(2Z)-2-benzylidene-4,5,6-trihydroxy-1-benzofuran-3-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 橙酮类黄酮
• 英文名称: (2Z)-2-benzylidene-4,5,6-trihydroxy-1-benzofuran-3-one
• 化学式: C₁₅H₁₀O₅
• 分子量: 270.24
• InChiKey: DYDUQRQYDQHKJU-WDZFZDKYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• AURONES AS SELECTIVE PDE INHIBITORS AND THEIR USE IN NEUROLOGICAL CONDITIONS AND DISORDERS
  申请人：D/O V.K. George Annie George

  公开号：US20100267823A1

  公开（公告）日：2010-10-21

  The invention relates to aurones and extracts comprising them useful in the prophylactic and/or therapeutic treatment of an animal (including a human) with a phosphodiesterase (PDE) dependent disease or condition of the central nervous system, as well as methods, uses and other inventions related thereto.
• AURONES AS ESTROGEN RECEPTOR MODULATORS AND THEIR USE IN SEX HORMONE DEPENDENT DISEASES
  申请人：George Annie George D/O V.K.

  公开号：US20100267822A1

  公开（公告）日：2010-10-21

  The invention relates to aurones and extracts comprising them useful in the prophylactic and/or therapeutic treatment of an animal (including a human) with an estrogen receptor (ER) related disease or condition of the animal or human body, as well as methods, uses and other inventions related thereto.