(Z)-1-benzyloxy-3-methylhex-2-ene | 833480-13-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (Z)-1-benzyloxy-3-methylhex-2-ene
• 英文别名: [(Z)-3-methylhex-2-enoxy]methylbenzene
• CAS: 833480-13-0
• 化学式: C₁₄H₂₀O
• 分子量: 204.312
• InChiKey: GFUIWMAJFODLSC-RAXLEYEMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (Z)-1-benzyloxy-3-methylhex-2-ene 在 氨 、 lithium 作用下， 反应 3.0h， 生成 (Z)-3-methylhex-2-en-1-ol
  参考文献：
  名称：

  Synthesis of alkyl (α-phenylthioalkenyl) ketones containing a (Z)-trisubstituted olefinic fragment

  摘要：

  Warren's method, which has been proposed for the synthesis of alpha-phenylthiodialkyl ketones, appeared to be inefficient for the preparation of their alkenyl alkyl analogs. The latter were prepared in good yields by alkenylation of alkyl phenylthiomethyl ketones with alkenyl bromides.

  DOI：

  10.1023/b:rucb.0000035654.60768.fb
• 作为产物：
  描述：

  戊醛叔丁基亚胺 在 sodium tetrahydroborate 、 lithium diethylamide 、 三氧化硫吡啶 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 31.5h， 生成 (Z)-1-benzyloxy-3-methylhex-2-ene
  参考文献：
  名称：

  Synthesis of alkyl (α-phenylthioalkenyl) ketones containing a (Z)-trisubstituted olefinic fragment

  摘要：

  Warren's method, which has been proposed for the synthesis of alpha-phenylthiodialkyl ketones, appeared to be inefficient for the preparation of their alkenyl alkyl analogs. The latter were prepared in good yields by alkenylation of alkyl phenylthiomethyl ketones with alkenyl bromides.

  DOI：

  10.1023/b:rucb.0000035654.60768.fb

文献信息

• Synthesis of alkyl (α-phenylthioalkenyl) ketones containing a (Z)-trisubstituted olefinic fragment
  作者：N. Ya. Grigorieva、P. G. Tsiklauri

  DOI：10.1023/b:rucb.0000035654.60768.fb

  日期：2004.3

  Warren's method, which has been proposed for the synthesis of alpha-phenylthiodialkyl ketones, appeared to be inefficient for the preparation of their alkenyl alkyl analogs. The latter were prepared in good yields by alkenylation of alkyl phenylthiomethyl ketones with alkenyl bromides.