2-Phenyldithio-aethylamin | 95056-37-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Phenyldithio-aethylamin
• 英文别名: Phenyl-(2-aminoaethyl)-disulfid；2-Phenyldithio-ethylamin；2-(Phenyldisulfanyl)ethanamine
• CAS: 95056-37-4
• 化学式: C₈H₁₁NS₂
• 分子量: 185.314
• InChiKey: WTGGJAWHQCMISE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  76.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-阿氨基乙醇酯 、 苯硫酚 在 sodium hydroxide 作用下， 以 甲醇 为溶剂， 生成 2-Phenyldithio-aethylamin
  参考文献：
  名称：

  Unsymmetrical Disulfides from an Amino Bunte Salt

  摘要：

  DOI：

  10.1021/jo01035a534

文献信息

• [EN] METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS<br/>[FR] MÉTHODES DE TRAITEMENT D'UN SUJET ET PARTICULES, POLYMÈRES ET COMPOSITIONS À CET EFFET
  申请人：FETZER OLIVER S

  公开号：WO2012044832A1

  公开（公告）日：2012-04-05

  Described herein are methods for treating a subject with combinations of polymer-agent particles and cyclodextrin polymer agent conjugates. The methods herein may be used to treat subjects identified with cancer, cardiovascular disorders, autoimmune disorders, or inflammatory disorders. Also described herein are compositions, dosage forms, and kits comprising polymer-agent particles and cyclodextrin polymer agent conjugates.

  本文描述了一种利用聚合物-药剂颗粒和环糊精聚合物药剂共轭物组合治疗受试者的方法。本文中的方法可用于治疗被诊断患有癌症、心血管疾病、自身免疫性疾病或炎症性疾病的受试者。本文还描述了包含聚合物-药剂颗粒和环糊精聚合物药剂共轭物的组合物、剂型和配套工具。
• NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES
  申请人：DRATZ Edward

  公开号：US20100252433A1

  公开（公告）日：2010-10-07

  The invention relates to compositions and methods useful in the labeling and identification of changes in protein levels, changes in enzyme activity, and changes in protein modification. The invention provides for highly soluble optical labeling molecules which are optionally cleavable after separation of mixtures of labeled proteins into components. These optical labeling molecules find utility in a variety of applications, including use in the field of proteomics.

  本发明涉及用于标记和识别蛋白质水平变化、酶活性变化和蛋白质修饰变化的组合物和方法。本发明提供了高度溶解的光学标记分子，这些分子在将标记蛋白质的混合物分离成组分后可选择性地被裂解。这些光学标记分子在各种应用中具有实用性，包括在蛋白质组学领域的应用。
• CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY
  申请人：Eliasof Scott

  公开号：US20150005230A1

  公开（公告）日：2015-01-01

  Provided are methods relating to the use of CDP-therapeutic agent conjugates for the treatment of a disease or disorder, e.g., autoimmune disease, inflammatory disease, central nervous system disorder, cardiovascular disease, or metabolic disorder. Also provided are CDP-therapeutic agent conjugates, particles comprising CDP-therapeutic agent conjugates, and compositions comprising CDP-therapeutic agent conjugates.

  提供了与使用CDP-治疗剂结合物治疗疾病或紊乱有关的方法，例如自身免疫性疾病、炎症性疾病、中枢神经系统紊乱、心血管疾病或代谢紊乱。还提供了CDP-治疗剂结合物、包含CDP-治疗剂结合物的粒子和包含CDP-治疗剂结合物的组合物。
• SYNTHESIS OF HOMOPOLYMERS AND BLOCK COPOLYMERS
  申请人：Breitenkamp Kurt

  公开号：US20120196989A1

  公开（公告）日：2012-08-02

  The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.
• METHOD FOR NUCLEIC ACID DELIVERY USING HYALURONIC ACID
  申请人：KIM Hyun-Ryoung

  公开号：US20140294752A1

  公开（公告）日：2014-10-02

  A hyaluronic acid conjugates including hyaluronic acid, a disulfide bond-containing crosslinking agent, and a cationic, amphiphilic polymer; a hyaluronic acid-nucleic acid complex in which a nucleic acid is bound to the hyaluronic acid conjugate; a composition in which the hyaluronic acid-nucleic acid complexes are crosslinked with each other; a nucleic acid delivery composition including the hyaluronic acid-nucleic acid complex; and a method of nucleic acid delivery using the hyaluronic acid-nucleic acid complex.