| 144547-81-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 144547-81-9
• 化学式: C₂₆H₂₈Cl₂CuN₄O₁₂S₂
• 分子量: 787.112
• InChiKey: SPMYFZQOICSPMI-UHFFFAOYSA-L

反应信息

• 作为产物：
  描述：

  copper(II) choride dihydrate 、 5-aminosulfonyl-4-chloro-2-((2-furanylmethyl)amino)benzoic acid hydrochloride 在 NaOH 作用下， 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  Synthesis, structural, spectral and EPR studies on the copper(II) complex of 5-(aminosulphonyl)-4-chloro-2-[(2-furanylmethyl)amino]benzoic acid (Furosemide)

  摘要：

  The copper(II) complexes of Furosemide (Fu) widely used as a diuretic were synthesized and isolated from aqueous and methanol solutions as CuFu2.2Solv and characterized by elemental analysis, single crystal X-ray diffraction, UV-vis and IR spectroscopy, EPR and magnetic susceptibility measurements. The complex CuFU2. 2MeOH was isolated from methanol solutions as green crystals. Its structure consists of flattened molecules arranged in stacks. A centrosymmetric CuO6 elongated bipyramid is formed around copper(II) by four oxygens from the COO- groups and two from the MeOH. The COO- groups act as bridges between the copper(II) atoms with two oxygens in the equatorial plane (Cu-O distance of 1.924 angstrom) and the other two in apical positions at 2.720 angstrom. The methanol oxygens are at an intermediate distance of 1.941 angstrom. The Cu-Cu separation is 4.749 angstrom. Hydrogen bonding occurs within and between the molecules.

  DOI：

  10.1016/s0277-5387(00)83747-x