1-(i-propyl)-3-(N-(2,6-di-i-propylphenylacetamido))imidazolium chloride | 1025468-11-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(i-propyl)-3-(N-(2,6-di-i-propylphenylacetamido))imidazolium chloride
• 英文别名: 1-(isopropyl)-3-(N-(2,6-diisopropylphenylacetamido))imidazolium chloride
• CAS: 1025468-11-4
• 化学式: C₂₀H₃₀N₃O*Cl
• 分子量: 363.931
• InChiKey: XHAAQOBYXQVCOR-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  1-(i-propyl)-3-(N-(2,6-di-i-propylphenylacetamido))imidazolium chloride 以 二氯甲烷 为溶剂， 生成 bis[1-(i-propyl)-3-(N-(2,6-di-i-propylphenylacetamido)imidazol-2-ylidene)]digold(I)
  参考文献：
  名称：

  通过调节酰胺基官能化的N-杂环卡宾（NHC）配体的N-取代基，从大型的12元大环化合物到金和银的离子（NHC）2M + Cl-型络合物。

  摘要：

  通过对N取代基进行适当的修饰，已经制备了一系列结构多样的金和银配合物，从离子（NHC）2M（+）Cl（-）（M = Au，Ag）型配合物扩展为大型12元大环杂环。酰胺基官能化的N-杂环卡宾。具体而言，离子型[1-（R）-3- {N-（叔丁基乙酰胺基）咪唑-2-亚乙基}] 2M（+）Cl（-），（R ＝ t-Bu，i-Pr； M在酰胺基官能化侧臂的N-叔丁基取代基和12元大环金属环[1-（R）-3- {N在以下情况下，得到-（（2，6-二异丙基苯基乙酰胺基）咪唑-2-亚基}] 2M2，（R ＝ t-Bu，i-Pr； M ＝ Au，Ag； 3b，3c，4b，4c）。 2，6-二异丙基苯基N-取代基。但是，这些结构多样的金和银的配合物是 采用常见的合成途径制备，该过程涉及氯化咪唑鎓盐（1a，2a，3a，4a）与Ag2O的反应，从而生成银络合物（1b，2b，3b，4b），当用（SMe2）AuCl处

  DOI：

  10.1021/ic702186g

文献信息

• Copper-free and amine-free Sonogashira coupling in air in a mixed aqueous medium by palladium complexes of N/O-functionalized N-heterocyclic carbenes
  作者：Manoja K. Samantaray、Mobin M. Shaikh、Prasenjit Ghosh

  DOI：10.1016/j.jorganchem.2009.06.026

  日期：2009.10

  Highly convenient copper-free and amine-free Sonogashira coupling of aryl bromides and iodides with terminal acetylenes under amenable conditions in air and in a mixed aqueous medium are reported using several new, user friendly and robust palladium precatalysts (1–5) of N/O-functionalized N-heterocyclic carbenes (NHCs). In particular, the precatalysts, 1 and 2, were synthesized from the imidazolium

  非常方便的铜-自由和芳基溴化物，并用在空气中适合的条件下终端炔碘化物的Sonogashira偶联和在混合的含水介质中使用的几种新的，用户友好的和健壮的钯预催化剂（报道不含胺的1 - 5）的ñ / O-官能化的N-杂环卡宾（NHCs）。特别地，所述预催化剂，1和2中，从咪唑鎓氯化物盐通过处理用合成的PdCl 2在吡啶中的K存在2 CO 3作为碱，而预催化剂，3 - 5通过用（COD）PdCl 2处理，由相应的银络合物合成α，β 。在DFT的研究上进行1 - 5络合物建议深埋NHC -钯σ结合分子轨道（MOS），该账户为金属-碳烯键的惰性性质的所产生强NHC -钯σ-相互作用的存在并提供有关这些预催化剂优异稳定性的见解。
• Rare [(NHC)₂Ni-OH]-Type Terminal Nickel Hydroxo and [(NHC)₂Ni]-Type Complexes of <i>N</i>/<i>O</i>-Functionalized N-Heterocyclic Carbenes as Precatalysts for Highly Desirable Base-Free Michael Reactions in Air at Ambient Temperature
  作者：Manoja K. Samantaray、Mobin M. Shaikh、Prasenjit Ghosh

  DOI：10.1021/om801186f

  日期：2009.4.13

  Highly convenient base-free Michael reaction of beta-dicarbonyl, beta-keto ester, and alpha-cyano ester compounds with activated ethylene compounds in air at ambient temperature catalyzed by a series of new nickel complexes, 1b-4b, of N/O-functionalized N-heterocyclic carbenes (NHC) are reported. Quite interestingly, of these nickel complexes, 1b and 2b were found to be of the [(NHC)(2)Ni-OH] type bearing a terminal [Ni-OH] moiety and are among the few known structurally characterized examples of monomeric terminal [Ni-OH] complexes. Compounds 3b and 4b, on the other hand, were found to be of the commonly encountered [(NHC)(2)Ni]-type complexes. More significantly, both the [(NHC)(2)Ni-OH] -type complexes 1b and 2b and the [(NHC)(2)Ni]-type complexes 3b and 4b were synthesized using same synthetic methodology by sheer modulation of the N-substituents on the N-heterocyclic carbene ring by the reaction of the imidazolium chloride salts with NiCl2 center dot 6H(2)O in the presence of K2CO3 as a base.