6E,10E-octadecadienoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6E,10E-octadecadienoic acid
• 英文别名: (6E,10E)-octadeca-6,10-dienoic acid
• 化学式: C₁₈H₃₂O₂
• 分子量: 280.4
• InChiKey: VHWOFKOZZDNTLJ-AFAJWACHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  20
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Conjugated fatty acids and related compounds
  申请人：Natural ASA

  公开号：US20010023259A1

  公开（公告）日：2001-09-20

  It has been demonstrated that conjugated linoleic acid isomers with the first double bond in position 9 (cis) or 10 (trans), added exogenously, can be desaturated in position 6 by the cyanobacterium Spirulina platensis . The metabolites, 6-cis, 9-cis, 11-trans-octadecatrienoic and 6-cis,10-trans,12-cis-octadecatrienoic acids, which have not previously been characterized, were isolated by a combination of chromatographic techniques and the structures were confirmed by gas chromatography-mass spectrometry in the form of picolinyl ester and dimethyloxazoline derivatives.

  研究表明，外源添加的共轭亚油酸异构体的第一个双键位于第 9 位（顺式）或第 10 位（反式），可以通过蓝藻的作用使第 6 位脱饱和 蓝藻 .这些代谢物，即 6-顺式、9-顺式、11-反式-十八碳三烯酸和 6-顺式、10-反式、12-顺式-十八碳三烯酸，以前从未被表征过，它们通过色谱技术的组合被分离出来，并以吡啶酯和二甲基噁唑啉衍生物的形式通过气相色谱-质谱法确认了其结构。
• CONJUGATED FATTY ACIDS AND RELATED COMPOUNDS, AND METHOD FOR THEIR ENZYMATIC PREPARATION
  申请人：Natural ASA

  公开号：EP1246932A1

  公开（公告）日：2002-10-09
• [EN] CONJUGATED FATTY ACIDS AND RELATED COMPOUNDS, AND METHOD FOR THEIR ENZYMATIC PREPARATION<br/>[FR] CONJUGAISON D'ACIDES GRAS ET COMPOSES ASSOCIES
  申请人：NATURAL ASA

  公开号：WO2001044485A1

  公开（公告）日：2001-06-21

  It has been demonstrated that conjugated linoleic acid isomers with the first double bond in position 9 (cis) or 10 (trans), added exogenously, can be desaturated in position 6 by the cyanobacterium Spirulina platensis. The metabolites, 6-cis, 9-cis, 11-trans-octadecatrienoic and 6-cis, 10-trans, 12-cis-octadecatrienoic acids, which have not previously been characterized, were isolated by a combination of chromatographic techniques and the structures were confirmed by gas chromatography-mass spectrometry in the form of picolinyl ester and dimethyloxazoline derivatives.