(3R)-Methylcarbamoyl-7-sulfoamino-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (3R)-Methylcarbamoyl-7-sulfoamino-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester
• 英文别名: [(3S)-3-(methylcarbamoyl)-2-phenylmethoxycarbonyl-3,4-dihydro-1H-isoquinolin-7-yl]sulfamic acid
• 化学式: C₁₉H₂₁N₃O₆S
• 分子量: 419.5
• InChiKey: MFDBNNQUDZFSES-KRWDZBQOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  133
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Tetrahydroisoquinolnyl sulfamic acids
  申请人：Klopfenstein Rees Sean

  公开号：US20050154011A1

  公开（公告）日：2005-07-14

  Compounds of formula (I): are effective in the treatment of protein tyrosine phosphatase (PTPase) mediated disorder such as diabetes.

  公式（I）的化合物在治疗蛋白酪氨酸磷酸酶（PTPase）介导的疾病，如糖尿病方面具有有效性。
• Laundry and cleaning compositions
  申请人：Bettiol Philippe Jean-Luc

  公开号：US20050009727A1

  公开（公告）日：2005-01-13

  The present invention relates to a laundry and cleaning composition comprising a detersive ingredient and a product of reaction between a primary and/or secondary amine and a perfume component. By the present invention, there is obtained a release of the active component over a longer period of time than by the use of the active itself.

  本发明涉及一种洗衣和清洁组合物，该组合物包含一种去污成分和一种伯胺和/或仲胺与香水成分的反应产物。与使用活性成分本身相比，本发明可在更长的时间内释放活性成分。
• [EN] TETRAHYDROISOQUINOLINYL SULFAMIC ACIDS<br/>[FR] ACIDES SULFAMIQUES DE TETRAHYDROISOQUINOLINYLE
  申请人：PROCTER & GAMBLE

  公开号：WO2004074256A1

  公开（公告）日：2004-09-02

  Compounds of formula (I): (I)are effective in the treatment of protein tyrosine phosphatase (PTPase) mediated disorder such as diabetes.