2-[(4-pentyloxyphenyl)amino]phenylacetic acid | 320777-99-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-[(4-pentyloxyphenyl)amino]phenylacetic acid
• 英文别名: 2-[2-(4-pentoxyanilino)phenyl]acetic acid
• CAS: 320777-99-9
• 化学式: C₁₉H₂₃NO₃
• 分子量: 313.397
• InChiKey: PADHHLXCBVBPFE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  23
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  58.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  4-戊氧基苯胺 生成 2-[(4-pentyloxyphenyl)amino]phenylacetic acid
  参考文献：
  名称：

  Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies

  摘要：

  本发明涉及抑制白蛋白非酶促糖基化的组合物，以及利用抑制白蛋白糖基化的化合物治疗糖基化相关病理的方法。

  公开号：

  US06355680B1

文献信息

• ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES
  申请人：EXOCELL, INC.

  公开号：EP1242069A2

  公开（公告）日：2002-09-25
• US6355680B1
  申请人：——

  公开号：US6355680B1

  公开（公告）日：2002-03-12
• US6552077B2
  申请人：——

  公开号：US6552077B2

  公开（公告）日：2003-04-22
• [EN] ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES<br/>[FR] COMPOSES LIANT L'ALBUMINE QUI EMPECHENT LA GLYCATION NON ENZYMATIQUE ET QUI PEUVENT ETRE UTILISES DANS LE TRAITEMENT DE PATHOLOGIES LIEES A LA GLYCATION
  申请人：EXOCELL INC

  公开号：WO2001003684A2

  公开（公告）日：2001-01-18

  The present invention is directed to compositions, comprising substituted 2(pheryl amino) pheryl acetic acid compounds, that inhibit the nonenzymatic glycation of albumin, as well as methods of using compounds that inhibit albumin glycation for the treatment of glycation-related pathologies including renol vascular dysfunction.
• Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
  申请人：Exocell, Inc.

  公开号：US06355680B1

  公开（公告）日：2002-03-12

  The present invention is directed to compositions that inhibit the nonenzymatic glycation of albumin,, as well as methods of using compounds that inhibit albumin glycation for the treatment of glycation-related pathologies.

  本发明涉及抑制白蛋白非酶促糖基化的组合物，以及利用抑制白蛋白糖基化的化合物治疗糖基化相关病理的方法。