N,N'-dicyclopropylbutanediamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N,N'-dicyclopropylbutanediamide
• 化学式: C₁₀H₁₆N₂O₂
• 分子量: 196.25
• InChiKey: QAIPOWFWGDUUIG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn
  申请人：Mezo R. Adam

  公开号：US20070254831A1

  公开（公告）日：2007-11-01

  The invention relates to peptides which bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used for example, in treating autoimmune diseases and inflammatory disorders. The invention also relates to methods of using and methods of making the peptides of the invention.
• IMMUNOMODULATORY PEPTIDES
  申请人：Mezo Adam R.

  公开号：US20100048488A1

  公开（公告）日：2010-02-25

  The invention relates to peptides which, in some embodiments, bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used in some embodiments, for example, in treating autoimmune diseases and inflammatory disorders. The invention also relates, in further embodiments, to methods of using and methods of making the peptides of the invention.
• US8101186B2
  申请人：——

  公开号：US8101186B2

  公开（公告）日：2012-01-24