10-Methylene-octadecanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 10-Methylene-octadecanoic acid
• 英文别名: 10-methylideneoctadecanoic acid
• 化学式: C₁₉H₃₆O₂
• 分子量: 296.5
• InChiKey: WLVDYCRJAOTRPO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  21
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• Irreversible heat-sensitive composition
  申请人：Nichiyu Giken Kogyo Co., Ltd.

  公开号：EP1149880A1

  公开（公告）日：2001-10-31

  An irreversible heat-sensitive composition comprises a mixture of a granular or powdery heat-fusible substance having a melting point corresponding to a temperature to be recorded and a granular or powdery dyestuff diffusible into the fused heat-fusible substance through dispersion or dissolution. A heat-sensitive ink comprises the irreversible heat-sensitive composition and an ink vehicle capable of diffusing the fused heat-fusible substance therein. A heat-sensitive ink according to another embodiment comprises microcapsules, which encapsulate the irreversible heat-sensitive composition. A heat-sensitive indicator comprises a substrate provided thereon with a printed heat-sensitive ink, the heat-sensitive ink being one of these heat-sensitive inks.

  不可逆热敏组合物包括熔点与待记录温度相对应的颗粒状或粉状热敏物质与可通过分散或溶解扩散到熔融热敏物质中的颗粒状或粉状染料的混合物。热敏油墨包括不可逆热敏组合物和能够将熔融热敏物质扩散到其中的油墨载体。根据另一个实施方案，热敏油墨包括封装不可逆热敏组合物的微胶囊。热敏指示器包括一个基板，基板上印有热敏油墨，热敏油墨是这些热敏油墨中的一种。
• Heterologous production of 10-methylstearic acid
  申请人：Novogy, Inc.

  公开号：US10457963B2

  公开（公告）日：2019-10-29

  Nucleic acids and cells comprising a methyltransferase gene and/or a reductase gene are disclosed. These nucleic acids and cells may be used to produce branched (methyl)lipids, such as 10-methylstearate.

  本研究公开了含有甲基转移酶基因和/或还原酶基因的核酸和细胞。这些核酸和细胞可用于生产支链（甲基）脂类，如 10-甲基硬脂酸酯。
• Heterologous production of 10-methylstearic acid by cells expressing recombinant methyltransferase
  申请人：Ginkgo Bioworks, Inc.

  公开号：US11236373B2

  公开（公告）日：2022-02-01

  Disclosed herein are cells, nucleic acids, and proteins that can be used to produce branched (methyl)lipids, such as 10-methylstearic acids, and compositions that include such lipids. Cells disclosed herein comprise methyltransferase and/or reductase genes from bacteria of the class Gammaproteobacteria, which encode enzymes capable of catalyzing the production of branched (methyl)lipids from unbranched, unsaturated lipids. Saturated branched (methyl)lipids produced using embodiments of the present invention have favorable low-temperature fluidity and favorable oxidative stability, which are desirable properties for lubricants and specialty fluids.

  本文公开了可用于生产支链（甲基）脂类（如 10-甲基硬脂酸）的细胞、核酸和蛋白质，以及包括这种脂类的组合物。本文公开的细胞包含来自伽马蛋白菌类细菌的甲基转移酶和/或还原酶基因，这些基因编码的酶能够催化未支链的不饱和脂类生产支链（甲基）脂类。利用本发明实施例生产的饱和支链（甲基）脂具有良好的低温流动性和氧化稳定性，这些特性是润滑剂和特种液体所需要的。