N-dichloroacetyl-4-ethyl-1,3-oxazolidine | 52836-86-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: N-dichloroacetyl-4-ethyl-1,3-oxazolidine
• 英文别名: 3-dichloroacetyl-4-ethyl-oxazolidine；2,2-Dichloro-1-(4-ethyl-1,3-oxazolidin-3-yl)ethan-1-one；2,2-dichloro-1-(4-ethyl-1,3-oxazolidin-3-yl)ethanone
• CAS: 52836-86-9
• 化学式: C₇H₁₁Cl₂NO₂
• 分子量: 212.076
• InChiKey: MCNAPBRXUMKCJP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  二氯乙酰氯 、 4-乙基恶唑烷 在 sodium hydroxide 作用下， 以 水 、 苯 为溶剂， 生成 N-dichloroacetyl-4-ethyl-1,3-oxazolidine
  参考文献：
  名称：

  A convenient synthesis of novelN-dichloroacetyl-1,3-oxazolidine

  摘要：

  Abstract magnified imageA short and efficient route of synthesis and structural characterization of a series of novel N‐dichloroacetyl‐1,3‐oxazolidine derivatives has been developed. These new compounds characterized of the disubstitution at position 2 by alkyl, cycloalkane, and phenyl were synthesized in good yields via a sequential procedure involving condensation and acylation. All the compounds are characterized by IR, 1H NMR, 13C NMR, and element analysis. J. Heterocyclic Chem., (2010).

  DOI：

  10.1002/jhet.289

文献信息

• A convenient synthesis of novel<i>N</i>-dichloroacetyl-1,3-oxazolidine
  作者：Fei Ye、Lei Yang、Haitao Li、Ying Fu、Weijun Xu

  DOI：10.1002/jhet.289

  日期：——

  Abstract magnified imageA short and efficient route of synthesis and structural characterization of a series of novel N‐dichloroacetyl‐1,3‐oxazolidine derivatives has been developed. These new compounds characterized of the disubstitution at position 2 by alkyl, cycloalkane, and phenyl were synthesized in good yields via a sequential procedure involving condensation and acylation. All the compounds are characterized by IR, 1H NMR, 13C NMR, and element analysis. J. Heterocyclic Chem., (2010).