4,8-Dimethyldodecansaeure | 53696-16-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4,8-Dimethyldodecansaeure
• 英文别名: 4,8-Dimethyl-dodecanoic acid；4,8-dimethyldodecanoic acid
• CAS: 53696-16-5
• 化学式: C₁₄H₂₈O₂
• 分子量: 228.375
• InChiKey: JJPHRFRFAKPCKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  16
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Pharmaceutical magnetic nano-particle composition
  申请人：UNIVERSITÄTSKLINIKUM ERLANGEN

  公开号：EP2508171A1

  公开（公告）日：2012-10-10

  The invention relates to a pharmaceutical composition comprising magnetic nano-particles for magnetic targeting of drugs and imaging agents. The invention further relates to the use of said pharmaceutical composition as a drug carrier, for use as an imaging agent, for use as a medicament and specifically for use in cancer treatment by magnetic drug targeting using an external magnetic field. The present invention also relates to a method for manufacturing said pharmaceutical composition and a method for guiding and accumulating said pharmaceutical composition to a target tissue contained in a subject.

  本发明涉及一种药物组合物，其中包含用于药物和成像剂磁性靶向的磁性纳米颗粒。本发明还涉及将所述药物组合物用作药物载体、用作成像剂、用作药物，特别是用于利用外部磁场进行磁性药物靶向治疗癌症。本发明还涉及一种制造所述药物组合物的方法，以及一种将所述药物组合物引导和积聚到受试者所含靶组织的方法。
• [EN] BIOMARKERS OF REDUCED INSULIN ACTION<br/>[FR] MARQUEURS BIOLOGIQUES D'UNE ACTION RÉDUITE DE L'INSULINE
  申请人：MAYO FOUNDATION

  公开号：WO2012058298A1

  公开（公告）日：2012-05-03

  This document provides methods and materials for assessing metabolic disorders related to reduced insulin action (e.g. insulin resistance or insulin deficiency) in a mammal (e.g. human). For example, methods and materials for assessing insulin resistance, risk of developing insulin resistance and monitoring efficacy of insulin resistance treatment are provided.