哒嗪类化合物
哒嗪类化合物是指含氮的六元杂环吖嗪类化合物，与嘧啶和吡嗪互为异构体，不溶于石油醚，易溶于甲醇、乙醇和乙醚，并能与水、苯及二甲基甲酰胺混溶。作为一种弱碱，哒嗪能够与苦味酸、盐酸等形成盐类；它不易发生芳香族的亲核或亲电取代反应，对高锰酸钾也非常稳定；通过用钠或醇还原开链，可以转变为1,4-二氨基丁烷。
哒嗪在医药领域广泛应用，作为多种药物的重要原料。例如，长效磺胺SMP、抗疟药4-氨基喹啉和降血压药肼苯哒嗪等均是以哒嗪为原料制备的。此外，哒嗪也用于农药制造，可合成除草剂如“杀草敏”、“乙氨哒酮”、“溴杀草敏”、“哒草醚”、“抑芽丹”、“哒草灭”和“达草止”，以及杀虫剂“打杀磷”。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| 3-乙酰氨基-4-甲基哒嗪 | N-(4-methylpyridazin-3-yl)acetamide | 1314406-37-5 | C7H9N3O |
|
| 3-乙酰基-6-氯咪唑并[1,2-b]哒嗪 | 1-(6-chloroimidazo[1,2-b]pyridazin-3-yl)ethanone | 90734-71-7 | C8H6ClN3O |
|
| 3-乙酰哒嗪 | 3-acetylpyridazine | 1122-63-0 | C6H6N2O |
|
| 3-乙炔咪唑并[1,2-b]吡嗪 | 3-ethynylimidazo[1,2-b]pyridazine | 943320-61-4 | C8H5N3 |
|
| 3-乙基哒嗪 | 3-ethyl-pyridazine | 28200-51-3 | C6H8N2 |
|
| 3-丙氧基哒嗪 | 3-(propyloxy)pyridazine | 748141-89-1 | C7H10N2O |
|
| 3-[(6-氨基-3-哒嗪基)甲基]苯腈 | 3-(6-Amino-pyridazin-3-ylmethyl)-benzonitrile | 874338-92-8 | C12H10N4 |
|
| 3-[(6-氨基-3-哒嗪基)甲基]苯甲酸甲酯 | 3-[(6-amino-3-pyridazinyl)methyl]-benzoic acid methyl ester | 874338-90-6 | C13H13N3O2 |
|
| 3-[(2-溴-3-吡啶基)氧基]-6-氯哒嗪 | 3-(2-Bromo-pyridin-3-yloxy)-6-chloro-pyridazine | 1065484-70-9 | C9H5BrClN3O |
|
| 3-(肼基)哒嗪盐酸盐 | 3-hydrazinopyridazine hydrochloride | 117043-87-5 | C4H6N4*ClH |
|
| 3-(甲基氨基)哒嗪-4-甲腈 | 3-(methylamino)pyridazine-4-carbonitrile | 1256268-95-7 | C6H6N4 |
|
| 3-(溴甲基)哒嗪 | 3-(bromomethyl)pyridazine | 60023-36-1 | C5H5BrN2 |
|
| 3-(溴甲基)-6-氯吡嗪 | 3-(bromomethyl)-6-chloropyridazine | 859161-48-1 | C5H4BrClN2 |
|
| 3-(氯甲基)哒嗪盐酸盐 | 3-(chloromethyl)pyridazine hydrochloride | 27349-66-2 | C5H5ClN2*ClH |
|
| 3-(氯甲基)哒嗪 | 3-(chloromethyl)pyridazine | 41227-72-9 | C5H5ClN2 |
|
| 3-(6-羰基-1,6-二氢-3-哒嗪基)苯氰 | 3-(6-oxo-1,6-dihydropyridazin-3-yl)benzonitrile | 52240-08-1 | C11H7N3O |
|
| 3-(4-溴苯基)-6-氯哒嗪 | 3-(p-bromophenyl)-6-chloropyridazine | 66548-50-3 | C10H6BrClN2 |
|
| 3,8-二溴-6-氯咪唑并[1,2-b]吡嗪 | 3,8-dibromo-6-chloroimidazo[1,2-b]pyridazine | 933035-31-5 | C6H2Br2ClN3 |
|
| 3,6-哒嗪二甲酸 | pyridazine-3,6-dicarboxylic acid | 57266-70-3 | C6H4N2O4 |
|
| 3,6-二碘哒嗪 | 3,6-diiodopyridazine | 20698-04-8 | C4H2I2N2 |
|
| 3,6-二甲氧基哒嗪-4-羧酸 | 3,6-dimethoxypyridazine-4-carboxylic acid | 89694-24-6 | C7H8N2O4 |
|
| 3,6-二甲氧基吡嗪 | 3,6-dimethoxypyridazine | 4603-59-2 | C6H8N2O2 |
|
| 3,6-二甲基哒嗪 | 3,6-dimethylpyridazine | 1632-74-2 | C6H8N2 |
|
| 3,6-二溴哒嗪 | 3,6-dibromopyridazine | 17973-86-3 | C4H2Br2N2 |
|
| 3,6-二溴-4-甲基吡嗪 | 3,6-dibromo-4-methylpyridazine | 89284-10-6 | C5H4Br2N2 |
|
| 3,6-二氯哒嗪-4-醇 | 3,6-dichloropyridazin-4-ol | 2779-81-9 | C4H2Cl2N2O |
|
| 3,6-二氯哒嗪-4-胺 | 3,6-dichloropyridazin-4-amine | 823-58-5 | C4H3Cl2N3 |
|
| 3,6-二氯哒嗪-4-羧酸甲酯 | methyl 3,6-dichloropyridazine-4-carboxylate | 286946-24-5 | C6H4Cl2N2O2 |
|
| 3,6-二氯哒嗪-4-羧酸 | 3,6-dichloropyridazin-4-carboxylic acid | 51149-08-7 | C5H2Cl2N2O2 |
|
| 3,6-二氯哒嗪 | 3,6-dichlorpyridazine | 141-30-0 | C4H2Cl2N2 |
|
| 3,6-二氯吡嗪-4-羧酸乙酯 | ethyl 3,6-dichloropyridazine-4-carboxylate | 34127-22-5 | C7H6Cl2N2O2 |
|
| 3,6-二氯-4-碘哒嗪 | 3,6-Dichloro-4-iodopyridazine | 130825-13-7 | C4HCl2IN2 |
|
| 3,6-二氯-4-甲氧基吡嗪 | 3,6-dichloro-4-methoxypyridazine | 70952-62-4 | C5H4Cl2N2O |
|
| 3,6-二氯-4-甲基哒嗪 | 3,6-dichloro-4-methylpyridazine | 19064-64-3 | C5H4Cl2N2 |
|
| 3,6-二氯-4-异丙基哒嗪 | 3,6-dichloro-4-isopropylpyridazine | 107228-51-3 | C7H8Cl2N2 |
|
| 3,6-二氯-4-吡嗪羧醛 | 4-Formyl-3,6-dichloropyridazine | 130825-10-4 | C5H2Cl2N2O |
|
| 3,6-二氯-4-乙基吡嗪 | 3,6-dichloro-4-ethylpyridazine | 107228-54-6 | C6H6Cl2N2 |
|
| 3,6-二氯-4-(4-吡啶基)哒嗪 | 3,6-dichloro-4-(pyridin-4-yl)pyridazine | 202931-70-2 | C9H5Cl2N3 |
|
| 3,6-二氯-4,5-二甲基哒嗪 | 3,6-dichloro-4,5-dimethylpyridazine | 34584-69-5 | C6H6Cl2N2 |
|
| 3,6-二氯-4,5-二乙基吡嗪 | 3,6-dichloro-4,5-diethylpyridazine | 107228-53-5 | C8H10Cl2N2 |
|
| 3,6-二氨基哒嗪 | pyridazine-3,6-diamine | 61070-99-3 | C4H6N4 |
|
| 3,6-二氟哒嗪 | 3,6-difluoropyridazine | 33097-39-1 | C4H2F2N2 |
|
| 3,6-二(吡啶-4-基)哒嗪 | 3,6-bis(4-pyridyl)-1,2-diazine | 204254-06-8 | C14H10N4 |
|
| 3,6-二(1H-咪唑并L-1-基)哒嗪 | 3,6-bis(imidazol-1-yl)pyridazine | 177648-99-6 | C10H8N6 |
|
| 3,5-二溴哒嗪 | 3,5-dibromopyridazine | 1196155-35-7 | C4H2Br2N2 |
|
| 3,5-二氯哒嗪 | 3,5-dichloropyridazine | 1837-55-4 | C4H2Cl2N2 |
|
| 3,4-二氯哒嗪 | 3,4-dichloropyridazine | 1677-80-1 | C4H2Cl2N2 |
|
| 3,4-二氯-6-苯基哒嗪 | 3,4-dichloro-6-phenylpyridazine | 64942-62-7 | C10H6Cl2N2 |
|
| 3,4-二氯-5-氨基哒嗪 | 5-amino-3,4-dichloropyridazine | 89180-50-7 | C4H3Cl2N3 |
|
| 3,4,6-三溴哒嗪 | 3,4,6-tribromopyridazine | 55928-86-4 | C4HBr3N2 |
|
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