N-benzyl-3,4-dimethylsuccinimide | 42856-52-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-benzyl-3,4-dimethylsuccinimide
• 英文别名: 1-benzyl-3,4-dimethyl-2,5-pyrrolidinedione；1-Benzyl-3,4-dimethyl-pyrrolidine-2,5-dione；1-benzyl-3,4-dimethylpyrrolidine-2,5-dione
• CAS: 42856-52-0
• 化学式: C₁₃H₁₅NO₂
• 分子量: 217.268
• InChiKey: DYFWRDJHUDMNDH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-benzyl-3,4-dimethylsuccinimide 在 对甲苯磺酸 作用下， 生成 1,5-Dihydro-1-benzyl-3,4-dimethyl-2H-pyrrol-2-one
  参考文献：
  名称：

  Reduction of Five-Membered .ALPHA.,.BETA.-Unsaturated Lactones and Related Compounds with the Ni2+/BH4- System.

  摘要：

  α, β-不饱和乳酮（5）和乳酰胺（7）在Ni2+/BH-4系统的还原反应中，生成了高立体选择性的顺式氢化产物（8a和9a）。顺式产物（8a和9a）通过在无水甲醇中与甲醇钠回流，易于异构化为相应的反式异构体（8b和9b）。以肉桂酸甲酯为底物的同位素标记研究表明，该还原反应通过一个碳-镍中间体以逐步方式进行。

  DOI：

  10.1248/cpb.39.1167
• 作为产物：
  描述：

  N-benzyl-3,4-dimethylmaleimide 在 sodium tetrahydroborate 、 nickel dichloride 作用下， 以 甲醇 为溶剂， 以97.7%的产率得到N-benzyl-3,4-dimethylsuccinimide
  参考文献：
  名称：

  Reduction of Five-Membered .ALPHA.,.BETA.-Unsaturated Lactones and Related Compounds with the Ni2+/BH4- System.

  摘要：

  α, β-不饱和乳酮（5）和乳酰胺（7）在Ni2+/BH-4系统的还原反应中，生成了高立体选择性的顺式氢化产物（8a和9a）。顺式产物（8a和9a）通过在无水甲醇中与甲醇钠回流，易于异构化为相应的反式异构体（8b和9b）。以肉桂酸甲酯为底物的同位素标记研究表明，该还原反应通过一个碳-镍中间体以逐步方式进行。

  DOI：

  10.1248/cpb.39.1167

文献信息

• Asymmetric desymmetrization of meso-pyrrolidine derivatives by enantiotopic selective CH hydroxylation using (salen)manganese(III) complexes
  作者：T. Punniyamurthy、Tsutomu Katsuki

  DOI：10.1016/s0040-4020(99)00518-9

  日期：1999.7

  Chiral (salen)manganese(III) complexes 1 catalyzed the asymmetric desymmetrization of N-protectedmeso-pyrrolidine derivatives 3, 6–8, 15 and 18 by enantiotopic selective C-H oxidation in the presence of terminal oxidant iodosylbenzene. The oxidation occurred chemoselectively at the carbon α to the nitrogen atom to afford optically active hydroxypyrrolidine derivatives 9, 11, 13, 16, 19 and 21 that

  手性（沙仑）锰（III）络合物1催化的不对称desymmetrization Ñ -保护的内消旋-吡咯烷衍生物3，6-8，15和18通过在终端氧化剂亚碘酰苯的存在下对映选择性氧化CH。氧化在碳原子上对氮原子进行化学选择，得到旋光的羟基吡咯烷衍生物9、11、13、16、19和21，它们用Jones试剂进一步氧化为手性内酰胺。内消旋吡咯烷衍生物的N-保护基对对映选择性具有显著作用。
• Composition, Retardation Plate, Liquid-Crystal Display Device, and Method for Producing Retardation Plate
  申请人：Li Yi

  公开号：US20090174844A1

  公开（公告）日：2009-07-09

  A composition comprising at least one liquid-crystal compound and a polymer having at least one group of the following formula: wherein Mp represents a trivalent linking group; L represents a single bond, or a divalent linking group; X represents a substituted or unsubstituted cyclic linking group; Y represents a single bond, or a divalent linking group; Z represents a substituted or unsubstituted cyclic group; n is 1 to 10.

  一种组合物，包括至少一种液晶化合物和至少一种聚合物，该聚合物具有以下公式中的至少一种基团：其中Mp代表三价连接基团；L代表单键或双价连接基团；X代表取代或未取代的环状连接基团；Y代表单键或双价连接基团；Z代表取代或未取代的环状基团；n为1至10。
• Composition, retardation plate, and liquid-crystal display device
  申请人：Li Yi

  公开号：US20080090027A1

  公开（公告）日：2008-04-17

  A composition comprising at least one liquid-crystal compound and a polymer having at least one group of the following formula (A) as the constitutive unit thereof: wherein Mp represents a trivalent linking group; L represents a single bond, or a bivalent linking group; X represents a substituted or unsubstituted functional group having a cyclic structure.
• LIQUID CRYSTAL COMPOSITION, RETARDATION PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND PROCESS FOR PRODUCING RETARDATION PLATE
  申请人：LI Yi

  公开号：US20100078592A1

  公开（公告）日：2010-04-01

  A composition comprising at least one liquid crystal compound, and at least one polymer is disclosed. The polymer comprises a constitutional unit represented by a following formula (A) and a constitutional unit derived from a monomer having a fluoroaliphatic group(s): wherein Mp represents a trivalent group constituting fully or partially a polymer main chain; L represents a single bond or a divalent linking group; and X represents a substituted or non-substituted aromatic condensed ring group.
• PHOTOSENSITIVE RESIN COMPOSITION FOR MICROLENS
  申请人：Kishioka Takahiro

  公开号：US20120156598A1

  公开（公告）日：2012-06-21

  There is provided a photosensitive resin composition for a microlens. A photosensitive resin composition for a microlens, comprising a component (A), a component (B) and a component (C), wherein the component (A) is a polymer having a maleimide structural unit of Formula (1), the component (B) is a cross-linking agent, and the component (C) is a photosensitizing agent.