2,4,4-trimethyl-4,5-dihydro-[1,3]oxazin-6-one | 53121-04-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环化合物
• 英文名称: 2,4,4-trimethyl-4,5-dihydro-[1,3]oxazin-6-one
• 英文别名: 2,4,4-trimethyl-5H-1,3-oxazin-6-one
• CAS: 53121-04-3
• 化学式: C₇H₁₁NO₂
• 分子量: 141.17
• InChiKey: ZMYZRUSTDGPOQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-acetylamino-3-methyl-butyric acid 在 N,N'-二环己基碳二亚胺 作用下， 生成 2,4,4-trimethyl-4,5-dihydro-[1,3]oxazin-6-one
  参考文献：
  名称：

  Black,D.S.C.; Boscacci,A.B., Australian Journal of Chemistry, 1977, vol. 30, p. 1109 - 1116

  摘要：

  DOI：

文献信息

• POROUS POLYMERIC RESINS
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US20140193875A1

  公开（公告）日：2014-07-10

  Porous polymeric resins, reaction mixtures and methods that can be used to prepare the porous polymeric resins, and uses of the porous polymeric resin are described. More specifically, the polymeric resins typically have a hierarchical porous structure plus reactive groups that can be used to interact with or react with a variety of different target compounds. The reactive groups can be selected from an acidic group or a salt thereof, an amino group or salt thereof, a hydroxyl group, an azlactone group, a glycidyl group, or a combination thereof.
• HYDROPHILIZED CARBOSILOXANE VINYLIC MONOMERS
  申请人：Novartis AG

  公开号：US20150309210A1

  公开（公告）日：2015-10-29

  The invention provides a hydrophilized carbosiloxane vinylic monomer which comprises (1) a poly(carbosiloxane) segment, (2) one sole ethylenically unsaturated group, and (3) at least one terminal or pendant group which is a hydrophilic group or hydrophilic polymer chain. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from a hydrophilized carbosiloxane vinylic monomer of the invention.
• POLY(OXAZOLINE-CO-ETHYLENEIMINE)-EPICHLOROHYDRIN COPOLYMERS AND USES THEREOF
  申请人：Novartis AG

  公开号：US20160061995A1

  公开（公告）日：2016-03-03

  The invention is related to poly(2-oxazoline-co-ethyleneimine)-epichlorohydrin copolymers and chemically-modified derivatives thereof as well as their uses in formation of non-silicone hydrogel coatings on silicone hydrogel contact lenses.
• METHOD FOR APPLYING STABLE COATING ON SILICONE HYDROGEL CONTACT LENSES
  申请人：Novartis AG

  公开号：US20160062142A1

  公开（公告）日：2016-03-03

  The invention is related to a method for producing silicone hydrogel contact lenses with having a stable coating thereon. A method of the invention comprises a water-based coating process (step) for forming a relatively-stable base coating of a homo- or copolymer of acrylic acid or C 1 -C 3 alkylacrylic acid onto a silicone hydrogel contact lens made from a lens formulation comprising from about 35% to about 60% by weight of N-vinylpyrrolidone.
• METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON
  申请人：Novartis AG

  公开号：US20160326046A1

  公开（公告）日：2016-11-10

  The invention is related to a method for producing silicone hydrogel contact lenses with having a stable coating thereon. A method of the invention comprises a water-based coating process (step) for forming a relatively-stable base coating of a homo- or copolymer of acrylic acid or C 1 -C 3 alkylacrylic acid onto a silicone hydrogel contact lens made from a lens formulation comprising from about 35% to about 60% by weight of N-vinylpyrrolidone.