申请人:Kobelco Eco-Solutions Co., Ltd
公开号:EP3466932A1
公开(公告)日:2019-04-10
Developed is a technique according to which a nitrogen-containing bicyclic heterocyclic compound can be manufactured directly from nitrogen-containing heterocyclic compounds in a short period of time through a small number of steps without using expensive agents and a starting material that takes time and effort to synthesize. A method for manufacturing a nitrogen-containing bicyclic heterocyclic compound includes a synthesis step of synthesizing a nitrogen-containing bicyclic heterocyclic compound such as bipyrimidine, bipyrazine, or biquinoline by reacting, in a reaction solvent, one nitrogen-containing heterocyclic compound and another nitrogen-containing heterocyclic compound with a solution containing an alkali metal.
开发了一种技术,根据该技术,无需使用昂贵的制剂和费时费力合成的起始材料,只需通过少量步骤,即可在短时间内直接从含氮杂环化合物制造出含氮双环杂环化合物。一种制造含氮双环杂环化合物的方法包括一个合成步骤,即在反应溶剂中,将一种含氮杂环化合物和另一种含氮杂环化合物与含有碱金属的溶液反应,合成一种含氮双环杂环化合物,如双嘧啶、双吡嗪或双喹啉。