6-Hydroxy-2-[(2-hydroxyphenyl)methylidene]-1-benzofuran-3-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 橙酮类黄酮
• 英文名称: 6-Hydroxy-2-[(2-hydroxyphenyl)methylidene]-1-benzofuran-3-one
• 化学式: C₁₅H₁₀O₄
• 分子量: 254.24
• InChiKey: WEEYRFRNWMFAKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Method of cosmetic depigmentation care by applying at least one aurone
  申请人：Perrier Eric

  公开号：US20060228313A1

  公开（公告）日：2006-10-12

  at least one aurone or a natural or synthetic derivative of aurone, or an analogue of aurone, in which the independent phenyl ring can be substituted by a heterocycle of pyrrole, imidazole, triazole, pyridine, furan, or thiophene type, is disclosed as a cosmetic agent, or as an active substance, for the manufacture either of a cosmetic composition, or of a pharmaceutical composition, notably a dermatological composition, having a melanogenesis-inhibiting activity or a depigmenting activity, or an anti-tyrosinase activity.

  本发明公开了至少一种黄酮类化合物或黄酮的天然或合成衍生物，或黄酮的类似物，其中独立的苯环可以被吡咯、咪唑、三唑、吡啶、呋喃或噻吩类的杂环取代，作为化妆品成分或活性物质，用于制备化妆品组合物或制药组合物，特别是皮肤科组合物，具有抑制黑色素生成或脱色活性或抗酪氨酸酶活性。
• A method of cosmetic depigmentation care by applying at least one aurone
  申请人：ENGELHARD LYON

  公开号：EP1709964A2

  公开（公告）日：2006-10-11

  At least one aurone or a natural or synthetic derivative of aurone, or an analogue of aurone, in which the independent phenyl ring can be substituted by a heterocycle of pyrrole, imidazole, triazole, pyridine, furan, or thiophene type, is disclosed as a cosmetic agent, or as an active substance, for the manufacture either of a cosmetic composition, or of a pharmaceutical composition, notably a dermatological composition, having a melanogenesis-inhibiting activity or a depigmenting activity, or an anti-tyrosinase activity.

  公开了至少一种脲或脲的天然或合成衍生物，或脲的类似物，其中独立的苯基环可以被吡咯、咪唑、三唑、吡啶、呋喃或噻吩类型的杂环取代，作为化妆品剂、或活性物质，用于制造具有黑色素生成抑制活性或脱色活性或抗酪氨酸酶活性的化妆品组合物或药物组合物，特别是皮肤科组合物。