxytetrahydropyran 在 sodium peroxide 、 双氧水 作用下， 以 四氢呋喃 为溶剂， 反应 72.0h， 以56%的产率得到5-hydroperoxy-2-methoxytetrahydropyran
  参考文献：
  名称：

  Perkin communications. Improved synthesis of secondary hydroperoxides from alcohols

  摘要：

  Secondary hydroperoxides have been prepared from secondary alcohols by conversion of the alcohol into its mesylate and subsequent reaction with anhydrous hydrazine followed by hydrogen peroxide and sodium peroxide.

  DOI：

  10.1039/p19910002597
• 作为产物：
  描述：

  3,4-二氢-2-甲基-吡喃 在 sodium perborate 、 硼烷 、 一水合肼 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 96.0h， 生成 5-hydrazino-2-methoxytetrahydropyran
  参考文献：
  名称：

  Perkin communications. Improved synthesis of secondary hydroperoxides from alcohols

  摘要：

  Secondary hydroperoxides have been prepared from secondary alcohols by conversion of the alcohol into its mesylate and subsequent reaction with anhydrous hydrazine followed by hydrogen peroxide and sodium peroxide.

  DOI：

  10.1039/p19910002597

文献信息

• Perkin communications. Improved synthesis of secondary hydroperoxides from alcohols
  作者：Dee Ann Casteel、Kyeong-Eun Jung

  DOI：10.1039/p19910002597

  日期：——

  Secondary hydroperoxides have been prepared from secondary alcohols by conversion of the alcohol into its mesylate and subsequent reaction with anhydrous hydrazine followed by hydrogen peroxide and sodium peroxide.