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    —— (7R)-3-(3-fluorophenyl)-7-(4-methoxy-3-propan-2-yloxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H22FNO5S
    (7R)-3-(3-fluorophenyl)-7-(4-methoxy-3-propan-2-yloxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-5-oxo-7-(2-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H18FNO4S
    (7S)-3-(3-fluorophenyl)-5-oxo-7-(2-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(3-ethoxy-4-prop-2-enoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C25H22FNO5S
    (7S)-7-(3-ethoxy-4-prop-2-enoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(benzenesulfonyl)-7-(4-methoxy-3-prop-2-ynoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C23H19NO5S2
    (7S)-3-(benzenesulfonyl)-7-(4-methoxy-3-prop-2-ynoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-7-(3-butoxy-4-methoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C25H27NO5S2
    (7S)-7-(3-butoxy-4-methoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-7-(4-hydroxy-3,5-dimethoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C22H21NO6S2
    (7R)-7-(4-hydroxy-3,5-dimethoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-7-(4-methoxy-3-propoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C24H25NO5S2
    (7S)-7-(4-methoxy-3-propoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-3-(3-fluorophenyl)-5-oxo-7-(4-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H18FNO4S
    (7S)-3-(3-fluorophenyl)-5-oxo-7-(4-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(3-bromo-4-methoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H15BrFNO4S
    (7S)-7-(3-bromo-4-methoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(benzenesulfonyl)-7-(3-methoxy-4-propoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C23H23NO5S2
    (7S)-3-(benzenesulfonyl)-7-(3-methoxy-4-propoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-3-(benzenesulfonyl)-7-(3,4-dimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C21H19NO5S2
    (7S)-3-(benzenesulfonyl)-7-(3,4-dimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-3-(3-fluorophenyl)-7-(4-methoxy-3-prop-2-ynoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H18FNO5S
    (7R)-3-(3-fluorophenyl)-7-(4-methoxy-3-prop-2-ynoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-7-(3-methoxy-2-propoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H22FNO5S
    (7S)-3-(3-fluorophenyl)-7-(3-methoxy-2-propoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(benzenesulfonyl)-7-[4-(trifluoromethyl)phenyl]-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C20H14F3NO3S2
    (7S)-3-(benzenesulfonyl)-7-[4-(trifluoromethyl)phenyl]-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-7-(4-butoxy-3-methoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C25H27NO5S2
    (7R)-7-(4-butoxy-3-methoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-3-(benzenesulfonyl)-7-[4-(trifluoromethyl)phenyl]-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C20H14F3NO3S2
    (7R)-3-(benzenesulfonyl)-7-[4-(trifluoromethyl)phenyl]-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-3-(3-fluorophenyl)-5-oxo-7-(3-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H18FNO4S
    (7S)-3-(3-fluorophenyl)-5-oxo-7-(3-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-5-oxo-7-thiophen-2-yl-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C18H12FNO3S2
    (7S)-3-(3-fluorophenyl)-5-oxo-7-thiophen-2-yl-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(2,4-dimethoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C22H18FNO5S
    (7S)-7-(2,4-dimethoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(4-chlorophenyl)sulfonyl-7-(2,3,4-trimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C22H20ClNO6S2
    (7S)-3-(4-chlorophenyl)sulfonyl-7-(2,3,4-trimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-7-(4-hydroxyphenyl)-3-(4-methoxyphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C20H17NO5S2
    (7S)-7-(4-hydroxyphenyl)-3-(4-methoxyphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-3-(4-methylphenyl)sulfonyl-7-[4-(trifluoromethyl)phenyl]-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C21H16F3NO3S2
    (7R)-3-(4-methylphenyl)sulfonyl-7-[4-(trifluoromethyl)phenyl]-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-7-(4-hydroxy-3-methoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C21H19NO5S2
    (7R)-7-(4-hydroxy-3-methoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-3-(benzenesulfonyl)-7-(3-cyclopentyloxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C24H23NO4S2
    (7S)-3-(benzenesulfonyl)-7-(3-cyclopentyloxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-7-(3,4-dimethoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C22H21NO5S2
    (7R)-7-(3,4-dimethoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-3-(benzenesulfonyl)-7-(4-hydroxy-3,5-dimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C21H19NO6S2
    (7S)-3-(benzenesulfonyl)-7-(4-hydroxy-3,5-dimethoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-3-(3-fluorophenyl)-5-oxo-7-phenyl-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C20H14FNO3S
    (7R)-3-(3-fluorophenyl)-5-oxo-7-phenyl-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(3-ethoxy-4-prop-2-ynoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C25H20FNO5S
    (7R)-7-(3-ethoxy-4-prop-2-ynoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-(2-ethoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C22H18FNO4S
    (7S)-7-(2-ethoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-7-(4-methoxy-3-prop-2-ynoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C24H18FNO5S
    (7S)-3-(3-fluorophenyl)-7-(4-methoxy-3-prop-2-ynoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-5-oxo-7-(2-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H18FNO4S
    (7R)-3-(3-fluorophenyl)-5-oxo-7-(2-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(3-methoxy-2-propan-2-yloxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C24H25NO5S2
    (7R)-7-(3-methoxy-2-propan-2-yloxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-3-(4-methylphenyl)sulfonyl-7-thiophen-3-yl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C18H15NO3S3
    (7R)-3-(4-methylphenyl)sulfonyl-7-thiophen-3-yl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-7-(4-methoxy-3-prop-2-ynoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C24H21NO5S2
    (7R)-7-(4-methoxy-3-prop-2-ynoxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-7-(4-methoxy-3-propan-2-yloxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C24H25NO5S2
    (7S)-7-(4-methoxy-3-propan-2-yloxyphenyl)-3-(4-methylphenyl)sulfonyl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-3-(benzenesulfonyl)-7-(3-ethoxy-4-propoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C24H25NO5S2
    (7S)-3-(benzenesulfonyl)-7-(3-ethoxy-4-propoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-7-(3-bromo-4-methoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H15BrFNO4S
    (7R)-7-(3-bromo-4-methoxyphenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-5-oxo-7-(4-propan-2-yloxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H20FNO4S
    (7S)-3-(3-fluorophenyl)-5-oxo-7-(4-propan-2-yloxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(benzenesulfonyl)-7-thiophen-2-yl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C17H13NO3S3
    (7R)-3-(benzenesulfonyl)-7-thiophen-2-yl-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-7-(3-chlorophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C20H13ClFNO3S
    (7R)-7-(3-chlorophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(benzenesulfonyl)-7-(4-methylsulfanylphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C20H17NO3S3
    (7S)-3-(benzenesulfonyl)-7-(4-methylsulfanylphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7S)-3-(3-fluorophenyl)-7-(3-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H16FNO4S
    (7S)-3-(3-fluorophenyl)-7-(3-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(benzenesulfonyl)-7-(3-ethoxy-4-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C24H23NO5S2
    (7R)-3-(benzenesulfonyl)-7-(3-ethoxy-4-prop-2-enoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-3-(3-fluorophenyl)-7-(4-hydroxy-3-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H16FNO5S
    (7R)-3-(3-fluorophenyl)-7-(4-hydroxy-3-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-7-[3-(2-amino-2-oxoethoxy)-4-methoxyphenyl]-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C23H19FN2O6S
    (7S)-7-[3-(2-amino-2-oxoethoxy)-4-methoxyphenyl]-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(benzenesulfonyl)-7-(3-ethoxy-4-methoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one —— C22H21NO5S2
    (7R)-3-(benzenesulfonyl)-7-(3-ethoxy-4-methoxyphenyl)-6,7-dihydro-4H-thieno[3,2-b]pyridin-5-one
    —— (7R)-3-(3-fluorophenyl)-7-(3-hydroxy-4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H16FNO5S
    (7R)-3-(3-fluorophenyl)-7-(3-hydroxy-4-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7S)-3-(3-fluorophenyl)-7-(4-hydroxy-3-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H16FNO5S
    (7S)-3-(3-fluorophenyl)-7-(4-hydroxy-3-methoxyphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-7-(4-cyanophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H13FN2O3S
    (7R)-7-(4-cyanophenyl)-3-(3-fluorophenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid
    —— (7R)-3-(3-fluorophenyl)-7-(3-methylphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid —— C21H16FNO3S
    (7R)-3-(3-fluorophenyl)-7-(3-methylphenyl)-5-oxo-6,7-dihydro-4H-thieno[3,2-b]pyridine-2-carboxylic acid