H-Gly-DL-Arg-Gly-DL-Asp-DL-Ser-DL-Pro-DL-Lys-OH

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: H-Gly-DL-Arg-Gly-DL-Asp-DL-Ser-DL-Pro-DL-Lys-OH
• 英文别名: 6-amino-2-[[1-[2-[[2-[[2-[[2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]hexanoic acid
• 化学式: C₂₈H₄₉N₁₁O₁₁
• 分子量: 715.8
• InChiKey: ZRVZOBGMZWVJOS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -10.7
• 重原子数：
  50
• 可旋转键数：
  23
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  377
• 氢给体数：
  12
• 氢受体数：
  14

文献信息

• Device and process for producing fiber products and fiber products produced thereby
  申请人：LifeNet Health

  公开号：US10905801B2

  公开（公告）日：2021-02-02

  The present invention is directed to a fiber, preferably bone fiber, having a textured surface, which acts as an effective binding substrate for bone-forming cells and for the induction or promotion of new bone growth by bone-forming cells, which bind to the fiber. Methods of using the bone fibers to induce or promote new bone growth and bone material compositions comprising the bone fibers are also described. The invention further relates to a substrate cutter device and cutter, which are effective in producing substrate fibers, such as bone fibers.

  本发明涉及一种纤维，最好是骨纤维，它具有纹理表面，可作为骨形成细胞的有效结合基质，并可诱导或促进与纤维结合的骨形成细胞的新骨生长。本发明还描述了使用骨纤维诱导或促进新骨生长的方法以及包含骨纤维的骨材料组合物。本发明还涉及一种基质切割装置和切割器，可有效生产基质纤维，如骨纤维。
• Methods and compositions for wound healing
  申请人：IMBED BIOSCIENCES, INC.

  公开号：US10940120B2

  公开（公告）日：2021-03-09

  The present invention relates to methods and compositions for wound healing. In particular, the present invention relates to promoting and enhancing wound healing by utilizing cross-linker covalent modification molecules to attach and deliver wound active agents to a wound. In addition, the present invention provides methods and compositions utilizing oppositely charged polymers to form a polyelectrolyte layer on a wound surface. The invention further relates to incorporating wound active agents into a polyelectrolyte layer for delivery to a wound.

  本发明涉及伤口愈合的方法和组合物。特别是，本发明涉及利用交联剂共价修饰分子将伤口活性剂附着和输送到伤口，从而促进和增强伤口愈合。此外，本发明还提供了利用带相反电荷的聚合物在伤口表面形成聚电解质层的方法和组合物。本发明还涉及将伤口活性剂掺入聚电解质层以输送到伤口。
• METHOD AND DEVICE FOR PROTEIN DELIVERY INTO CELLS
  申请人：CORNING INCORPORATED

  公开号：EP1525473A2

  公开（公告）日：2005-04-27
• METHOD FOR PROTEIN DELIVERY INTO CELLS
  申请人：Corning Incorporated

  公开号：EP1525473B1

  公开（公告）日：2009-03-18
• METHODS AND COMPOSITIONS FOR WOUND HEALING
  申请人：Imbed Biosciences, Inc.

  公开号：EP2262474B1

  公开（公告）日：2019-07-03