S-(4-methylthiobenzoyl)thioglycolic acid ethyl ester | 129841-39-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: S-(4-methylthiobenzoyl)thioglycolic acid ethyl ester
• 英文别名: ethyl 2-(4-methylbenzenecarbothioyl)sulfanylacetate
• CAS: 129841-39-0
• 化学式: C₁₂H₁₄O₂S₂
• 分子量: 254.374
• InChiKey: XCKFNVMTGRYSPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  83.7
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  S-(4-methylthiobenzoyl)thioglycolic acid ethyl ester 、 4-甲氧基苯基 异硫氰酸酯 、 碘甲烷 生成 4-Methyl-dithiobenzoic acid 1-(4-methoxy-phenyl)-4-methylsulfanyl-2-oxo-1,2-dihydro-azet-3-yl ester
  参考文献：
  名称：

  Doelling, Wolfgang; Vogt, Almut; Sperk, Katrin, Synthesis, 1990, # 7, p. 621 - 623

  摘要：

  DOI：

文献信息

• Cell culture medium and process for protein expression, said medium and process comprising a PAM inhibitor
  申请人：SANDOZ GMBH

  公开号：EP2450375A1

  公开（公告）日：2012-05-09

  The present invention is related to a cell culture medium for the expression of a protein, which medium comprises a PAM inhibitor, or a physiological equivalent thereof, and to a cell culture process for the expression of a protein, in which process a PAM inhibitor, or a physiological equivalent thereof, is used (Fig. 1).

  本发明涉及一种用于表达蛋白质的细胞培养基，该培养基包含 PAM 抑制剂或其生理等效物；本发明还涉及一种用于表达蛋白质的细胞培养过程，在该过程中使用了 PAM 抑制剂或其生理等效物（图 1）。
• DOLLING, WOLFGANG;VOGT, ALMUT;SPERK, KATRIN;AUGUSTIN, MANFRED, SYNTHESIS (BRD),(1990) N, C. 621-623
  作者：DOLLING, WOLFGANG、VOGT, ALMUT、SPERK, KATRIN、AUGUSTIN, MANFRED

  DOI：——

  日期：——
• CELL CULTURE MEDIUM AND PROCESS FOR PROTEIN EXPRESSION, SAID MEDIUM AND PROCESS COMPRISING A PAM INHIBITOR
  申请人：SANDOZ GMBH

  公开号：EP2638064B1

  公开（公告）日：2021-07-21
• Cell Culture Medium And Process For Protein Expression, Said Medium And Process Comprising A Pam Inhibitor
  申请人：SANDOZ GMBH

  公开号：US20150267238A1

  公开（公告）日：2015-09-24

  The present invention is related to a cell culture medium for the expression of a protein, which medium comprises a PAM inhibitor, or a physiological equivalent thereof, and to a cell culture process for the expression of a protein, in which process a PAM inhibitor, or a physiological equivalent thereof, is used (FIG. 1 ).
• US9062337B2
  申请人：——

  公开号：US9062337B2

  公开（公告）日：2015-06-23