7Z-nonadecenoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 7Z-nonadecenoic acid
• 英文别名: (Z)-nonadec-7-enoic acid
• 化学式: C₁₉H₃₆O₂
• 分子量: 296.5
• InChiKey: MBSJMRUSWQBXNI-SEYXRHQNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  21
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Method for producing polyunsaturated fatty acids
  申请人：Cirpus Petra

  公开号：US10190131B2

  公开（公告）日：2019-01-29

  The invention relates to a method for producing eicosapentanoic acid, docosapentanoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypeptide with a Δ6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity, the nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a Δ4 desaturase activity is also introduced into the plant.

  本发明涉及一种在转基因植物中生产二十碳戊酸、二十二碳戊酸和/或二十二己酸的方法。根据上述方法，植物含有至少一种编码具有 Δ6 去饱和酶活性的多肽的核酸序列、至少一种编码具有 Δ6 伸长酶活性的多肽的核酸序列、至少一种编码具有 Δ5 去饱和酶活性的多肽的核酸序列、和至少一个编码具有Δ5延伸酶活性的多肽的核酸序列，编码具有Δ5延伸酶活性的多肽的核酸序列相对于该序列来源生物体内的核酸序列进行了修改，使其适应至少一种植物的密码子使用。为了生产二十二碳己酸，还将至少一种编码具有Δ4去饱和酶活性的多肽的核酸序列引入植物中。
• Oils, lipids and fatty acids produced in transgenic Brassica plant
  申请人：BASF Plant Science GmbH

  公开号：US10301638B2

  公开（公告）日：2019-05-28

  The invention relates to a method for producing eicosapentaenoic acid, docosapentaenoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypeptide with a Δ6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity, the nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a Δ4 desaturase activity is also introduced into the plant.

  本发明涉及一种在转基因植物中生产二十碳五烯酸、二十二碳五烯酸和/或二十二己酸的方法。根据上述方法，植物含有至少一种编码具有 Δ6 去饱和酶活性的多肽的核酸序列、至少一种编码具有 Δ6 伸长酶活性的多肽的核酸序列、至少一种编码具有 Δ5 去饱和酶活性的多肽的核酸序列、和至少一个编码具有Δ5延伸酶活性的多肽的核酸序列，编码具有Δ5延伸酶活性的多肽的核酸序列相对于该序列来源生物体内的核酸序列进行了修改，使其适应至少一种植物的密码子使用。为了生产二十二碳己酸，还将至少一种编码具有Δ4去饱和酶活性的多肽的核酸序列引入植物中。
• Method For Producing Polyunsaturated Fatty Acids
  申请人：Cirpus Petra

  公开号：US20100227924A1

  公开（公告）日：2010-09-09

  The invention relates to a method for producing eicosapentanoic acid, docosapentanoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypeptide with a Δ6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity, the nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a Δ4 desaturase activity is also introduced into the plant.
• METHOD FOR PRODUCING POLYUNSATURATED FATTY ACIDS
  申请人：BASF Plant Science GmbH

  公开号：US20160369290A1

  公开（公告）日：2016-12-22

  The invention relates to a method for producing eicosapentanoic acid, docosapentanoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypetide with a Δ6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity, the nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a Δ4 desaturase activity is also introduced into the plant.
• OILS, LIPIDS AND FATTY ACIDS PRODUCED IN TRANSGENIC BRASSICA PLANT
  申请人：BASF Plant Science GmbH

  公开号：US20190218568A1

  公开（公告）日：2019-07-18

  The invention relates to a method for producing eicosapentanoic acid, docosapentanoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypetide with a Δ6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity, the nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a Δ4 desaturase activity is also introduced into the plant.