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    —— (7S)-3-(3-fluorophenyl)-7-(3-methoxy-2-prop-2-enoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H20FNO5S
    (7S)-3-(3-fluorophenyl)-7-(3-methoxy-2-prop-2-enoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(3-ethoxy-4-methoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H20FNO5S
    (7S)-7-(3-ethoxy-4-methoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(2-fluorophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C20H13F2NO3S
    (7R)-7-(2-fluorophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-7-(4-methoxycarbonylphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C22H16FNO5S
    (7R)-3-(3-fluorophenyl)-7-(4-methoxycarbonylphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-5-oxo-7-pyridin-3-yl-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C19H13FN2O3S
    (7S)-3-(3-fluorophenyl)-5-oxo-7-pyridin-3-yl-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-5-oxo-7-thiophen-3-yl-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C18H12FNO3S2
    (7R)-3-(3-fluorophenyl)-5-oxo-7-thiophen-3-yl-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-5-oxo-7-(4-prop-2-ynoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H16FNO4S
    (7R)-3-(3-fluorophenyl)-5-oxo-7-(4-prop-2-ynoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(benzenesulfonyl)-7-(2-butoxy-3-methoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C24H25NO5S2
    (7R)-3-(benzenesulfonyl)-7-(2-butoxy-3-methoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-7-(4-bromophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C20H13BrFNO3S
    (7S)-7-(4-bromophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(benzenesulfonyl)-7-(3-methoxy-4-propoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C23H23NO5S2
    (7R)-3-(benzenesulfonyl)-7-(3-methoxy-4-propoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-7-(3,4-difluorophenyl)-3-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H15F2NO4S
    (7R)-7-(3,4-difluorophenyl)-3-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-7-(3-methoxy-4-prop-2-ynoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H18FNO5S
    (7S)-3-(3-fluorophenyl)-7-(3-methoxy-4-prop-2-ynoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(3-ethoxy-4-hydroxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C22H18FNO5S
    (7R)-7-(3-ethoxy-4-hydroxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-7-(4-methoxy-3-prop-2-enoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H20FNO5S
    (7R)-3-(3-fluorophenyl)-7-(4-methoxy-3-prop-2-enoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-7-(2-methylphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H16FNO3S
    (7S)-3-(3-fluorophenyl)-7-(2-methylphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(2-ethoxy-3-methoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H20FNO5S
    (7S)-7-(2-ethoxy-3-methoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(5-chloro-2-fluorophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C20H12ClF2NO3S
    (7S)-7-(5-chloro-2-fluorophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(benzenesulfonyl)-7-(4-hydroxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C19H15NO4S2
    (7R)-3-(benzenesulfonyl)-7-(4-hydroxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-3-(3-fluorophenyl)-7-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H16FNO4S
    (7R)-3-(3-fluorophenyl)-7-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(4-methoxyphenyl)-7-(4-methoxy-3-propoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C25H25NO6S
    (7R)-3-(4-methoxyphenyl)-7-(4-methoxy-3-propoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-7-(3-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H16FNO4S
    (7R)-3-(3-fluorophenyl)-7-(3-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(benzenesulfonyl)-7-(3-hydroxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C19H15NO4S2
    (7R)-3-(benzenesulfonyl)-7-(3-hydroxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-3-(benzenesulfonyl)-7-(2-ethoxy-3-methoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C22H21NO5S2
    (7S)-3-(benzenesulfonyl)-7-(2-ethoxy-3-methoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-3-(benzenesulfonyl)-7-(3-ethoxy-4-hydroxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C21H19NO5S2
    (7R)-3-(benzenesulfonyl)-7-(3-ethoxy-4-hydroxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-3-(benzenesulfonyl)-7-(3-ethoxy-4-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C24H23NO5S2
    (7S)-3-(benzenesulfonyl)-7-(3-ethoxy-4-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-7-(4-cyclopentyloxy-3-methoxyphenyl)-3-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C27H27NO6S
    (7R)-7-(4-cyclopentyloxy-3-methoxyphenyl)-3-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-7-(3-methoxy-2-prop-2-enoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H20FNO5S
    (7R)-3-(3-fluorophenyl)-7-(3-methoxy-2-prop-2-enoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(2,3-dimethoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C22H18FNO5S
    (7R)-7-(2,3-dimethoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(3-bromophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C20H13BrFNO3S
    (7R)-7-(3-bromophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(1,3-benzodioxol-5-yl)-3-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C22H17NO6S
    (7R)-7-(1,3-benzodioxol-5-yl)-3-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-7-(4-methylphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H16FNO3S
    (7R)-3-(3-fluorophenyl)-7-(4-methylphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-7-[3-methoxy-4-(2-methylpropoxy)phenyl]-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C25H24FNO5S
    (7S)-3-(3-fluorophenyl)-7-[3-methoxy-4-(2-methylpropoxy)phenyl]-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-5-oxo-7-(4-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H18FNO4S
    (7R)-3-(3-fluorophenyl)-5-oxo-7-(4-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-7-(3-methoxy-2-propoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H22FNO5S
    (7R)-3-(3-fluorophenyl)-7-(3-methoxy-2-propoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-[3-methoxy-4-(2-methylpropoxy)phenyl]-3-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C26H27NO6S
    (7R)-7-[3-methoxy-4-(2-methylpropoxy)phenyl]-3-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(3-ethoxy-4-propoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C25H24FNO5S
    (7R)-7-(3-ethoxy-4-propoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-5-oxo-7-(2,3,4-trimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H20FNO6S
    (7S)-3-(3-fluorophenyl)-5-oxo-7-(2,3,4-trimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(4-methoxyphenyl)-5-oxo-7-[2-(trifluoromethyl)phenyl]-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C22H16F3NO4S
    (7R)-3-(4-methoxyphenyl)-5-oxo-7-[2-(trifluoromethyl)phenyl]-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(2,5-dimethylphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C22H18FNO3S
    (7S)-7-(2,5-dimethylphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(3,4-diethoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H22FNO5S
    (7R)-7-(3,4-diethoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-7-(3-methoxy-4-propan-2-yloxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H22FNO5S
    (7S)-3-(3-fluorophenyl)-7-(3-methoxy-4-propan-2-yloxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(3-ethoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C22H18FNO4S
    (7R)-7-(3-ethoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(3-bromophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C20H13BrFNO3S
    (7S)-7-(3-bromophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-5-oxo-7-(2,4,5-trimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H20FNO6S
    (7S)-3-(3-fluorophenyl)-5-oxo-7-(2,4,5-trimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(2-chloro-6-fluorophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C20H12ClF2NO3S
    (7S)-7-(2-chloro-6-fluorophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(3-ethoxy-4-prop-2-enoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C25H22FNO5S
    (7R)-7-(3-ethoxy-4-prop-2-enoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(5-chloro-2-fluorophenyl)-3-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H15ClFNO4S
    (7S)-7-(5-chloro-2-fluorophenyl)-3-(4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(4-ethylphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C22H18FNO3S
    (7S)-7-(4-ethylphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-7-(4-methylsulfanylphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H16FNO3S2
    (7R)-3-(3-fluorophenyl)-7-(4-methylsulfanylphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-5-oxo-7-(2,4,5-trimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H20FNO6S
    (7R)-3-(3-fluorophenyl)-5-oxo-7-(2,4,5-trimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid