2-(α-Ethoxyvinyl)-pyridin | 62369-30-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-(α-Ethoxyvinyl)-pyridin
• 英文别名: 2-(1'-Ethoxyvinyl)-pyridin；2-(1-ethoxy-vinyl)-pyridine；Pyridine, 2-(1-ethoxyethenyl)-；2-(1-ethoxyethenyl)pyridine
• CAS: 62369-30-6
• 化学式: C₉H₁₁NO
• 分子量: 149.192
• InChiKey: KQMWACSLPZXSAB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(α-Ethoxyvinyl)-pyridin 以7%的产率得到
  参考文献：
  名称：

  TERENTEV P. B.; KOTOVA N. G.; KOST A. N., XIMIYA GETEROTSIKL. SOEDIN., 1978, HO 5, 651-655

  摘要：

  DOI：
• 作为产物：
  描述：

  2-乙烯基吡啶 以14%的产率得到
  参考文献：
  名称：

  TERENTEV P. B.; KOTOVA N. G., XIMIYA GETEROTSIKL. SOEDIN., 1978, HO 5, 647-650

  摘要：

  DOI：

文献信息

• ALKYNYL ALCOHOLS AND METHODS OF USE
  申请人：Genentech, Inc.

  公开号：US20150057260A1

  公开（公告）日：2015-02-26

  The invention relates to compounds of Formula (0): wherein A 1 -A 8 , R 4 and R 5 each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.

  该发明涉及具有以下结构的化合物（0）：其中A1-A8，R4和R5分别具有如本文所述的含义。 公式（0）的化合物及其药物组成物在治疗观察到NF-kB信号不受欢迎或过度激活的疾病和紊乱中是有用的。
• [EN] 5-(PYRIDIN-3-YL)OXAZOLE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR<br/>[FR] MODULATEURS ALLOSTÉRIQUES DE 5-(PYRIDIN-3-YL)OXAZOLE DU RÉCEPTEUR MUSCARINIQUE M4 DE L'ACÉTYLCHOLINE
  申请人：MERCK SHARP & DOHME

  公开号：WO2019000238A1

  公开（公告）日：2019-01-03

  Provided are 5-(pyridin-3-yl) oxazole compounds, the compositions comprising these compounds and the uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

  提供了含有5-(吡啶-3-基)噁唑化合物的组合物，这些化合物的组合物以及这些组合物在潜在预防或治疗M4肌胆碱受体参与的疾病中的用途。
• LUMINESCENCE ENHANCER
  申请人：FUJIREBIO INC.

  公开号：EP2028250A1

  公开（公告）日：2009-02-25

  An object of the present invention is to provide a luminescence enhancer by which a luminescence such as chemiluminescence can be enhanced with higher sensitivity and the luminescence can be continued over a prolonged period of time. That is, the present invention provides a luminescence enhancer containing a heteropolymer as an active ingredient, a method for measuring the luminescence using a luminescent substrate and said luminescence enhancer, and a method for analyzing a substance to be measured in a specimen wherein the specimen, an antigen and/or antibody corresponding to a substance to be measured, an antigen and/or antibody labeled-form with an activator and a luminescent substrate are reacted in the presence of said luminescence enhancer to measure the luminescence.

  本发明的目的是提供一种发光增强剂，通过它可以以更高的灵敏度增强化学发光等发光，并且发光可以持续很长时间。也就是说，本发明提供了一种含有杂聚合物作为活性成分的发光增强剂、一种使用发光底物和所述发光增强剂测量发光的方法，以及一种分析标本中待测物质的方法，其中标本、与待测物质相对应的抗原和/或抗体、抗原和/或抗体标记形式与活化剂和发光底物在所述发光增强剂的存在下反应以测量发光。
• LUMINESCENCE ENHANCER AND USE THEREOF
  申请人：Sugiyama Masami

  公开号：US20090081696A1

  公开（公告）日：2009-03-26

  An object of the present invention is to provide a luminescence enhancer by which a luminescence such as chemiluminescence can be enhanced with higher sensitivity and the luminescence can be continued over a prolonged period of time. That is, the present invention provides a luminescence enhancer containing a heteropolymer as an active ingredient, a method for measuring the luminescence using a luminescent substrate and said luminescence enhancer, and a method for analyzing a substance to be measured in a specimen wherein the specimen, an antigen and/or antibody corresponding to a substance to be measured, an antigen and/or antibody labeled-form with an activator and a luminescent substrate are reacted in the presence of said luminescence enhancer to measure the luminescence.
• SMALL-MOLECULE INHIBITORS OF PROTEIN SYNTHESIS INACTIVATING TOXINS
  申请人：Pang Yuan-Ping

  公开号：US20110263540A1

  公开（公告）日：2011-10-27

  Small-molecule inhibitors of a protein synthesis inhibiting toxin, e.g., ricin, abrin, Shiga, and Shiga-like toxins, as well as methods of using the inhibitors are provided. Further provided are methods of identifying small-molecule inhibitors of a protein synthesis inhibiting toxin.