[3-(2-methyl-1,3-dioxolan-2-yl)phenyl]diphenylphosphine | 50777-94-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [3-(2-methyl-1,3-dioxolan-2-yl)phenyl]diphenylphosphine
• 英文别名: [3-(2-methyl-1,3-dioxolan-2-yl)phenyl]diphenylphosphane；[3-(2-Methyl-1,3-dioxolane-2-yl)phenyl]diphenylphosphane；[3-(2-methyl-1,3-dioxolan-2-yl)phenyl]-diphenylphosphane
• CAS: 50777-94-1
• 化学式: C₂₂H₂₁O₂P
• 分子量: 348.381
• InChiKey: UQLAADFVCZRPBA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  [3-(2-methyl-1,3-dioxolan-2-yl)phenyl]diphenylphosphine 在 对甲苯磺酸 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 2.0h， 生成 [3-(3-dimethylamino-1-oxoprop-2-en-yl)phenyl]diphenylphosphine
  参考文献：
  名称：

  Novel phosphine ligands bearing 3(5)-pyrazolyl and 4-(2-amino)pyrimidinyl groups: Synthesis and coordination chemistry

  摘要：

  Novel triphenyl phosphine ligands bearing pyrazole or 2-aminopyrimidine groups in the ortho or meta position of one or three of the phenyl rings were obtained starting from the corresponding acyl derivatives Ph2P(o-C6H4-COCH3), Ph2P(m-C6H4-COCH3), Or P(m-C6H4-COCH3)(3)- Conversion of the acyl groups into 3-dimethylamino-2-propen-l-onyl units was achieved by reaction with HC(O-Me)(2)NMe2 which underwent ring closing with hydrazine or guanidine to yield the desired heterocycles. Two palladium complexes were synthesized using the coordinatively labile precursor (PhCN)(2)PdCl2, one of them could be characterized by X-ray structure analysis. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2005.08.032
• 作为产物：
  描述：

  3'-溴苯乙酮 在 对甲苯磺酸 、 magnesium 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 2.0h， 生成 [3-(2-methyl-1,3-dioxolan-2-yl)phenyl]diphenylphosphine
  参考文献：
  名称：

  Novel phosphine ligands bearing 3(5)-pyrazolyl and 4-(2-amino)pyrimidinyl groups: Synthesis and coordination chemistry

  摘要：

  Novel triphenyl phosphine ligands bearing pyrazole or 2-aminopyrimidine groups in the ortho or meta position of one or three of the phenyl rings were obtained starting from the corresponding acyl derivatives Ph2P(o-C6H4-COCH3), Ph2P(m-C6H4-COCH3), Or P(m-C6H4-COCH3)(3)- Conversion of the acyl groups into 3-dimethylamino-2-propen-l-onyl units was achieved by reaction with HC(O-Me)(2)NMe2 which underwent ring closing with hydrazine or guanidine to yield the desired heterocycles. Two palladium complexes were synthesized using the coordinatively labile precursor (PhCN)(2)PdCl2, one of them could be characterized by X-ray structure analysis. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2005.08.032

文献信息

• Method for the Manufacture of Substituted Phosphanes, and Substituted Phosphanes Manufactured According to Said Method
  申请人：Thiel Werner

  公开号：US20080221335A1

  公开（公告）日：2008-09-11

  The invention relates to a method for the manufacture of substituted phosphanes and substituted phosphanes manufactured according to the method. Phosphanes, phosphane oxides, sulfides or selenides are used as ligands in coordination compounds. They play a central role in controlling the activity and selectivity of catalysts. The object is achieved by the invention by synthesizing heterocyclic substituents on aromatic groups by introducing acetyl groups. In this manner, previously unknown representatives of the families of phosphanes, phosphane oxides, sulfides and selenides are made accessible.

  本发明涉及一种制造取代膦和按照该方法制造的取代膦的方法。在配位化合物中，膦、膦氧化物、硫化物或硒化物被用作配体。它们在控制催化剂的活性和选择性方面起着核心作用。本发明通过在芳香族基团上引入乙酰基合成杂环取代基，从而实现了该目标。通过这种方法，膦、膦氧化物、硫化物和硒化物的新的未知代表得以获得。
• Method for the manufacture of substituted phosphanes, and substituted phosphanes manufactured according to said method
  申请人：Zylum Beteiligungsgesellschaft mbH & Co. Patent II KG

  公开号：US07910744B2

  公开（公告）日：2011-03-22

  The invention relates to a method for the manufacture of substituted phosphanes and substituted phosphanes manufactured according to the method. Phosphanes, phosphane oxides, sulfides or selenides are used as ligands in coordination compounds. They play a central role in controlling the activity and selectivity of catalysts. The object is achieved by the invention by synthesizing heterocyclic substituents on aromatic groups by introducing acetyl groups. In this manner, previously unknown representatives of the families of phosphanes, phosphane oxides, sulfides and selenides are made accessible.

  本发明涉及一种制备取代膦和按照该方法制备的取代膦的方法。膦、膦氧化物、硫化物或硒化物被用作配位化合物中的配体。它们在控制催化剂的活性和选择性方面起着核心作用。本发明通过在芳香族基团上引入乙酰基合成杂环取代基，从而实现了该目标。以这种方式，先前未知的膦、膦氧化物、硫化物和硒化物家族的代表变得可获得。
• WO2006/45272
  申请人：——

  公开号：——

  公开（公告）日：——
• VERFAHREN ZUR HERSTELLUNG SUBSTITUIERTER PHOSPHANE UND NACH DEM VERFAHREN HERGESTELLTE SUBSTITUIERTE PHOSPHANE
  申请人：Technische Universität Chemnitz

  公开号：EP1805193A1

  公开（公告）日：2007-07-11
• VERFAHREN ZUR HERSTELLUNG SUBSTITUIERTER PHOSPHANE
  申请人：Zylum Beteiligungsgesellschaft mbH & Co. Patente II KG

  公开号：EP1805193B1

  公开（公告）日：2010-12-29