(2E)-butenoyl-CoA

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (2E)-butenoyl-CoA
• 英文别名: S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (E)-but-2-enethioate
• 化学式: C₂₅H₄₀N₇O₁₇P₃S
• 分子量: 835.6
• InChiKey: KFWWCMJSYSSPSK-SNAWJCMRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.8
• 重原子数：
  53
• 可旋转键数：
  21
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  389
• 氢给体数：
  9
• 氢受体数：
  22

文献信息

• LovD MUTANTS EXHIBITING IMPROVED PROPERTIES TOWARDS SIMVASTATIN SYNTHESIS
  申请人：Tang Yi

  公开号：US20120190038A1

  公开（公告）日：2012-07-26

  The invention disclosed herein relates to methods and materials for producing simvastatin and related compounds such as huvastatin. In particular, the disclosure teaches that variants of the LovD acyltransferase polypeptide can be engineered to exhibit properties that facilitate their use in the production of simvastatin and/or huvastatin. The materials and processes disclosed herein are designed so that fermentation facilities currently producing lovastatin can be converted to producing simvastatin and related compounds with minimal modifications.
• METHODS AND MATERIALS FOR MAKING SIMVASTATIN AND RELATED COMPOUNDS
  申请人：Tang Yi

  公开号：US20120315680A1

  公开（公告）日：2012-12-13

  The invention disclosed herein relates to methods and materials for producing simvastatin and related compounds such as huvastatin.
• Process For Preparing Hyperpolarized Substrates And Method For MRI
  申请人：Aime Silvio

  公开号：US20130096420A1

  公开（公告）日：2013-04-18

  The present invention generally relates to a process for the preparation of aqueous solutions of hyperpolarized molecules ready for use in in-vivo MR diagnostic imaging, the use thereof as MRI contrast agent in investigation methods for producing diagnostic MR images of a human or non-human animal body organ, region or tissue.
• VARIANT LovD POLYPEPTIDE
  申请人：The Regents of the University of California

  公开号：US20150218531A1

  公开（公告）日：2015-08-06

  The invention disclosed herein relates to methods and materials for producing simvastatin and related compounds such as huvastatin. In particular, the disclosure teaches that variants of the LovD acyltransferase polypeptide can be engineered to exhibit properties that facilitate their use in the production of simvastatin and/or huvastatin. The materials and processes disclosed herein are designed so that fermentation facilities currently producing lovastatin can be converted to producing simvastatin and related compounds with minimal modifications.
• DEHYDRATION CATALYST AND METHOD OF MAKING AND USING THE SAME
  申请人：White Dog Labs, Inc.

  公开号：US20160184810A1

  公开（公告）日：2016-06-30

  A silanized surface, stable selective dehydration catalyst for dienes production, a method for producing a silanized surface, stable, selective dehydration catalyst, and a method for dehydrating at least one of an alkenol and a diol to a diene. The present invention also relates to the fermentation of sugars to afford bio-alkenols that are then separated and converted to a diene using a dehydration catalyst and a method for converting alkenols or diols to dienes with high selectivity and conversion. The dienes are useful in preparing synthetic rubber, plastics copolymers, and fuels.