哒嗪类化合物
哒嗪类化合物是指含氮的六元杂环吖嗪类化合物，与嘧啶和吡嗪互为异构体，不溶于石油醚，易溶于甲醇、乙醇和乙醚，并能与水、苯及二甲基甲酰胺混溶。作为一种弱碱，哒嗪能够与苦味酸、盐酸等形成盐类；它不易发生芳香族的亲核或亲电取代反应，对高锰酸钾也非常稳定；通过用钠或醇还原开链，可以转变为1,4-二氨基丁烷。
哒嗪在医药领域广泛应用，作为多种药物的重要原料。例如，长效磺胺SMP、抗疟药4-氨基喹啉和降血压药肼苯哒嗪等均是以哒嗪为原料制备的。此外，哒嗪也用于农药制造，可合成除草剂如“杀草敏”、“乙氨哒酮”、“溴杀草敏”、“哒草醚”、“抑芽丹”、“哒草灭”和“达草止”，以及杀虫剂“打杀磷”。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| 4-甲基-3,6-二羟基哒嗪 | 4-methyl-3,6-pyridazinedione | 5754-18-7 | C5H6N2O2 |
|
| 4-甲基-3(2H)-哒嗪酮 | 4-methylpyridazin-3(2H)-one | 33471-40-8 | C5H6N2O |
|
| 4-溴哒嗪 | 4-bromopyridazine | 115514-66-4 | C4H3BrN2 |
|
| 4-溴吡嗪盐酸盐 | 4-bromopyridazine hydrochloride | 1314777-62-2 | C4H3BrN2*ClH |
|
| 4-溴吡嗪氢溴酸 | 4-bromopyridazine hydrobromide | 1220039-64-4 | BrH*C4H3BrN2 |
|
| 4-溴-6-甲基-3(2H)-哒嗪酮 | 5-bromo-3-methyl-1H-pyridazin-6-one | 954240-46-1 | C5H5BrN2O |
|
| 4-溴-5-(1-吡咯烷基)-3(2H)-哒嗪酮 | 4-bromo-5-(1-pyrrolidinyl)-3(2H)-pyridazinone | 692749-93-2 | C8H10BrN3O |
|
| 4-溴-3,6-哒嗪二酮 | 4-bromo-1,2-dihydropyridazine-3,6-dione | 15456-86-7 | C4H3BrN2O2 |
|
| 4-氰基哒嗪 | pyridazine-4-carbonitrile | 68776-62-5 | C5H3N3 |
|
| 4-氰基-3-氯哒嗪 | 3-chloro-4-pyridazinecarbonitrile | 1445-56-3 | C5H2ClN3 |
|
| 4-氯哒嗪 | 4-Chlor-pyridazin | 17180-92-6 | C4H3ClN2 |
|
| 4-氯-6-苯基-3(2H)-哒嗪酮 | 4-chloro-6-phenylpyridazin-3(2H)-one | 89868-14-4 | C10H7ClN2O |
|
| 4-氯-5-肼-3(2H)-哒嗪 | 4-Chloro-5-hydrazino-3(2H)-pyridazinone | 6959-56-4 | C4H5ClN4O |
|
| 4-氯-5-羟基3(2H)-哒嗪 | 4-chloro-5-hydroxy-3(2H)-pyridazinone | 64178-58-1 | C4H3ClN2O2 |
|
| 4-氯-5-甲氧基哒嗪-3(2H)-酮 | 4-chloro-5-methoxypyridazin-3(2H)-one | 63910-43-0 | C5H5ClN2O2 |
|
| 4-氯-3-哒嗪酮 | 4-chloropyridazin-3(2H)-one | 1677-79-8 | C4H3ClN2O |
|
| 4-氨甲基哒嗪 | pyridazin-4-ylmethanamine | 519020-42-9 | C5H7N3 |
|
| 4-氨基哒嗪 | 4-aminopyridazine | 20744-39-2 | C4H5N3 |
|
| 4-氨基-6-甲基-2H-吡嗪-3-酮 | 3-Hydroxy-4-amino-6-methylpyridazin | 13925-21-8 | C5H7N3O |
|
| 4-氨基-5-氯-3-哒嗪酮 | 4-amino-5-chloro-2<i>H</i>-pyridazin-3-one | 55271-58-4 | C4H4ClN3O |
|
| 4-氨基-3,5-二氯哒嗪 | (3,5-dichloropyridazin-4-yl)amine | 53180-76-0 | C4H3Cl2N3 |
|
| 4-氨基-3(2H)-哒嗪 | 4-amino-3(2H)-pyridazinone | 55271-46-0 | C4H5N3O |
|
| 4-氧代-1-苯基-1,4-二氢-3-哒嗪羧酸 | 4-oxo-1-phenyl-1,4-dihydropyridazine-3-carboxylic acid | 147920-37-4 | C11H8N2O3 |
|
| 4-哒嗪胺盐酸盐(1:1) | pyridazin-4-amine hydrochloride | 1400764-35-3 | C4H5N3*ClH |
|
| 4-哒嗪羧酸 | pyridazine-4-carboxylic acid | 50681-25-9 | C5H4N2O2 |
|
| 4-哒嗪甲醇 | 4-hydroxymethylpyridazine | 50901-43-4 | C5H6N2O |
|
| 4-叔丁基-3,6-二氯哒嗪 | 4-(tert-butyl)-3,6-dichloropyridazine | 22808-29-3 | C8H10Cl2N2 |
|
| 4-乙基哒嗪 | 4-ethylpyridazine | 54248-68-9 | C6H8N2 |
|
| 4-(6-氯哒嗪-3-基)吗啉 | 4-(6-chloropyridazin-3-yl)morpholine | 17259-32-4 | C8H10ClN3O |
|
| 4-(6-氯-3-哒嗪)苯甲醛 | 4-(6-chloropyridazin-3-yl)benzaldehyde | 914349-19-2 | C11H7ClN2O |
|
| 4,7-二氯-1H-咪唑并[4,5-d]吡嗪 | 4,7-dichloro-1H-imidazo[4,5-d]pyridazine | 17998-43-5 | C5H2Cl2N4 |
|
| 4,6-二羟基哒嗪-3-羧酸 | 4,6-dihydroxypyridazine-3-carboxylic acid | 1442437-21-9 | C5H4N2O4 |
|
| 4,6-二羟基吡嗪-3-羧酸乙酯 | ethyl 4,6-dihydroxypyridazine-3-carboxylate | 1352925-63-3 | C7H8N2O4 |
|
| 4,6-二氯哒嗪-3-羧酸甲酯 | methyl 4,6-dichloropyridazine-3-carboxylate | 372118-01-9 | C6H4Cl2N2O2 |
|
| 4,6-二氯-3-苯基哒嗪 | 3-Phenyl-4,6-dichloropyridazine | 40020-05-1 | C10H6Cl2N2 |
|
| 4,6-二氯-3-哒嗪甲酸 | 4,6-dichloropyridazine-3-carboxylic acid | 1040246-87-4 | C5H2Cl2N2O2 |
|
| 4,5-哒嗪二羧酸 | pyridazine-4,5-dicarboxylic acid | 59648-14-5 | C6H4N2O4 |
|
| 4,5-二甲基哒嗪 | 4,5-dimethylpyridazine | 38283-35-1 | C6H8N2 |
|
| 4,5-二甲基-3,6-二羟基哒嗪 | 4,5-dimethylpyridazine-3,6-diol | 5754-17-6 | C6H8N2O2 |
|
| 4,5-二溴哒嗪-3-酮 | 4,5-dibromo-3(2H)pyridazinone | 5788-58-9 | C4H2Br2N2O |
|
| 4,5-二溴-2-苯基-2,3-二氢哒嗪-3-酮 | 4,5-dibromo-2-phenylpyridazin-3(2H)-one | 14305-08-9 | C10H6Br2N2O |
|
| 4,5-二氯哒嗪-3,6-二醇 | 4,5-dichloromaleic hydrazide | 6641-32-3 | C4H2Cl2N2O2 |
|
| 4,5-二氯-3-羟基哒嗪 | 4,5-dichloro-2H-pyridazin-3-one | 932-22-9 | C4H2Cl2N2O |
|
| 4,5-二氯-2-苄基-3(2H)-哒嗪 | 2-benzyl-4,5-dichloro-3(2H)-pyridazinone | 41933-33-9 | C11H8Cl2N2O |
|
| 4,5-二氯-2-甲基哒嗪-3-酮 | 4,5-dichloro-2-methyl-3(2H)-pyridazinone | 933-76-6 | C5H4Cl2N2O |
|
| 4,5-二氯-2-(3-甲苯基)哒嗪-3-酮 | LCS-1 | 41931-13-9 | C11H8Cl2N2O |
|
| 4,5-二氯-2-(2-吡啶基)哒嗪-3-酮 | 4,5-dichloro-2-pyridine-2-ylpyridazin-3(2H)-one | 78389-19-2 | C9H5Cl2N3O |
|
| 4,5-二氨基吡嗪 | pyridazine-4,5-diamine | 28682-70-4 | C4H6N4 |
|
| 4,5-二氢-6-苯基-3(2H)-哒嗪酮 | 6-phenyl-2,3,4,5-tetrahydropyridazin-3-one | 1011-46-7 | C10H10N2O |
|
| 4,5-二氢-6-甲基哒嗪-3(2H)-酮 | 4,5-Dihydro-6-methylpyridazin-3(2H)-one | 5157-08-4 | C5H8N2O |
|
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