(10E,12E)-nonadeca-10,12-dienoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (10E,12E)-nonadeca-10,12-dienoic acid
• 化学式: C₁₉H₃₄O₂
• 分子量: 294.5
• InChiKey: HZSYKNUXYNXCPV-XBLVEGMJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  21
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Synergistic conjugated linoleic acid (CLA) and carnitine combination
  申请人：Chopra K. Raj

  公开号：US20060041017A1

  公开（公告）日：2006-02-23

  The present invention relates to the unexpected discovery that a combination of effective amounts of carnitine (in any form, as described in further detail herein) and conjugated linoleic acid (CLA) administered to a patient in need thereof exhibits synergistic activity in treating obesity by reducing fat mass and overall weight as well as one or more of hyperlipidemia, hypercholesterolemia, diabetes (both diabetes mellitus I and II), metabolic syndrome (syndrome X), kidiney failure and high blood pressure, where those conditions exist.

  本发明涉及一项意想不到的发现，即向有需要的患者施用有效量的肉碱（如本文进一步详细描述的任何形式）和共轭亚油酸（CLA）的组合，在治疗肥胖症方面表现出协同活性，可通过减少脂肪量和总体体重以及一种或多种高脂血症、高胆固醇血症、糖尿病（包括 I 型和 II 型糖尿病）、代谢综合征（X 综合征）、肾功能衰竭和高血压（如果存在这些病症）来治疗肥胖症。
• US6440931B1
  申请人：——

  公开号：US6440931B1

  公开（公告）日：2002-08-27
• [EN] SYNERGISTIC CONJUGATED LINOLEIC ACID (CLA) AND CARNITINE COMBINATION<br/>[FR] COMBINAISON SYNERGIQUE D'ACIDE LINOLEIQUE CONJUGUE ET DE CARNITINE
  申请人：TISHCON CORP

  公开号：WO2006023342A2

  公开（公告）日：2006-03-02

  The present invention relates to the unexpected discovery that a combination of effective amounts of camitine (in any form, as described in further detail herein) and conjugated linoleic acid (CLA) administered to a patient in need thereof exhibits synergistic activity in treating obesity by reducing fat mass and overall weight as well as one or more of hyperlipidemia, hypercholesterolemia, diabetes (both diabetes mellitus I and Il), metabolic syndrome (syndrome X), kidiney failure and high blood pressure, where those conditions exist.
• [EN] REACTIVE CARRIER FOR AIR DRYING COATINGS<br/>[FR] charge réactive pour des revêtements séchant à l'air
  申请人：LUBRIZOL ADVANCED MAT INC

  公开号：WO2008048983A2

  公开（公告）日：2008-04-24

  [EN] Reactive carriers are described that can be used with dispersants and pigments in inks and coatings. The reactive carriers have at least two sets of carbon to carbon double bond that are generally reactive in alkyd type drying reactions. The substitution of reactive carriers for solvents in an ink or coating can reduce the volatile organic content of a formulated ink or coating.
  [FR] La présente invention concerne des charges réactives pouvant être utilisées avec des dispersants et des pigments dans des encres et des revêtements. Lesdites charges comportent au moins deux ensembles de liaisons doubles carbone - carbone qui sont généralement réactifs dans des réactions de séchage de type alkydique. La substitution des charges réactives par des solvants dans une encre ou un revêtement peut réduire la teneur en composés organiques volatils d'une encre ou d'un revêtement formulé.