3-Bromo-4-(chloromethyl)thiophene | 70260-08-1

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 芳基卤化物
• 英文名称: 3-Bromo-4-(chloromethyl)thiophene
• CAS: 70260-08-1
• 化学式: C₅H₄BrClS
• 分子量: 211.51
• InChiKey: YTFXBGFBUGEUCB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  28.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3-Bromo-4-(chloromethyl)thiophene 、 三苯基膦 以79%的产率得到
  参考文献：
  名称：

  GRONOWITZ S .; DAHLGREN T., CHEM. SER., 1977, 12, NO 2-3, 57-67

  摘要：

  DOI：

文献信息

• PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE
  申请人：Savira pharmaceuticals GmbH

  公开号：US20140194431A1

  公开（公告）日：2014-07-10

  The present invention relates to a compound having the general formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.

  本发明涉及具有通式（I）的化合物，可选地以药学上可接受的盐、溶剂合物、多型体、共药、共晶、前药、互变异构体、外消旋体、对映体或二对映体或其混合物的形式出现，这些化合物在治疗、缓解或预防病毒性疾病方面是有用的。此外，还披露了特定的联合疗法。
• [EN] PYRIDYLPHENYLAMINOQUINOLINES AND ANALOGUES<br/>[FR] PYRIDYLPHÉNYLAMINOQUINOLINES ET ANALOGUES
  申请人：BAYER AG

  公开号：WO2020079173A1

  公开（公告）日：2020-04-23

  The present disclosure relates to fungicidal active compounds, more specifically to pyridylphenylaminoquinolines and analogues thereof, processes and, intermediates for their preparation and use thereof as fungicidal active compound, particularly in the form of fungicide compositions. The present disclosure also relates to methods for the control of phytopathogenic fungi of plants using these compounds or compositions comprising thereof.

  本公开涉及杀真菌活性化合物，更具体地涉及吡啶基苯基氨基喹啉及其类似物，以及它们的制备过程和中间体，以及其作为杀真菌活性化合物的应用，特别是以杀菌剂组合物的形式。本公开还涉及使用这些化合物或包含它们的组合物控制植物病原真菌的方法。
• [EN] HETEROARYLAMINOQUINOLINES AND ANALOGUES<br/>[FR] HÉTÉROARYLAMINOQUINOLINES ET ANALOGUES
  申请人：BAYER AG

  公开号：WO2020079167A1

  公开（公告）日：2020-04-23

  The present disclosure relates to fungicidal active compounds, more specifically to heteroarylaminoquinolines and analogues thereof, processes and, intermediates for their preparation and use thereof as fungicidal active compound, particularly in the form of fungicide compositions. The present disclosure also relates to methods for the control of phytopathogenic fungi of plants using these compounds or compositions comprising thereof.

  本公开涉及杀真菌活性化合物，更具体地涉及杂环芳基氨基喹啉及其类似物，其制备的过程和中间体，以及它们作为杀真菌活性化合物的使用，特别是作为杀菌剂组合物的形式。本公开还涉及使用这些化合物或包含它们的组合物控制植物的植物病原真菌的方法。
• HETEROARYLAMINOQUINOLINES AND ANALOGUES
  申请人：Bayer Aktiengesellschaft

  公开号：US20210387964A1

  公开（公告）日：2021-12-16

  The present disclosure relates to fungicidal active compounds, more specifically to heteroarylaminoquinolines and analogues thereof, processes and, intermediates for their preparation and use thereof as fungicidal active compound, particularly in the form of fungicide compositions. The present disclosure also relates to methods for the control of phytopathogenic fungi of plants using these compounds or compositions comprising thereof.
• PYRIDYLPHENYLAMINOQUINOLINES AND ANALOGUES
  申请人：Bayer Aktiengesellschaft

  公开号：US20210386069A1

  公开（公告）日：2021-12-16

  The present disclosure relates to fungicidal active compounds, more specifically to pyridylphenylaminoquinolines and analogues thereof, processes and, intermediates for their preparation and use thereof as fungicidal active compound, particularly in the form of fungicide compositions. The present disclosure also relates to methods for the control of phytopathogenic fungi of plants using these compounds or compositions comprising thereof.