benzyltriethyl-ammonium hydrogen sulfate | 89039-87-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzyltriethyl-ammonium hydrogen sulfate
• 英文别名: Benzyl(triethyl)azanium;hydron;sulfate
• CAS: 89039-87-2
• 化学式: C₁₃H₂₂N*H*O₄S
• 分子量: 289.396
• InChiKey: MEPLDDAONLVHEF-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.84
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  85.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-chlorocyclohexyl-phenyl ketone 、 benzyltriethyl-ammonium hydrogen sulfate 在 氢氧化钾 作用下， 以 水 为溶剂， 生成 1-Hydroxy-cyclohexyl-phenyl ketone
  参考文献：
  名称：

  Process for producing 1-hydroxy ketones

  摘要：

  该发明涉及一种生产I式化合物的新工艺，其中R1例如为苯基，而R2和R3例如为环己基。应用相转移催化方法，在水的存在下，将式II化合物与羟基离子反应，特别是与碱金属羟基或碱土金属羟基反应。

  公开号：

  US04691058A1

文献信息

• ISOSORBIDE-BASED POLYMETHACRYLATES
  申请人：Hillmyer Marc A.

  公开号：US20160229863A1

  公开（公告）日：2016-08-11

  A monomer comprises the structure wherein R 1 comprises H or a substituted hydrocarbyl or unsubstituted hydrocarbyl, and wherein R 2 comprises H, a halide, or a substituted or unsubstituted (C 1 -C 4 ) hydrocarbyl. A method comprises (a) reacting a dianhydrohexitol precursor having the structure with an acyl-group containing compound having the structure wherein R 1 comprises H or a substituted hydrocarbyl or unsubstituted hydrocarbyl, and X comprises a halide, a hydroxyl group, or an acyl group to form an acylated dianhydrohexitol ester intermediate having the structure and (b) reacting the acylated dianhydrohexitol ester intermediate with an acrylic-based compound having the structure wherein R 2 comprises H, a halide, or a substituted or unsubstituted (C 1 -C 4 ) hydrocarbyl, and Y comprises a halide, a hydroxyl group, or an acyl group, to form a dianhydrohexitol-based monomer having the structure

  一个单体包括结构，其中R1包括H或取代的烃基或未取代的烃基，R2包括H，卤素，或取代或未取代的（C1-C4）烃基。一种方法包括（a）将具有结构的二酮六醇前体与具有结构的含酰基化合物反应，其中R1包括H或取代的烃基或未取代的烃基，X包括卤素，羟基，或酰基，形成具有结构的酰化二酮六醇酯中间体，和（b）将酰化二酮六醇酯中间体与具有结构的丙烯基化合物反应，其中R2包括H，卤素，或取代或未取代的（C1-C4）烃基，Y包括卤素，羟基，或酰基，形成具有结构的二酮六醇基单体。
• MULTISTAGE PROCESS FOR PREPARING ALKALI METAL SALTS OF SPECIFIC 4-HYDROXY-2-OXO-2,5-DIHYDROFURAN-3-CARBOXYLIC ESTERS
  申请人：BAYER CROPSCIENCE AG

  公开号：US20150210662A1

  公开（公告）日：2015-07-30

  The present invention relates to a multi-stage method for preparing alkali metal salts of specific 4-hydroxy-2-oxo-2,5-dihydrofuran-3-carboxylic esters of the formula (I), in which M and R 1 are as defined in the description, which proceeds from malonic ester and does not require isolation of intermediates.

  本发明涉及一种多级方法，用于制备具有特定化学式(I)的4-羟基-2-氧代-2,5-二氢呋喃-3-羧酸酯的碱金属盐，其中M和R1如描述中定义，该方法从丙二酸酯开始，并且不需要分离中间体。
• PROCESS FOR PRODUCING POLYVALENT GLYCIDYL COMPOUND
  申请人：SHOWA DENKO K.K.

  公开号：US20170342042A1

  公开（公告）日：2017-11-30

  A polyvalent glycidyl compound is produced from a compound having one or more 2-alkenyl ether groups and two or more 2-alkenyl groups using a hydrogen peroxide aqueous solution as an oxidizing agent to oxidize the 2-alkenyl ether groups and the 2-alkenyl groups. A 2-alkenyl ether compound having two or more (un)substituted 2-alkenyl groups and one or more (un)substituted 2-alkenyl ether groups is oxidized using a hydrogen peroxide aqueous solution as an oxidizing agent in the presence of a tungsten compound and a quaternary ammonium salt as catalysts and of phosphoric acid as a co-catalyst, while controlling the pH of the reaction solution to 1.0-4.0 using an acid other than phosphoric acid. During the oxidation, the step of adding the hydrogen peroxide aqueous solution to the reaction solution and the step of adding the acid other than phosphoric acid thereto are alternately repeated at intervals two or more times.

  使用氢氧化物水溶液作为氧化剂，通过氧化2-烯基醚基团和2-烯基基团，从具有一个或多个2-烯基醚基团和两个或多个2-烯基基团的化合物中产生一种多价环氧化物化合物。在钨化合物和季铵盐作为催化剂和磷酸作为协同催化剂的存在下，在使用氢氧化物水溶液作为氧化剂的同时，氧化具有两个或更多个（未）取代的2-烯基基团和一个或多个（未）取代的2-烯基醚基团的2-烯基醚化合物，并使用除磷酸以外的酸将反应液的pH控制在1.0-4.0之间。在氧化过程中，将氢氧化物水溶液加入反应液和将酸加入其中的步骤交替重复两次或更多次的间隔时间内进行。
• Novel compounds having antiinflamatory activity: process for their preparation and pharmaceutical compositions containing them
  申请人：DR. REDDY'S LABORATORIES LTD.

  公开号：US20020032230A1

  公开（公告）日：2002-03-14

  The present invention relates to novel heterocyclic compounds of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their regioisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. 1

  本发明涉及一种新型杂环化合物，其一般式为（I），其衍生物，类似物，互变异构体，立体异构体，区域异构体，多晶形态，药学上可接受的盐，药学上可接受的溶剂化合物和药学上可接受的含有它们的组合物。
• [EN] PYRAZOLES HAVING ANTIINFLAMMATORY ACTIVITY<br/>[FR] PYRAZOLES PRESENTANT UNE ACTIVITE ANTI-INFLAMMATOIRE
  申请人：REDDY RESEARCH FOUNDATION

  公开号：WO2000066562A1

  公开（公告）日：2000-11-09

  The present invention relates to novel antiinflammatory compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their regioisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel heterocyclic compounds of general the formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their regioisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.

  本发明涉及新型抗炎化合物、它们的衍生物、类似物、互变异构体、立体异构体、区域异构体、多晶形态、药学上可接受的盐、药学上可接受的溶剂化合物以及含有它们的药学上可接受的组合物。更具体地说，本发明涉及一般式（I）的新型杂环化合物、它们的衍生物、类似物、互变异构体、立体异构体、区域异构体、多晶形态、药学上可接受的盐、药学上可接受的溶剂化合物以及含有它们的药学上可接受的组合物。