benzyl methyl adipate | 137195-65-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzyl methyl adipate
• 英文别名: 6-O-benzyl 1-O-methyl hexanedioate
• CAS: 137195-65-4
• 化学式: C₁₄H₁₈O₄
• 分子量: 250.295
• InChiKey: SVKQLWAVXRJVBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  重氮甲烷 、 己二酸单苄酯 以 二氯甲烷 为溶剂， 反应 0.5h， 生成 benzyl methyl adipate
  参考文献：
  名称：

  格鲁布斯卡宾配合物的非易位作用：从无氢还原α，β-不饱和烯烃到固体支持的连续交叉复分解/还原。

  摘要：

  使用非转移作用的Grubbs催化剂和Et（3）SiH，进行了高效且高产率的α，β-不饱和烯烃“无氢”还原反应。在微波辐射下优化条件。应用于固相有机合成可以通过顺序的交叉复分解/烯烃还原反应来轻松构建sp（3）-sp（3）碳键。

  DOI：

  10.1039/c0cc04115g

文献信息

• Relay Catalysis for Selective Aerobic Oxidative Esterification of Primary Alcohols with Methanol
  作者：Yibo Yu、Jie Lin、Anni Qin、Huanan Wang、Jie Wang、Weiyi Wang、Guolin Wu、Qian Zhang、Hui Qian、Shengming Ma

  DOI：10.1021/acs.orglett.4c01059

  日期：2024.4.26

  and ubiquitous in polymers, bioactive compounds, and natural products. Their traditional synthetic approach is the esterification of carboxylic acids or their activated derivatives with alcohols. Herein, a bimetallic relay catalytic protocol was developed for the aerobic esterification of one alcohol in the presence of a slowly oxidizing alcohol, which has been identified as methanol. A concise synthesis

  酯是大宗化学品和精细化学品，普遍存在于聚合物、生物活性化合物和天然产品中。他们的传统合成方法是羧酸或其活化衍生物与醇的酯化。在此，开发了一种双金属中继催化方案，用于在缓慢氧化的醇（已被鉴定为甲醇）存在下对一种醇进行有氧酯化。进行了邻苯酸的简明合成以证明该反应的实用性和潜力。
• TASHIRO, MASASHI;TSUZUKI, HIROHISA;GOTO, HIDEYUKI;OGASAHARA, SHOJI;MATAKA+, J. LABELL. COMPOUNDS AND RADIOPHARM., 28,(1990) N, C. 855-866
  作者：TASHIRO, MASASHI、TSUZUKI, HIROHISA、GOTO, HIDEYUKI、OGASAHARA, SHOJI、MATAKA+

  DOI：——

  日期：——
• MOLDED POLYURETHANE BODIES WITH EXCELLENT FLEXIBILITY AT LOW TEMPERATURE
  申请人：BASF SE

  公开号：US20180057650A1

  公开（公告）日：2018-03-01

  The present invention relates to a process for producing polyurethane moldings, wherein (a) organic polyisocyanates are mixed with (b) one or more compounds having at least two hydrogen atoms which are reactive toward isocyanate, comprising polyester polyol, (c) blowing agent, (d) catalyst, and (e) propylene carbonate and compounds selected from the group consisting of at least one compound of the general formula (I) and a compound of the formula (II), to give a reaction mixture, introduced into a mold and allowed to react to give a polyurethane molding. The present invention further relates to polyurethane moldings obtainable by such a process and also the use of these moldings as steering wheels, seats, armrests and in particular as shoe soles.
• The non-metathetic role of Grubbs' carbene complexes: from hydrogen-free reduction of α,β-unsaturated alkenes to solid-supported sequential cross-metathesis/reduction
  作者：Andrés A. Poeylaut-Palena、Sebastián A. Testero、Ernesto G. Mata

  DOI：10.1039/c0cc04115g

  日期：——

  An efficient and high-yielding "hydrogen-free" reduction of alpha,beta-unsaturated alkenes was carried out employing Grubbs' catalyst in a non-metathetic role and Et(3)SiH. Conditions were optimized under microwave irradiation. Application to the solid-phase organic synthesis allows a facile construction of sp(3)-sp(3) carbon bonds through a sequential cross metathesis/olefin reduction.

  使用非转移作用的Grubbs催化剂和Et（3）SiH，进行了高效且高产率的α，β-不饱和烯烃“无氢”还原反应。在微波辐射下优化条件。应用于固相有机合成可以通过顺序的交叉复分解/烯烃还原反应来轻松构建sp（3）-sp（3）碳键。