Methyl eicosa-7,10,13-trienoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Methyl eicosa-7,10,13-trienoate
• 英文别名: methyl (7E,10E,13E)-icosa-7,10,13-trienoate
• 化学式: C₂₁H₃₆O₂
• 分子量: 320.5
• InChiKey: VJNPJEDIROCCHU-NCEJYBGESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  23
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Genes participating in the synthesis of fatty acid having trans-11-,cis-13-conjugated double bond and utilization thereof
  申请人：Osumi Mari

  公开号：US20050108788A1

  公开（公告）日：2005-05-19

  An object of the present invention is to clone a gene which is involved in synthesis of fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bone at position Δ12. The present invention provides a gene having any one of the following nucleotide sequences: (A) a nucleotide sequence encoding an amino acid sequence shown in SEQ ID NO: 1 or 12; (B) a nucleotide sequence encoding an amino acid sequence comprising a deletion, addition or substitution of one or several amino acids with respect to the amino acid sequence shown in SEQ NO: 1 or 12, and having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12; (C) a nucleotide sequence shown in SEQ ID NO: 2 or 13; (D) a nucleotide sequence comprising a deletion, addition or substitution of one or several nucleotides with respect to the nucleotide sequence shown in SEQ ID NO: 2 or 13, and encoding a protein having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12; and (E) a nucleotide sequence hybridizing with the nucleotide sequence shown in SEQ ID NO: 2 or 13 or a complementary sequence thereof under stringent conditions, and encoding a protein having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12.

  本发明的目的是克隆参与合成具有位置Δ12处双键的脂肪酸中具有反11-顺13-共轭双键的基因。本发明提供了具有以下任一核苷酸序列的基因：(A)编码SEQ ID NO:1或12中所示氨基酸序列的核苷酸序列；(B)编码与SEQ NO:1或12中所示氨基酸序列相比具有一个或多个氨基酸的缺失、添加或置换，并具有从位置Δ12处具有双键的脂肪酸合成反11-顺13-共轭双键的能力的氨基酸序列的核苷酸序列；(C) SEQ ID NO:2或13所示的核苷酸序列；(D)与SEQ ID NO:2或13所示的核苷酸序列相比具有一个或多个核苷酸的缺失、添加或置换，并编码具有从位置Δ12处具有双键的脂肪酸合成反11-顺13-共轭双键的能力的蛋白质的核苷酸序列；以及(E)在严格条件下与SEQ ID NO:2或13所示的核苷酸序列或其互补序列杂交，并编码具有从位置Δ12处具有双键的脂肪酸合成反11-顺13-共轭双键的能力的蛋白质的核苷酸序列。
• GENES PARTICIPATING IN THE SYNTHESIS OF FATTY ACID HAVING TRANS-11-,CIS-13- CONDJUGATED DOUBLE BOND AND UTILIZATION THEREOF
  申请人：Plantech Research Institute

  公开号：EP1437412A1

  公开（公告）日：2004-07-14

  An object of the present invention is to clone a gene which is involved in synthesis of fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bone at position Δ12. The present invention provides a gene having any one of the following nucleotide sequences: (A) a nucleotide sequence encoding an amino acid sequence shown in SEQ ID NO: 1 or 12; (B) a nucleotide sequence encoding an amino acid sequence comprising a deletion, addition or substitution of one or several amino acids with respect to the amino acid sequence shown in SEQ NO: 1 or 12, and having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12; (C) a nucleotide sequence shown in SEQ ID NO: 2 or 13; (D) a nucleotide sequence comprising a deletion, addition or substitution of one or several nucleotides with respect to the nucleotide sequence shown in SEQ ID NO: 2 or 13, and encoding a protein having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12; and (E) a nucleotide sequence hybridizing with the nucleotide sequence shown in SEQ ID NO: 2 or 13 or a complementary sequence thereof under stringent conditions, and encoding a protein having an ability of synthesizing fatty acid having trans-11-, cis-13-conjugated double bonds from fatty acid having a double bond at position Δ12.

  本发明的目的是克隆一种基因，该基因参与从在Δ12位有双键的脂肪酸合成具有反式-11-、顺式-13-共轭双键的脂肪酸。本发明提供了一种具有下列任何一种核苷酸序列的基因： (A) 编码 SEQ ID NO: 1 或 12 所示氨基酸序列的核苷酸序列； (B)编码氨基酸序列的核苷酸序列，该氨基酸序列包括相对于SEQ NO：1或12所示氨基酸序列的一个或几个氨基酸的缺失、添加或取代，并且具有从在Δ12位具有双键的脂肪酸合成具有反式-11-、顺式-13-共轭双键的脂肪酸的能力； (C) SEQ ID NO: 2 或 13 中所示的核苷酸序列； (D) 包含相对于 SEQ ID NO: 2 或 13 所示核苷酸序列的一个或多个核苷酸的缺失、添加或替换的核苷酸序列，该核苷酸序列编码一种蛋白质，该蛋白质具有从在Δ12 位具有双键的脂肪酸合成具有反式-11-、顺式-13-共轭双键的脂肪酸的能力；以及 (E) 与 SEQ ID NO: 2 或 13 所示核苷酸序列或其互补序列在严格条件下杂交的核苷酸序列，该核苷酸序列编码一种蛋白质，该蛋白质具有从在Δ12 位具有双键的脂肪酸合成具有反式-11-、顺式-13-共轭双键的脂肪酸的能力。
• US7402418B2
  申请人：——

  公开号：US7402418B2

  公开（公告）日：2008-07-22