Ferrous oxalate is an odorless yellow solid. Insoluble in water and denser in water. Sinks in water. (USCG, 1999)
密度：
2.3 at 68 °F (USCG, 1999)
计算性质
辛醇/水分配系数(LogP)：
-3.52
重原子数：
7
可旋转键数：
0
环数：
0.0
sp3杂化的碳原子比例：
0.0
拓扑面积：
80.3
氢给体数：
0
氢受体数：
4
ADMET
毒理性
副作用
职业性肝毒素 - 第二性肝毒素：在职业环境中的毒性效应潜力是基于人类摄入或动物实验的中毒案例。
Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.
来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations as needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover chemical bums with dry, sterile dressings after decontamination ... . /Oxalate and Related Compounds/
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the unconscious patient. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with lactated Ringer's /SRP: "To keep open", minimal flow rate/. Watch for signs of fluid overload. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Oxalate and Related Compounds/
Maintain an open airway and assist ventilation if necessary. Treat shock caused by hemorrhagic gastrointestinitis aggressively with intravenous crystalloid fluids, and replace blood if needed. Patients are often markedly hypovolemic owing to gastrointestinal losses and third spacing of fluids into the intestinal wall and interstitial space. Treat coma, seizures, and metabolic acidosis if they occur. For seriously intoxicated victims (eg, shock, severe acidosis, and/or serum iron > 500-600 mcg/dL) administer deferoxamine. Monitor the urine for the urine for the characteristic orange or pink deferoxamine-iron complex. Therapy may be stopped when the urine returns to normal or when the serum iron level decreases to the normal range. Prolonged deferoxamine has been associated with adult respiratory distress syndrome and Yersinia sepsis.
Activated charcoal is not effective. Ipecac is not recommended, because it can aggravate iron-induced gastrointestinal irritation and interfere with whole bowel irrigation. Consider gastric lavage if product was a liquid formulation or tablets were chewed. Do-not use phosphate-containing solutions for lavage; these may result in life-threatening hypernatremia, hyperphosphatemia, and hypocalcemia. Bicarbonate and deferoxamine lavage are of doubtful efficacy. Deferoxamine lavage is not effective and may enhance iron absorption. Whole-bowel irrigation is very effective for ingested tablets and may be considered first-line treatment, especially if large numbers of tablets are visible on plain abdominal x-ray. Massive ingestions may lead to concretions or bezoars. Repeated or prolonged whole-bowel irrigation may remove tablets. Endoscopy or surgical gastrotomy is rarely required.
...Bioavailability of Ferosol-1 /(a ferrous oxalate antianemic powder including copper, zinc, and cobalt) was determined/ by giving it to rabbits with experimental posthemorrhagic anemia. ...Iron from Ferosol-1 was found to be well assimilated and to take place in hemopoetic processes of rabbit. /Ferosol-1/
In hemochromatosis and other disorders associated with iron overload, a significant fraction of the total iron in plasma circulates in the form of low molecular weight complexes not bound to transferrin. Efficient and unregulated clearance of this form of iron by the liver may account for the hepatic iron loading and toxicity that characterize these diseases. ...This possibility /was tested/ by examining the hepatic removal process for representative iron complexes in the single-pass perfused rat liver. Hepatic uptake of both ferrous and ferric 55Fe from ultrafiltered human serum was found to be highly efficient and effectively irreversible (single-pass extraction of 1 microM iron, 58-75%). Similar high efficiencies were seen for iron complexed to specific physiologic and nonphysiologic coordinators, including histidine, citrate, fructose, oxalate and glutamate, and tricine. Because of lower plasma flow rates, single-pass extraction of these iron complexes in vivo should be even greater. Autoradiography confirmed that most iron had been removed by parenchymal cells. Hepatic removal from Krebs-tricine buffer was saturable with similar kinetic parameters for ferrous and ferric iron (apparent Km, 14-22 microM; V max, 24-38 nmol/min/g liver). These findings suggest that high levels of non-transferrin-bound iron in plasma may be an important cause of hepatic iron loading in iron overload states.
Thermal decomposition of carbonates, carboxylates, oxalates, acetates, formates, and hydroxides
作者：Jacob Mu、D.D. Perlmutter
DOI：10.1016/0040-6031(81)80175-x
日期：1981.11
Abstract A study is reported of the controlled decomposition of various metal carbonates, carboxylates, oxalates, acetates, formates and hydroxides and their common hydrates, carried out in a thermogravimetric analyzer, a differential scanning calorimeter, and a differential thermal analyzer. Various sample sizes, heating rates, and ambient atmospheres were used to demonstrate their influence on the
Abstract The solidstate redox reaction of iron (III) oxalate with sodium nitrate and tin(II) chloride was investigated in hydrogen atmosphere and helium atmosphere by use of a non-isothermal technique. The evolved gases (EG) formed during the reaction were directly detected by gas chromatography, and the solid products were also identified by XRD, Mossbauer spectra and IR. The results show that the
Metal Complexes of a Hexameric Network Tetrapyrazinoporpyrazine: I. Synthesis and Identification
作者：A. B. Korzhenevskii、L. V. Markova、S. V. Efimova、O. I. Koifman、E. V. Krylova
DOI：10.1007/s11176-005-0356-1
日期：2005.6
Metal complexes of a hexameric network tetrapyrazineporpyrazine were synthesized by template polycyclotetramerization of pyrazine-2,3,5,6-tetracarboxamide in an urea melt in the presence of a corresponding metal acetate; irrespective of the metal, the polymerization degree of the polymeric ligand does not exceed six. A method for structural assessment of such compounds was proposed.
reddish color of the bottom layer of concentrated sulfuric acid, which develops upon the bleeding of the brown layer into the acid. Crystals of the same color form from a solution of ferrous sulfate in concentrated sulfuric acid on saturation with gaseous nitric oxide. The structure of this H3O[Fe(NO)(μ4‐SO4)(μ2‐SO4)0.5}n/n] (1a) is made up from infinite chessboard‐type layers with sulfur on the field
FeZSM-5: A Durable SCR Catalyst for NOxRemoval from Combustion Streams
作者：Xiaobing Feng、W Keith Hall
DOI：10.1006/jcat.1997.1530
日期：1997.3
convenient method of preparing “overexchanged” FeZSM-5catalysts is described that minimizes oxidation of Fe2+to Fe3+during base-exchange and inhibits the formation of Brønsted sites. These catalysts are more active than comparable CuZSM-5 preparations and are much more durable. They are not poisoned by up to 20% H2O and/or 150 ppm of SO2. A 2500-h durability test, carried out at 500°C, is described. It
