2-ethyl-2-methyl-tetrahydro-pyran-4-one semicarbazone | 90951-44-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 2-ethyl-2-methyl-tetrahydro-pyran-4-one semicarbazone
• 英文别名: 2-Aethyl-2-methyl-tetrahydro-pyran-4-on-semicarbazon
• CAS: 90951-44-3
• 化学式: C₉H₁₇N₃O₂
• 分子量: 199.253
• InChiKey: PFPFUKLWHUBHIU-YRNVUSSQSA-N

物化性质

• 熔点：
  163-164 °C
• 密度：
  1.22±0.1 g/cm3(Predicted)

反应信息

• 作为产物：
  描述：

  S-(4-叔-丁基苯甲基)[2-(1-甲基丁基)吡啶-3-基]硫代氨基甲酸酯 、 alkaline earth salt of/the/ methylsulfuric acid 生成 2-ethyl-2-methyl-tetrahydro-pyran-4-one semicarbazone
  参考文献：
  名称：

  Conjugate intra- and intermolecular addition mediated by methoxide anion on polymeric support

  摘要：

  By treatment with methoxide anion on polymeric support (IRA 900), chiral beta -oxo or beta -sulphonylamides 2 bearing an alpha,beta -unsaturated ester gave 3,4-disubstituted pyrrolidin-2-ones 3 as easily separable diastereomeric mixtures in good yield and moderate-to-good stereoselection. The polymeric reagent was also effective in promoting both intermolecular conjugate addition and alkylation reactions. (C) 2000 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(00)01490-8

文献信息

• The Role of the Medical School in Rural Graduate Medical Education: Pipeline or Control Valve?
  作者：Howard K. Rabinowitz、Nina P. Paynter

  DOI：10.1111/j.1748-0361.2000.tb00468.x

  日期：2000.6

  Abstract: Although rural‐based graduate medical education is critically important in the training of competent rural family physicians, the number of physicians selecting these programs is highly dependent on what happens earlier in the pipeline, i.e, during medical school. Using the experience and outcomes research from Jefferson Medical Colleges Physician Shortage Area Program, as well as from published literature describing six other medical school programs with similar goals, this paper addresses the important role of these programs in substantially increasing the number of physicians interested in rural family practice. Although each of these programs differs in its structure, all contain three core features: a strong institutional mission; the targeted selection of students likely to practice in rural areas, predominantly those with rural backgrounds; and a focus on primary care, especially family practice. Outcomes show that all seven programs have been highly successful. Medical schools, therefore, can have a major impact on the number of rural physicians they produce by acting not only as a pipeline or conduit to residency programs, but also as a control valve, beginning as early as the admissions process. In order to maximize their impact on the supply and training of rural family physicians, rural residency programs should understand, support, collaborate with and help develop medical school programs whose mission is to provide rural physicians.
• The Residency Review Committee and Rural Programs
  作者：Mary Alice Parsons、Diane Beebe

  DOI：10.1111/j.1748-0361.2000.tb00466.x

  日期：2000.6