(4E,7E,10E,13E)-hexadeca-4,7,10,13-tetraenoic acid | 3209-28-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (4E,7E,10E,13E)-hexadeca-4,7,10,13-tetraenoic acid
• CAS: 3209-28-7
• 化学式: C₁₆H₂₄O₂
• 分子量: 248.36
• InChiKey: IVTCJQZAGWTMBZ-GFRMADBLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  18
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (4E,7E,10E,13E)-hexadeca-4,7,10,13-tetraenoic acid 、 甲醇 生成 methyl (4E,7E,10E,13E)-hexadeca-4,7,10,13-tetraenoate
  参考文献：
  名称：

  REZANKA, T., LC AND GC , 8,(1990) N, C. 542, 544-545

  摘要：

  DOI：

文献信息

• 細胞活性化物質を含有する海藻抽出物およびその製造方法
  申请人：——

  公开号：JP2005023028A

  公开（公告）日：2005-01-27

  【課題】免疫増強剤有効成分、化粧品素材成分、健康食品成分、食品添加物として用いられ、簡便に大量な製造が可能でかつ安全な、海洋資源由来の細胞活性化物質含有海藻抽出物を提供する。【解決手段】海藻抽出物は、海藻の脂質成分であり、細胞活性化物質を含有している。細胞活性化物質は、好酸球活性化物質であることが好ましい。好酸球活性化物質は、４，７，１０，１３−ヘキサデカテトラエン酸、６，９，１２，１５−オクタデカテトラエン酸、５，８，１１，１４，１７−エイコサペンタエン酸、９，１２，１５−オクタデカトリエン酸、およびそれらの類縁体の少なくともいずれかのｎ−３系不飽和脂肪酸類である。【選択図】 なし。

  海藻提取物可用作免疫刺激剂活性成分、化妆品原料成分、保健食品成分和食品添加剂，易于大量生产，安全性高，且提取自海洋资源。海藻提取物是海藻的脂质成分，含有细胞活化物质。细胞活化物质最好是嗜酸性粒细胞活化物质。嗜酸性粒细胞活化物质包括 4,7,10,13- 十六碳四烯酸、6,9,12,15- 十八碳四烯酸、5,8,11,14,17-二十碳五烯酸、9,12,15-十八碳三烯酸及其至少一种类似物，均为 n-3 不饱和脂肪酸。无。
• OMEGA-3 FATTY ACID COMPOSITION FOR PREVENTING AND/OR TREATING CACHEXIA
  申请人：BASF AS

  公开号：EP3558292A1

  公开（公告）日：2019-10-30
• Omega-3 Fatty Acid Composition for Preventing and/or Treating Cachexia
  申请人：BASF AS

  公开号：US20200085774A1

  公开（公告）日：2020-03-19

  Compositions of a polyunsaturated omega-3 fatty acid such as (5Z,8Z,11Z,14Z,17Z)-eicosa-5,8,11,14,17-pentaenoic acid (EPA) and (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid (DHA) for preventing and/or treating cachexia in a subject are disclosed. The compositions contain a certain amount of the fatty acids as monoacylglycerides. Further, a method of preventing and/or treating cachexia in a subject is disclosed, including administering a composition of EPA and DHA to the subject, wherein at least a part of the fatty acids are provided in monoacylglyceride form.
• [EN] OMEGA-3 FATTY ACID COMPOSITION FOR PREVENTING AND/OR TREATING CACHEXIA<br/>[FR] COMPOSITION D'ACIDES GRAS OMÉGA-3 POUR PRÉVENIR ET/OU TRAITER LA CACHEXIE
  申请人：PRONOVA BIOPHARMA NORGE AS

  公开号：WO2018115459A1

  公开（公告）日：2018-06-28

  The present invention relates to compositions of polyunsaturated omega-3 fatty such as of (5Z,8Z,11Z,14Z,17Z)-eicosa-5,8,11,14,17-pentaenoicacid (EPA) and (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoicacid (DHA) for preventing and/or treating cachexia in a subject. Particularly, the compositions comprise a certain amount of the fatty acids as monoacylglycerides. Further, the compositions of omega-3 fatty acids preferably comprise a certain ratio of the fatty acids as mono-, di- and triacylglycerides as this enhances the digestion and uptake of the EPA and DHA fatty acids. Further, the invention relates to a method of preventing and/or treating cachexia in a subject, including administering a composition of EPA and DHA to the subject, wherein at least a part of the fatty acids are provided in monoacylglyceride form.
• [EN] LIPOXYGENASE-CATALYZED PRODUCTION OF UNSATURATED C10-ALDEHYDES FROM POLYUNSATURATED FATTY ACIDS (PUFA)<br/>[FR] PRODUCTION CATALYSÉE PAR LIPOXYGÉNASE D'ALDÉHYDES EN C10 INSATURÉS À PARTIR D'ACIDES GRAS POLYINSATURÉS (AGPI)
  申请人：FIRMENICH & CIE

  公开号：WO2020079223A1

  公开（公告）日：2020-04-23

  The present invention provides novel methods for the lipoxygenase (LOX)-catalyzed production of aliphatic unsaturated C10- aldehyde compounds from polyunsaturated fatty acid (PUFA) sources. The present invention also relates to the isolation and characterization of novel, preferably bifunctional LOXs from different algae sources and the identification of structurally and/or functionally related LOXs from different bacterial sources. The present invention also relates to the provision of enzyme mutants derived from said newly identified enzymes. A further aspect of the present invention relates to corresponding coding sequences of said enzymes, recombinant vectors, and recombinant host cells suitable for the production of such LOXs and for performing the novel production methods of aliphatic unsaturated C10- aldehyde compounds. Another aspect of the invention relates to the use of particular aldehydes or aldehyde mixtures, as obtained according to the present invention as flavor ingredient or ingredient for food or feed compositions.