1,1,1-trifluoro-N-[fluoro-(4-methylphenyl)-oxo-λ6-sulfanylidene]methanesulfonamide | 156427-85-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1,1-trifluoro-N-[fluoro-(4-methylphenyl)-oxo-λ6-sulfanylidene]methanesulfonamide
• CAS: 156427-85-9
• 化学式: C₈H₇F₄NO₃S₂
• 分子量: 305.274
• InChiKey: SSBVGYCFRQHYHQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  80.3
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  1,1,1-trifluoro-N-[fluoro-(4-methylphenyl)-oxo-λ6-sulfanylidene]methanesulfonamide 在 硫酸 、 氨 作用下， 生成 N-[amino-(4-methylphenyl)-oxo-lambda6-sulfanylidene]-1,1,1-trifluoromethanesulfonamide
  参考文献：
  名称：

  The unusual reactivity of the mono- and bis- N-(trifluoromethylsulfonyl)-substituted azaanalogs of arenesulfonochlorides

  摘要：

  The reactions of N-(trifluoromethylsulfonyl)arenesulfonimidoyl- and N, N'- bis(trifluoromethylsulfonyl)arenesulfonodiimidoyl chlorides of general formulas Ar-S(0)(=NSO2CF3)Cl (1) and Ar-S(=NSO2CF3)(2)Cl (2) with ammonia have been investigated and found to yield the ammonium salts of [N-(trifluoromethylsulfonyl)arenesulfinylimino]-N' (trifluoromethylsulfonyl)amides. The high oxidative ability of the chlorides (1,2) have been shown. Thus, chlorides (2) react with benzene or trifluoromethylbenzene, to form the chlorobenzene or 3-chloro- trifluoromethylbenzene. The fluorides of the general formulas Ar-S(0)(=NSO2CF3)F and Ar-S(=NSO2CF3)(2)F have been prepared. Their interaction with ammonia leads to the usual formation of corresponding amides. The electron nature of new electron withdrawing substituents have been investigated.

  DOI：

  10.1016/s0040-4020(01)81341-7
• 作为产物：
  描述：

  N-[chloro-(4-methylphenyl)-oxo-lambda6-sulfanylidene]-1,1,1-trifluoromethanesulfonamide 在 dichlorotrifluoromethanesulfonamide 、 三氟化锑 作用下， 反应 0.05h， 生成 1,1,1-trifluoro-N-[fluoro-(4-methylphenyl)-oxo-λ6-sulfanylidene]methanesulfonamide
  参考文献：
  名称：

  The unusual reactivity of the mono- and bis- N-(trifluoromethylsulfonyl)-substituted azaanalogs of arenesulfonochlorides

  摘要：

  The reactions of N-(trifluoromethylsulfonyl)arenesulfonimidoyl- and N, N'- bis(trifluoromethylsulfonyl)arenesulfonodiimidoyl chlorides of general formulas Ar-S(0)(=NSO2CF3)Cl (1) and Ar-S(=NSO2CF3)(2)Cl (2) with ammonia have been investigated and found to yield the ammonium salts of [N-(trifluoromethylsulfonyl)arenesulfinylimino]-N' (trifluoromethylsulfonyl)amides. The high oxidative ability of the chlorides (1,2) have been shown. Thus, chlorides (2) react with benzene or trifluoromethylbenzene, to form the chlorobenzene or 3-chloro- trifluoromethylbenzene. The fluorides of the general formulas Ar-S(0)(=NSO2CF3)F and Ar-S(=NSO2CF3)(2)F have been prepared. Their interaction with ammonia leads to the usual formation of corresponding amides. The electron nature of new electron withdrawing substituents have been investigated.

  DOI：

  10.1016/s0040-4020(01)81341-7

文献信息

• Garlyauskajte Romute Yu., Sereda Sergej V., Yagupolskii Lev M., Tetrahedron, 50 (1994) N 23, S 6891-6906
  作者：Garlyauskajte Romute Yu., Sereda Sergej V., Yagupolskii Lev M.

  DOI：——

  日期：——