哒嗪类化合物
哒嗪类化合物是指含氮的六元杂环吖嗪类化合物，与嘧啶和吡嗪互为异构体，不溶于石油醚，易溶于甲醇、乙醇和乙醚，并能与水、苯及二甲基甲酰胺混溶。作为一种弱碱，哒嗪能够与苦味酸、盐酸等形成盐类；它不易发生芳香族的亲核或亲电取代反应，对高锰酸钾也非常稳定；通过用钠或醇还原开链，可以转变为1,4-二氨基丁烷。
哒嗪在医药领域广泛应用，作为多种药物的重要原料。例如，长效磺胺SMP、抗疟药4-氨基喹啉和降血压药肼苯哒嗪等均是以哒嗪为原料制备的。此外，哒嗪也用于农药制造，可合成除草剂如“杀草敏”、“乙氨哒酮”、“溴杀草敏”、“哒草醚”、“抑芽丹”、“哒草灭”和“达草止”，以及杀虫剂“打杀磷”。
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| 3-氯-6-乙基氨基哒嗪 | 3-Chloro-6-ethylaminopyridazine | 68588-39-6 | C6H8ClN3 |
| 3-氯-6-丙基氧基哒嗪 | 3-chloro-6-(propyloxy)pyridazine | 5788-60-3 | C7H9ClN2O |
| 3-氯-6-三氟甲基哒嗪 | 3-chloro-6-(trifluormethyl)pyridazine | 258506-68-2 | C5H2ClF3N2 |
| 3-氯-6-[3-(氯甲基)-1-哌啶基]哒嗪 | 3-Chloro-6-(3-(chloromethyl)piperidin-1-yl)pyridazine | 1185310-44-4 | C10H13Cl2N3 |
| 3-氯-6-(甲氧基甲基)哒嗪 | 3-Chloro-6-(methoxymethyl)pyridazine | 1289385-57-4 | C6H7ClN2O |
| 3-氯-6-(甲基磺酰基)吡嗪 | 3-chloro-6-(methylsulfonyl)pyridazine | 7145-62-2 | C5H5ClN2O2S |
| 3-氯-6-(异丙基氨基)哒嗪 | 3-Chlor-6-isopropylamino-pyridazin | 1007-55-2 | C7H10ClN3 |
| 3-氯-6-(乙氧基甲基)哒嗪 | 3-Chloro-6-(ethoxymethyl)pyridazine | 1289386-87-3 | C7H9ClN2O |
| 3-氯-6-(4-硝基苯氧基)哒嗪 | 3-chloro-6-(4-nitrophenoxy)pyridazine | 1490-54-6 | C10H6ClN3O3 |
| 3-氯-6-(4-甲基哌嗪)-1-哒嗪 | 3-chloro-6-(4-methylpiperazin-1-yl)pyridazine | 27464-17-1 | C9H13ClN4 |
| 3-氯-6-(4-氯苯基)-哒嗪 | 3-(4-chlorophenyl)-6-chloropyridazine | 58059-29-3 | C10H6Cl2N2 |
| 3-氯-6-(4-氯-1-哌啶基)哒嗪 | 3-Chloro-6-(4-chloropiperidin-1-yl)pyridazine | 1185318-06-2 | C9H11Cl2N3 |
| 3-氯-6-(4-氟苯基)吡嗪 | 3-chloro-6-(4-fluorophenyl)pyridazine | 66548-52-5 | C10H6ClFN2 |
| 3-氯-6-(3-甲氧基丙基氨基)哒嗪 | 6-chloro-N-(3-methoxypropyl)pyridazin-3-amine | 898656-60-5 | C8H12ClN3O |
| 3-氯-6-(3-氯-1-哌啶基)哒嗪 | 3-Chloro-6-(3-chloropiperidin-1-yl)pyridazine | 1185310-37-5 | C9H11Cl2N3 |
| 3-氯-6-(3-哌啶基甲氧基)哒嗪盐酸盐 | 3-Chloro-6-(piperidin-3-ylmethoxy)-pyridazine hydrochloride | 1185311-75-4 | C10H15Cl2N3O |
| 3-氯-6-(1H-咪唑并L-1-基)哒嗪 | 3-chloro-6-(1H-imidazol-1-yl)pyridazine | 71037-71-3 | C7H5ClN4 |
| 3-氯-6-(1H-吡唑-1-基)哒嗪 | 3-chloro-6-(1H-pyrazol-1-yl)pyridazine | 29334-66-5 | C7H5ClN4 |
| 3-氯-6-(1H-吡咯-1-基)哒嗪 | 3-chloro-6-pyrrol-1-ylpyridazine | 5096-76-4 | C8H6ClN3 |
| 3-氯-6-(1-甲基-1H-4-吡唑基)哒嗪 | 3-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyridazine | 943541-20-6 | C8H7ClN4 |
| 3-氯-5-甲酸哒嗪 | 6-chloropyridazine-4-carboxylic acid | 1256794-24-7 | C5H3ClN2O2 |
| 3-氯-5-甲氧基哒嗪 | 3-chloro-5-methoxy-pyridazine | 123696-02-6 | C5H5ClN2O |
| 3-氯-5-甲基哒嗪 | 3-chloro-5-methylpyridazine | 89283-31-8 | C5H5ClN2 |
| 3-氯-4-甲基哒嗪 | 3-chloro-4-methylpyridazine | 68206-04-2 | C5H5ClN2 |
| 3-氯-4-甲基-6-苯基哒嗪 | 3-chloro-4-methyl-6-phenylpyridazine | 28657-39-8 | C11H9ClN2 |
| 3-氯-4-氨基哒嗪 | 5-Amino-6-chlor-pyridazin | 55928-83-1 | C4H4ClN3 |
| 3-氯-4-哒嗪甲酸乙酯 | ethyl 3-chloro-4-pyridazinecarboxylate | 1445-54-1 | C7H7ClN2O2 |
| 3-氨基哒嗪盐酸盐 | 3-aminopyridazine hydrochloride | 89203-22-5 | C4H5N3*ClH |
| 3-氨基哒嗪-4-甲酸甲酯 | methyl 3-aminopyridazine-4-carboxylate | 1256633-18-7 | C6H7N3O2 |
| 3-氨基哒嗪-4-甲酸乙酯 | ethyl 3-aminopyridazine-4-carboxylate | 716325-02-9 | C7H9N3O2 |
| 3-氨基-6-甲氧基哒嗪 | 6-methoxy-3-pyridazinamine | 7252-84-8 | C5H7N3O |
| 3-氨基-6-环丙基哒嗪 | 6-cyclopropylpyridazin-3-amine | 1159814-07-9 | C7H9N3 |
| 3-氨基-6-氯哒嗪 | 3-Amino-6-chloropyridazine | 5469-69-2 | C4H4ClN3 |
| 3-氨基-6-氯咪唑并[1,2-B]哒嗪 | 3-amino-6-chloroimidazo[1,2-b]pyridazine | 166176-45-0 | C6H5ClN4 |
| 3-氨基-6-氯-4-甲基吡嗪 | 3-amino-6-chloro-4-methylpyridazine | 64068-00-4 | C5H6ClN3 |
| 3-氨基-6-(苯硫基)哒嗪 | 3-amino-6-phenylthiopyridazine | 90844-35-2 | C10H9N3S |
| 3-氨基-6-(吗啉-4-基)吡嗪 | 6-morpholinopyridazin-3-amine | 66346-91-6 | C8H12N4O |
| 3-氨基-6-(乙硫基)哒嗪 | 3-amino-6-ethylthiopyridazine | 89465-42-9 | C6H9N3S |
| 3-氨基-6-(丙硫基)哒嗪 | 6-propylthiopyridazin-3-amine | 113121-36-1 | C7H11N3S |
| 3-氨基-6-(4-甲氧基苯基)哒嗪 | 6-(4-methoxyphenyl)pyridazin-3-amine | 4776-87-8 | C11H11N3O |
| 3-氨基-6-(4-氯苯基)哒嗪 | 6-(4-chlorophenyl)pyridazin-3-amine | 58059-47-5 | C10H8ClN3 |
| 3-氨基-5-甲基哒嗪 | 5-methylpyridazin-3-amine | 144294-43-9 | C5H7N3 |
| 3-氨基-5-甲基-6-氯哒嗪 | 6-chloro-5-methylpyridazin-3-amine | 66346-87-0 | C5H6ClN3 |
| 3-氨基-4-甲基哒嗪 | 4-methylpyridazin-3-amine | 90568-15-3 | C5H7N3 |
| 3-氨基-4-溴-6-氯哒嗪 | 4-bromo-6-chloro-3-pyridazineamine | 446273-59-2 | C4H3BrClN3 |
| 3-氨基-4-哒嗪甲腈 | 3-aminopyridazine-4-carbonitrile | 119581-52-1 | C5H4N4 |
| 3-氨基-4,6-二氯哒嗪 | 3-amino-4,6-dichloropyridazine | 1161847-28-4 | C4H3Cl2N3 |
| 3-氨基--6-氰基哒嗪 | 6-aminopyridazine-3-carbonitrile | 340759-46-8 | C5H4N4 |
| 3-氧代-6-氯-2,3-二氢哒嗪-4-甲酸甲酯 | 6-Chlor-4-ethoxycarbonyl-3(2H)-pyridazinon | 61404-41-9 | C7H7ClN2O3 |
| 3-氧代-2,3-二氢哒嗪-4-甲酰胺 | 3-Oxo-2,3-dihydropyridazine-4-carboxamide | 2125-92-0 | C5H5N3O2 |
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