3-(4-Bromophenoxy)benzyl bromide | 65295-59-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(4-Bromophenoxy)benzyl bromide
• 英文别名: 1-bromo-4-[3-(bromomethyl)phenoxy]benzene
• CAS: 65295-59-2
• 化学式: C₁₃H₁₀Br₂O
• 分子量: 342.03
• InChiKey: UUMSCQXCUFAGRY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (RS)-1,1,1-trifluoro-2-(4-ethoxyphenyl)propan-3-ol 、 3-(4-Bromophenoxy)benzyl bromide 生成 1,1,1-Trifluoro-2-(4-ethoxyphenyl)-3-(3-(4-bromophenoxy)benzyloxy)propane
  参考文献：
  名称：

  BUSHELL, MICHAEL JOHN;WHITTLE, ALAN JOHN;CARR, ROBIN ARTHUR ELLIS

  摘要：

  DOI：
• 作为产物：
  描述：

  (3-(4-bromophenoxy)phenyl)methanol 在 phosphorus tribromide 作用下， 生成 3-(4-Bromophenoxy)benzyl bromide
  参考文献：
  名称：

  Insecticidal ethers

  摘要：

  这项发明涉及新型氟化醚，可用作杀虫剂和杀螨剂，涉及其制备的工艺和中间体，涉及其杀虫和杀螨组合物，以及用于 bekämpfung 和控制昆虫和螨虫害的方法。

  公开号：

  US05225607A1

文献信息

• 2-Arylpropyl ether or thioether derivatives and insecticidal and
  申请人：Mitsuitoatsu Chemicals Inc.

  公开号：US04397864A1

  公开（公告）日：1983-08-09

  The present invention relates to 2-arylpropyl ether or thioether derivatives represented by the following general formula [I]: ##STR1## wherein Ar stands for an aryl group, R stands for a methyl or ethyl group, Y stands for an oxygen or sulfur atom, and B stands for a group represented by the following formula [II]: ##STR2## or the following general formula [III]: ##STR3## wherein Z stands for an oxygen or sulfur atom or a carbonyl or methylene group, R.sup.1 stands for a hydrogen or halogen atom or a lower alkyl group or a lower alkoxy group, and n is an integer of from 1 to 5 with the proviso that when n is 2 or more, the groups R.sup.1 may be the same or different, and also to processes for the preparation or these ethers of thioethers and a use of these ethers or thioethers. These compounds of the present invention have excellent insecticidal and acaricidal activities while the toxicity of these compounds are very low.

  本发明涉及由以下一般式[I]表示的2-芳基丙基醚或硫醚衍生物：其中Ar代表芳基，R代表甲基或乙基，Y代表氧原子或硫原子，B代表由以下式[I]或以下一般式[III]表示的基团：其中Z代表氧原子或硫原子或羰基或亚甲基基团，R1代表氢原子或卤素原子或较低烷基基团或较低烷氧基团，n是1至5的整数，但当n为2或更多时，基团R1可以相同或不同，并且本发明还涉及制备这些醚或硫醚的方法以及这些醚或硫醚的用途。这些本发明的化合物具有出色的杀虫和杀螨活性，同时这些化合物的毒性非常低。
• Process for the preparation of 2-arylpropyl ether or thioether
  申请人：Mitsuitoatsu Chemicals Inc.

  公开号：US04570005A1

  公开（公告）日：1986-02-11

  2-Arylpropyl ether or thioether derivatives represented by the following general formula [I]: ##STR1## wherein Ar stands for an aryl group, R stands for a methyl or ethyl group, Y stands for an oxygen or sulfur atom, and B stands for a group represented by the following formula [II]: ##STR2## or the following general formula [III]: ##STR3## wherein Z stands for an oxygen or sulfur atom or a carbonyl or methylene group, R.sup.1 stands for a hydrogen or halogen atom or a lower alkyl group or a lower alkoxy group, and n is an integer of from 1 to 5 with the proviso that when n is 2 or more, the groups R.sup.1 may be the same or different, are produced by reacting a compound represented by the following formula (V): ##STR4## with a compound represented by the following formula (VI): B--CH.sub.2 --D (VI) wherein Ar, R and B are defined above, A is a halogen atom and D is Y--H in which Y is as defined above, in the presence of a base in dimethylsulfoxide or sulfolane. The compounds thus prepared have excellent insecticidal and acaricidal activities while the toxicity of these compounds are very low.

  以下是2-芳基丙基醚或硫醚衍生物的通式[I]：##STR1##其中Ar代表芳基，R代表甲基或乙基，Y代表氧原子或硫原子，B代表以下通式[II]所代表的基团：##STR2##或以下通式[III]的通式：##STR3##其中Z代表氧原子或硫原子或羰基或亚甲基基团，R.sup.1代表氢原子或卤素原子或较低的烷基基团或较低的烷氧基基团，n是1到5之间的整数，但当n为2或更多时，基团R.sup.1可以相同或不同。这些衍生物是通过将以下通式(V)所代表的化合物与以下通式(VI)所代表的化合物反应而制备的：##STR4##其中Ar，R和B如上所定义，A是卤素原子，D是Y-H，其中Y如上所定义，在二甲基亚砜或硫代乙醇中，在碱的存在下。这样制备的化合物具有优异的杀虫和杀螨活性，而这些化合物的毒性非常低。
• Novel ether compound, a process for manufacturing the same, a
  申请人：Sumitomo Chemical Company, Limited

  公开号：US04840971A1

  公开（公告）日：1989-06-20

  An ether compound represented by the following general formula (I), its produciton method and an insecticidal and/or acaricidal composition containing it as an active ingredient: ##STR1## wherein R.sub.1 and R.sub.2, which may be identical or different, represent a hydrogen or halogen atom or a lower alkyl, lower haloalkyl, lower alkoxyl, lower haloalkoxyl, lower alkenyl or lower alkenyloxyl group, or represent, taken together, methylenedioxy, lower alkylene, ethyleneoxy or lower alkylethyleneoxy group; R.sub.3 represents a hydrogen or fluorine atom; R.sub.4 represents a hydrogen or halogen atom or a lower alkyl, lower haloalkyl, lower alkoxyl or lower haloalkoxyl group; m represents an integer of 1 or 2; Y represents an oxygen or sulfur atom or a group represented by the formula --CH.sub.2 -- or --NH--; and Z represents a nitrogen atom or a group represented by the formula --CH.dbd., and its starting materials.

  由以下一般式(I)表示的醚类化合物，其生产方法以及含有其作为活性成分的杀虫和/或杀螨组合物： ##STR1## 其中，R.sub.1和R.sub.2可以相同或不同，表示氢或卤素原子或较低的烷基，较低的卤代烷基，较低的烷氧基，较低的卤代烷氧基，较低的烯基或较低的烯氧基基团，或表示一起取的亚甲二氧基，较低的烷基，乙烯氧基或较低的烷基乙烯氧基基团；R.sub.3表示氢或氟原子；R.sub.4表示氢或卤素原子或较低的烷基，较低的卤代烷基，较低的烷氧基或较低的卤代烷氧基基团；m表示1或2的整数；Y表示氧或硫原子或由公式--CH.sub.2--或--NH--表示的基团；Z表示氮原子或由公式--CH.dbd.表示的基团，以及其起始材料。
• Ether compounds, their production and an insecticidal and/or acaricidal composition containing the same
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0094085A1

  公开（公告）日：1983-11-16

  Ether compounds of the general formula, wherein W represents methine group or nitrogen atom, and (1) when W is the methine group, R1 represents hydrogen atom, fluorine atom, chlorine atom, bromine atom or methyl group, R2 represents hydrogen atom or fluorine atom, R3 and R4 are same or different and represent hydrogen atom, a halogen atom, a C1-4 alkyl, a C1-4 alkoxyl, difluoromethoxy or 2,2,2-trifluoroethoxy group, or represent, taken together, methylenedioxy group, A represents I oxygen atom, methylene group or imino group, and when the A represents oxygen atom or methylene group, X and Y represent, taken together, ethylene group or 1,1-difluoroethylene group and when the A represents imino group, both X and Y represent methyl group or represent, taken together, ethylene j group or 1,1-difluoroethylene group, and (2) when W is the nitrogen atom, both R1 and R2 represent hydrogen atom, R3 and R4 are as defined above, A represents oxygen atom, and both X and Y represent methyl group or represent, taken together, ethylene group or 1,1-difluoroethylene group. The ether compounds of the present invention are useful as an active ingredient of an insecticidal and/or acaricidal composition.

  通式如下的醚化合物 其中 W 代表甲基或氮原子，(1) 当 W 为甲基时、 R1 代表氢原子、氟原子、氯原子、溴原子或甲基，R2 代表氢原子或氟原子，R3 和 R4 相同或不同并代表氢原子、卤素原子、C1-4 烷基、C1-4 烷氧基、二氟甲氧基或 2,2,2-三氟乙氧基，或共同代表亚甲二氧基，A 代表 I 氧原子、亚甲基或亚氨基，当 A 代表氧原子或亚甲基时，X 和 Y 代表、(2) 当 W 为氮原子时，R1 和 R2 均代表氢原子，R3 和 R4 如上定义，A 代表氧原子，X 和 Y 均代表甲基或代表乙烯基或 1，1-二氟乙烯基。 本发明的醚化合物可用作杀虫和/或杀螨剂组合物的活性成分。
• Ether compounds, process for their preparation, compositions containing the same and use thereof
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0240978A2

  公开（公告）日：1987-10-14

  Ether compounds represented by the following general formula (I), their production and insecticidal and/or acaricidal compositions containing it as an active ingredient: wherein R, and R2, which may be identical or different, represent a hydrogen or halogen atom or a lower alkyl, lower haloalkyl, lower alkoxyl, lower haloalkoxyl, lower alkenyl or lower alkenyloxyl group, or represent, taken together, methylenedioxy, lower alkylene, ethyleneoxy or lower alkylethyleneoxy group; R3 represents a hydrogen or fluorine atom; R4 represents a hydrogen or halogen atom or a lower alkyl, lower haloalkyl, lower alkoxyl or lower haloalkoxyl group; m represents an integer of 1 or 2; Y represents an oxygen or sulfur atom or a group represented by the formula -CH2-or -NH-; and Z represents a nitrogen atom or a group represented by the formula -CH =, and starting materials.

  由以下通式(I)代表的醚类化合物、其生产以及含有该化合物作为活性成分的杀虫和/或杀螨剂组合物： 其中，R 和 R2（可以相同或不同）代表氢原子或卤素原子或低级烷基、低级卤代烷基、低级烷氧基、低级卤代烷氧基、低级烯基或低级烯酰氧基，或同时代表亚甲基二氧基、低级亚烷基、亚乙基氧基或低级亚烷基乙氧基；R3 代表氢原子或氟原子；R4 代表氢原子或卤素原子或低级烷基、低级卤代烷基、低级烷氧基或低级卤代烷氧基；m 代表 1 或 2 的整数；Y 代表氧原子或硫原子或由式 -CH2- 或 -NH- 代表的基团；Z 代表氮原子或由式 -CH = 代表的基团，以及起始原料。