哒嗪类化合物
哒嗪类化合物是指含氮的六元杂环吖嗪类化合物，与嘧啶和吡嗪互为异构体，不溶于石油醚，易溶于甲醇、乙醇和乙醚，并能与水、苯及二甲基甲酰胺混溶。作为一种弱碱，哒嗪能够与苦味酸、盐酸等形成盐类；它不易发生芳香族的亲核或亲电取代反应，对高锰酸钾也非常稳定；通过用钠或醇还原开链，可以转变为1,4-二氨基丁烷。
哒嗪在医药领域广泛应用，作为多种药物的重要原料。例如，长效磺胺SMP、抗疟药4-氨基喹啉和降血压药肼苯哒嗪等均是以哒嗪为原料制备的。此外，哒嗪也用于农药制造，可合成除草剂如“杀草敏”、“乙氨哒酮”、“溴杀草敏”、“哒草醚”、“抑芽丹”、“哒草灭”和“达草止”，以及杀虫剂“打杀磷”。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| 3-苯基哒嗪 | 3-phenylpyridazine | 15150-84-2 | C10H8N2 |
|
| 3-肼基哒嗪盐酸盐 | 3-hydrazinylpyridazine | 40972-16-5 | C4H6N4 |
|
| 3-肼基-6-苯基吡嗪 | 3-hydrazino-6-phenylpyridazine | 38956-80-8 | C10H10N4 |
|
| 3-肼基-6-甲基哒嗪 | 3-hydrazinyl-6-methylpyridazine | 38956-79-5 | C5H8N4 |
|
| 3-羧基哒嗪 | pyridazine-3-carboxylic acid | 2164-61-6 | C5H4N2O2 |
|
| 3-羟基哒嗪-4-羧酸乙酯 | ethyl 2,3-dihydro-3-oxopyridazine-4-carboxylate | 1445-55-2 | C7H8N2O3 |
|
| 3-羟基-6-氯哒嗪 | 6-chloro-2H-pyridazin-3-one | 19064-67-6 | C4H3ClN2O |
|
| 3-羟基-4,5-二氯-6-硝基吡嗪 | 4,5-dichloro-6-nitropyridazin-3(2H)-one | 13645-43-7 | C4HCl2N3O3 |
|
| 3-碘哒嗪 | 3-iodopyridazine | 65202-53-1 | C4H3IN2 |
|
| 3-碘-6-甲基哒嗪 | 3-iodo-6-methylpyridazine | 1618-47-9 | C5H5IN2 |
|
| 3-硝基-6-氯咪唑并[1,2-b]哒嗪 | 6-chloro-3-nitroimidazo[1,2-b]pyridazine | 18087-76-8 | C6H3ClN4O2 |
|
| 3-甲氨基哒嗪盐酸盐 | pyridazin-3-ylmethanamine hydrochloride | 1228788-25-7 | C5H7N3*ClH |
|
| 3-甲氧基-6-甲基哒嗪 | 3-methoxy-6-methylpyridazine | 17644-83-6 | C6H8N2O |
|
| 3-甲基哒嗪 | 3-methylpyridazine | 1632-76-4 | C5H6N2 |
|
| 3-甲基-6-(1-甲基肼基)哒嗪 | 3-methyl-6-(1-methylhydrazino)pyridazine | 175135-44-1 | C6H10N4 |
|
| 3-甲基-5-苯基哒嗪 | 3-methyl-5-phenylpyridazine | 184021-10-1 | C11H10N2 |
|
| 3-溴哒嗪 | 3-bromopyridazine | 88491-61-6 | C4H3BrN2 |
|
| 3-溴咪唑并[1,2-B]哒嗪 | 3-bromoimidazo[1,2-b]pyridazine | 18087-73-5 | C6H4BrN3 |
|
| 3-溴-N-丙基咪唑并[1,2-B]哒嗪-6-胺 | 3-bromo-N-propylimidazo[1,2-b]pyridazin-6-amine | 1034621-79-8 | C9H11BrN4 |
|
| 3-溴-6-甲基哒嗪 | 6-methyl-3-bromopyridazine | 65202-58-6 | C5H5BrN2 |
|
| 3-溴-6-氯哒嗪 | 3-bromo-6-chloropyridazine | 89089-18-9 | C4H2BrClN2 |
|
| 3-溴-6-氯咪唑并[1,2-b]哒嗪 | 3-bromo-6-chloro-imidazo[1,2-b]pyridazine | 13526-66-4 | C6H3BrClN3 |
|
| 3-溴-6-氯-2-苯基咪唑[1,2-B]并哒嗪 | 3-Brom-6-chlor-2-phenylimidazo<1,2-b>pyridazin | 19601-74-2 | C12H7BrClN3 |
|
| 3-氰基哒嗪 | pyridazine-3-carbonitrile | 53896-49-4 | C5H3N3 |
|
| 3-氰基-6-氯哒嗪 | 6-chloropyridazine-3-carbonitrile | 35857-89-7 | C5H2ClN3 |
|
| 3-氯哒嗪 | 3-chloropyridazine | 1120-95-2 | C4H3ClN2 |
|
| 3-氯-吡嗪-4-羧酸 | 3-chloro-pyridazine-4-carboxylic acid | 1023307-42-7 | C5H3ClN2O2 |
|
| 3-氯-7H-吡咯并[2,3-C] 哒嗪 | 3-chloro-7H-pyrrolo[2,3-c]pyridazine | 1207625-18-0 | C6H4ClN3 |
|
| 3-氯-6-邻-甲苯哒嗪 | 3-(4-methylphenyl)-6-chloropyridazine | 2165-06-2 | C11H9ClN2 |
|
| 3-氯-6-苯基哒嗪-4-醇 | 3-chloro-6-phenylpyridazin-4-ol | 89868-13-3 | C10H7ClN2O |
|
| 3-氯-6-苯基哒嗪 | 3-chloro-6-phenylpyradazine | 20375-65-9 | C10H7ClN2 |
|
| 3-氯-6-肼基哒嗪 | 3-Chloro-6-hydrazinopyridazine | 17284-97-8 | C4H5ClN4 |
|
| 3-氯-6-碘哒嗪 | 3-chloro-6-iodopyridazine | 135034-10-5 | C4H2ClIN2 |
|
| 3-氯-6-甲氧基哒嗪 | 3-chloro-6-methoxypyridazine | 1722-10-7 | C5H5ClN2O |
|
| 3-氯-6-甲基氨基哒嗪 | 3-Chlor-6-methylamino-pyridazin | 14959-32-1 | C5H6ClN3 |
|
| 3-氯-6-甲基哒嗪 | 3-chloro-6-methylpyridazine | 1121-79-5 | C5H5ClN2 |
|
| 3-氯-6-环丙基氨基哒嗪 | 6-chloro-N-cyclopropylpyridazin-3-amine | 941294-45-7 | C7H8ClN3 |
|
| 3-氯-6-氯甲基哒嗪 | 3-chloro-6-(chloromethyl)pyridazine | 120276-59-7 | C5H4Cl2N2 |
|
| 3-氯-6-戊基氨基哒嗪 | 6-Chloro-N-pentylpyridazin-3-amine | 941294-42-4 | C9H14ClN3 |
|
| 3-氯-6-异丙基哒嗪 | 3-chloro-6-isopropylpyridazine | 570416-35-2 | C7H9ClN2 |
|
| 3-氯-6-巯基哒嗪 | 6-chloropyridazine-3-thiol | 3916-78-7 | C4H3ClN2S |
|
| 3-氯-6-吡咯烷-1-基-哒嗪 | 3-chloro-6-(pyrrolidin-1-yl)pyridazine | 66346-85-8 | C8H10ClN3 |
|
| 3-氯-6-乙酯哒嗪 | 3-chloro-6-(ethyloxy)pyridazine | 17321-20-9 | C6H7ClN2O |
|
| 3-氯-6-乙基氨基哒嗪 | 3-Chloro-6-ethylaminopyridazine | 68588-39-6 | C6H8ClN3 |
|
| 3-氯-6-丙基氧基哒嗪 | 3-chloro-6-(propyloxy)pyridazine | 5788-60-3 | C7H9ClN2O |
|
| 3-氯-6-三氟甲基哒嗪 | 3-chloro-6-(trifluormethyl)pyridazine | 258506-68-2 | C5H2ClF3N2 |
|
| 3-氯-6-[3-(氯甲基)-1-哌啶基]哒嗪 | 3-Chloro-6-(3-(chloromethyl)piperidin-1-yl)pyridazine | 1185310-44-4 | C10H13Cl2N3 |
|
| 3-氯-6-(甲氧基甲基)哒嗪 | 3-Chloro-6-(methoxymethyl)pyridazine | 1289385-57-4 | C6H7ClN2O |
|
| 3-氯-6-(甲基磺酰基)吡嗪 | 3-chloro-6-(methylsulfonyl)pyridazine | 7145-62-2 | C5H5ClN2O2S |
|
| 3-氯-6-(异丙基氨基)哒嗪 | 3-Chlor-6-isopropylamino-pyridazin | 1007-55-2 | C7H10ClN3 |
|
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