3-(dipropylaminomethyl)benzene-1,2-diol | 322648-99-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 3-(dipropylaminomethyl)benzene-1,2-diol
• 英文别名: 3-[(Dipropylamino)methyl]benzene-1,2-diol
• CAS: 322648-99-7
• 化学式: C₁₃H₂₁NO₂
• 分子量: 223.315
• InChiKey: FMZSPMMPOMJSFX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  43.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-(dipropylaminomethyl)benzene-1,2-diol 在 硅酸四乙酯 作用下， 以 乙醇 为溶剂， 以49%的产率得到[3-(N,N-dipropylaminomethyl)catecholato(2-)]bis[3-(N,N-dipropylammmoniomethyl)catecholato(2-)]silicate(IV)
  参考文献：
  名称：

  摘要：

  This paper reports the synthesis and characterization of a number of novel silicon(IV) complexes with a range of mono-Mannich bases of benzene-1,2-diol. Mannich bases of general structure 3-(dialkylaminomethyl) benzene-1,2-diol form zwitterionic 6-coordinate tris complexes with silicon(IV), eliminating the need for an external counter ion. These complexes exhibit marked differences in their ability to partition between an aqueous and organic phase compared with the analogous tris(benzene-1,2-diol) silicon(IV) complex. Mannich bases of diamines and benzene-1, 2-diol will also complex to silicon; however, they result in more complicated polymeric structures.

  DOI：

  10.1071/ch01064
• 作为产物：
  描述：

  木榴油 在 氢溴酸 作用下， 以 乙醇 、 溶剂黄146 为溶剂， 反应 120.0h， 生成 3-(dipropylaminomethyl)benzene-1,2-diol
  参考文献：
  名称：

  摘要：

  The synthesis of a number of novel dibenzene-1,2-diol Mannich bases can be achieved in good yields by the condensation of 2-methoxyphenol, formaldehyde and secondary diamines. The newly developed synthetic method utilizes 2-methoxyphenol instead of benzene-1,2-diol providing a useful tool for greater control over reaction products.

  DOI：

  10.1071/ch00079

文献信息

• ——
  作者：Marcus J. Caulfield、Tiziana Russo、David H. Solomon

  DOI：10.1071/ch00079

  日期：——

  The synthesis of a number of novel dibenzene-1,2-diol Mannich bases can be achieved in good yields by the condensation of 2-methoxyphenol, formaldehyde and secondary diamines. The newly developed synthetic method utilizes 2-methoxyphenol instead of benzene-1,2-diol providing a useful tool for greater control over reaction products.
• ——
  作者：Marcus J. Caulfield、Tiziana Russo、David H. Solomon

  DOI：10.1071/ch01064

  日期：——

  This paper reports the synthesis and characterization of a number of novel silicon(IV) complexes with a range of mono-Mannich bases of benzene-1,2-diol. Mannich bases of general structure 3-(dialkylaminomethyl) benzene-1,2-diol form zwitterionic 6-coordinate tris complexes with silicon(IV), eliminating the need for an external counter ion. These complexes exhibit marked differences in their ability to partition between an aqueous and organic phase compared with the analogous tris(benzene-1,2-diol) silicon(IV) complex. Mannich bases of diamines and benzene-1, 2-diol will also complex to silicon; however, they result in more complicated polymeric structures.