2-hydroxy-3-(((2-pyridylmethaneyl)azanylidene)methyl)benzoic acid | 159663-65-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-hydroxy-3-(((2-pyridylmethaneyl)azanylidene)methyl)benzoic acid
• 英文别名: 2-hydroxy-3-(((2-pyridylmethyl)azanylidene)methyl)benzoic acid；2-Hydroxy-3-(pyridin-2-ylmethyliminomethyl)benzoic acid
• CAS: 159663-65-7
• 化学式: C₁₄H₁₂N₂O₃
• 分子量: 256.261
• InChiKey: RHIRXWPNULNZIE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  82.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-hydroxy-3-(((2-pyridylmethaneyl)azanylidene)methyl)benzoic acid 、 copper(II) perchlorate 以 水 为溶剂， 以72%的产率得到
  参考文献：
  名称：

  A Synthetic Approach Towards Homotrinuclear Complexes: Design of Mn(II), Ni(II) AND Cu(II) Trinuclear Complexes Using Two New Unsymmetrical Tetradentate Ligands Derived from 3-Formylsalicylic Acid

  摘要：

  Two new polydentate ligands able to generate homotrinuclear complexes have been synthesized: 3-(N-(2-pyridylmethyl)formimidoyl)salicylic acid (H(2)fsaamp), 1, and 3-(N-(N',N'-dimethylaminoethyl)formimidoyl)salicylic acid, H(2)fsadme, 2. The synthetic process is as follows: the reaction of 3-formylsalicylic acid, H(2)fsa, with 2-(aminomethyl)pyridine and (N,N-dimethyl)ethylenediamine, respectively, leads to the Schiff bases H(2)fsaamp and H(2)fsadme. The two ligands have been characterized by chemical analyses, IR and H-1 NMR spectroscopy. The reaction of these ligands with Mn(II), Cu(II) and Ni(II) perchlorates yields trinuclear complexes: Ni-3(fsaamp)(2)(H2O)(4)(ClO4)(2) (3), Cu-3(fsaamp)(2)(H2O)(2)(ClO4)(2) (4), Mn-3(fsadme)(2)(H2O)(4)(ClO4)(2) (5) and Cu-3(fsadme)(2)(ClO4)(2) (6), which have been characterized by means of chemical analyses and spectroscopic methods. The magnetic data are in agreement with the presence of three paramagnetic centers within the homotrinuclear species.

  DOI：

  10.1080/00945719809351650