25(R)-3-oxo-24-methylenecycloartan-26-ol | 232266-06-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 25(R)-3-oxo-24-methylenecycloartan-26-ol
• 英文别名: 9,19-Cyclolanostan-3-one, 26-hydroxy-24-methylene-, (25R)-；(1S,3R,8R,11S,12S,15R,16R)-15-[(2R,6R)-7-hydroxy-6-methyl-5-methylideneheptan-2-yl]-7,7,12,16-tetramethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-one
• CAS: 232266-06-7
• 化学式: C₃₁H₅₀O₂
• 分子量: 454.737
• InChiKey: OKILVWSNJYSCMZ-XZTCGNEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  25(R)-3-oxo-24-methylenecycloartan-26-ol 在 chromium(VI) oxide 、 水 、 溶剂黄146 作用下， 以 苯 为溶剂， 反应 3.0h， 以20 mg的产率得到ambonic acid
  参考文献：
  名称：

  Triterpenoids from Mangifera indicafn1fn1Part iii in the series Triterpenoids from Mangifera indica. For part ii see Anjaneyulu et al., 1989.

  摘要：

  Two new triterpenoids, 25(R)-3-oxo-24-methylene cycloartan-26-ol and psi-taraxastanonol have been isolated from the neutral fraction of the stem-bark of Mangifera indica (var/cv sarikhas). The acidic fraction of the same extract yielded three new tetracyclic triterpenoids, 3-oxo-23(R or S)-hydroxy cycloart-24-en-26-oic acid and both C-23 epimers of 3 beta,23-dihydroxy cycloart-24-en-26-oic acid. The structures were elucidated by spectroscopic and chemical methods. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(98)00656-6

文献信息

• Triterpenoids from Mangifera indicafn1fn1Part iii in the series Triterpenoids from Mangifera indica. For part ii see Anjaneyulu et al., 1989.
  作者：V Anjaneyulu、P Satyanarayana、K.N Viswanadham、V.G Jyothi、K.Nageswara Rao、P Radhika

  DOI：10.1016/s0031-9422(98)00656-6

  日期：1999.4

  Two new triterpenoids, 25(R)-3-oxo-24-methylene cycloartan-26-ol and psi-taraxastanonol have been isolated from the neutral fraction of the stem-bark of Mangifera indica (var/cv sarikhas). The acidic fraction of the same extract yielded three new tetracyclic triterpenoids, 3-oxo-23(R or S)-hydroxy cycloart-24-en-26-oic acid and both C-23 epimers of 3 beta,23-dihydroxy cycloart-24-en-26-oic acid. The structures were elucidated by spectroscopic and chemical methods. (C) 1999 Elsevier Science Ltd. All rights reserved.