4-Pyridylthiolacetat | 36875-66-8

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 4-Pyridylthiolacetat
• 英文别名: 4-pyridyl thioacetate；S-Pyridin-4-yl ethanethioate
• CAS: 36875-66-8
• 化学式: C₇H₇NOS
• 分子量: 153.205
• InChiKey: GEVGAAAZQMTZTR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  55.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-(4-硫代-1(4H)-吡啶基)乙酮 生成 4-Pyridylthiolacetat
  参考文献：
  名称：

  JORDAN, F.;KUDZIN, Z.;WITCZAK, Z.;HOOPS, PH., J. ORG. CHEM., 1986, 51, N 4, 571-573

  摘要：

  DOI：

文献信息

• [EN] INSECT BEHAVIOUR MODIFYING COMPOUNDS<br/>[FR] COMPOSES DE MODIFICATION DU COMPORTEMENT D'INSECTES
  申请人：NZ INST FOR CROP & FOOD RES

  公开号：WO2005046330A1

  公开（公告）日：2005-05-26

  The invention provides methods for controlling thrips populations using thrips-repelling and/or thrips-attracting agents. The agents are derivatives of pyridine. The invention also provides methods of preventing or minimising damage to plants by use of the same.

  这项发明提供了利用驱避蓟马和/或吸引蓟马剂来控制蓟马种群的方法。这些剂是吡啶的衍生物。该发明还提供了利用相同剂来预防或减少植物受到的损害的方法。
• COLCHICINE DERIVATIVES
  申请人：——

  公开号：US20040204370A1

  公开（公告）日：2004-10-14

  Certain N-deacetylcolchicine and N-deacetylthiocolchine derivatives are described wherein the 7-N position on the B ring is substituted with the group —C(O)—(CHR 4 ) m -AR, wherein m is an integer of 0-10, A is S, O, N or a covalent bond; R 1 is substituted phenyl or substituted benzoyl; optionally substituted cycloalkyl of 3-7 carbons; optionally substituted naphtyl; an optionally substituted imide ring; an optionally substituted 5 or 6 member heterocycle with at least one N, S, or O in the ring; or an optionally substituted fused heterocyclic or fused carboxyclic ring system; R 2 (at the 2 -position of the A ring) is methoxy, hydroxy, or methylenedioxy when taken together with R 3 ; R 3 (at the 3 -position of the A ring) is methoxy, hydroxy, a monosaccharide radical, or is methylenedioxy when taken together with R 2 ; and R 4 is H or is H or methyl when m is 1. Also dimers of such compounds are disclosed. When combined with suitable pharmaceutical excipients, these compounds are useful for treating various types of cancer.

  描述了某些N-去乙酰基秋水仙碱和N-去乙酰基硫秋水仙碱衍生物，其中B环上的7-N位置被取代为基团—C(O)—(CHR4)m-AR，其中m为0-10的整数，A为S、O、N或共价键；R1为取代苯基或取代苯甲酰基；可选择取代的含有3-7个碳原子的环烷基；可选择取代的萘基；可选择取代的亚胺环；可选择取代的含有至少一个N、S或O的5或6元杂环；或可选择取代的融合杂环或融合环戊二酸环系统；R2（在A环的2位）为甲氧基、羟基或与R3一起时为亚甲二氧基；R3（在A环的3位）为甲氧基、羟基、单糖基团，或与R2一起时为亚甲二氧基；R4为H或在m为1时为H或甲基。此外，还公开了这些化合物的二聚体。与适当的药用辅料结合时，这些化合物可用于治疗各种类型的癌症。
• QUORUM SENSING ANTAGONIST, METHOD OF PREVENTING A BIOFILM FORMATION USING THE QUORUM SENSING ANTAGONIST AND METHOD OF REDUCING A BACTERIAL CONTAMINATION USING THE QUORUM SENSING ANTAGONIST
  申请人：Yoon Je-Yong

  公开号：US20100292261A1

  公开（公告）日：2010-11-18

  In the quorum sensing antagonist blocking the communication in bacteria, the method for preventing biofilm formation using this quorum sensing antagonist and the method for reducing the bacterial contamination, the quorum sensing antagonist contains the homoserine lactone moiety and sulfanylethanoyl group, and has a similar chemical structure to that of the autoinducer which is produced by bacteria as a signal, whereby the quorum sensing antagonist can inhibit the formation of biofilm and reduce the bacterial contamination as well.

  在细菌中，通过使用群体感应拮抗剂阻断通信的方法，可以防止生物膜的形成和减少细菌污染。这种群体感应拮抗剂含有同型半胱氨酸内酯基团和磺酰乙酰基团，并且具有类似于细菌产生的信号自诱导物的化学结构，从而可以抑制生物膜的形成和减少细菌污染。
• Podophyllotoxin derivatives
  申请人：Yang Li-Xi

  公开号：US20050004169A1

  公开（公告）日：2005-01-06

  4-O esters of podophyllotoxin and 4′-demethylepipodophyllotoxin are provided. The compounds are 4-O esters of an alkanoic acid or substituted alkanoic acid and podophyllotoxin and 4′-demethylepipodophyllotoxin. The compounds are useful for treating cancer.

  提供了Podophyllotoxin和4'-去甲基表皮Podophyllotoxin的4-O酯化物。这些化合物是Podophyllotoxin和4'-去甲基表皮Podophyllotoxin与烷基酸或取代烷基酸的4-O酯化物。这些化合物可用于治疗癌症。
• Insect Behaviour Modifying Compounds
  申请人：Davidson Melanie Millicent

  公开号：US20080241205A1

  公开（公告）日：2008-10-02

  The invention provides methods for controlling thrips populations using thrips-repelling and/or thrips-attracting agents. The invention also provides methods of preventing or minimising damage to plants by use of the same.

  本发明提供了使用驱避或吸引蓟马剂控制蓟马种群的方法。本发明还提供了使用相同方法预防或最小化对植物的损害的方法。