2-ethyl-3,4-tetramethylenepyrrole | 352199-39-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-ethyl-3,4-tetramethylenepyrrole
• 英文别名: 1-ethyl-4,5,6,7-tetrahydro-2H-isoindole
• CAS: 352199-39-4
• 化学式: C₁₀H₁₅N
• mdl: MFCD19220824
• 分子量: 149.236
• InChiKey: BJDIWMYMIKUJSN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  15.8
• 氢给体数：
  1
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  吡咯 、 1(4-methoxy-2,2'-bipyrrole-5-carboxaldehyde)(1.0 mmol) 、 2-ethyl-3,4-tetramethylenepyrrole 生成 4,5,6,7-Tetrahydro-3-((3-methoxy-5-(1H-pyrrol-2-yl)-2H-pyrrol-2-ylidene)methyl)-1-ethyl-2H-isoindole
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• IMAGING DENDRIMER NANOPROBES AND USES THEREOF
  申请人：Vinogradov Sergei A.

  公开号：US20110117020A1

  公开（公告）日：2011-05-19

  This invention relates to imaging nanoprobe and methods of use thereof. Specifically, the invention relates to long-lived oxygen-insensitive nanoprobe comprising a lumisescent moeity with a long excited state lifetime, embedded in a dendrimer, wherein said dendrimer is internally cross-linked and has hydrophilic peripheral layer.

  这项发明涉及成像纳米探针及其使用方法。具体而言，该发明涉及一种长寿命的氧不敏感纳米探针，包括一个具有长激发态寿命的发光基团，嵌入在一个树枝状聚合物中，所述树枝状聚合物内部交联，并具有亲水性外周层。
• Pyrrole-Type compounds, compositions, and methods for treating cancer or viral diseases
  申请人：Gemin X Biotechnologies Inc.

  公开号：US20040014987A1

  公开（公告）日：2004-01-22

  The present invention relates to novel Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a composition comprising a Pyrrole-Type compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell. The present invention also relates to novel Pyrrole-Type compounds, compositions, and methods useful for treating or preventing a viral infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the replication and/or infectivity of a virus.

  本发明涉及新型吡咯烷类化合物，包含吡咯烷类化合物的组合物，以及用于治疗或预防癌症或肿瘤性疾病的方法，包括给予含有吡咯烷类化合物的组合物。本发明的化合物、组合物和方法还可用于抑制癌细胞或肿瘤细胞的生长。本发明还涉及新型吡咯烷类化合物、组合物和用于治疗或预防病毒感染的方法。本发明的化合物、组合物和方法还可用于抑制病毒的复制和/或传染性。
• Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases
  申请人：——

  公开号：US20030009032A1

  公开（公告）日：2003-01-09

  The present invention relates to novel Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a composition comprising a Pyrrole-Type compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell. The present invention also relates to novel Pyrrole-Type compounds, compositions, and methods useful for treating or preventing a viral infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the replication and/or infectivity of a virus.

  本发明涉及一种新型吡咯类化合物，包含吡咯类化合物的组合物以及用于治疗或预防癌症或肿瘤性疾病的方法，其中包括给予包含吡咯类化合物的组合物。本发明的化合物、组合物和方法还可用于抑制癌细胞或肿瘤细胞的生长。本发明还涉及一种新型吡咯类化合物、组合物和方法，用于治疗或预防病毒感染。本发明的化合物、组合物和方法还可用于抑制病毒的复制和/或感染能力。
• Pyrrole-Type compounds, compositions and methods for treating cancer or viral disease
  申请人：Johnson A. Roy

  公开号：US20070037856A1

  公开（公告）日：2007-02-15

  The present invention relates to novel Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a composition comprising a Pyrrole-Type compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell. The present invention also relates to novel Pyrrole-Type compounds, compositions, and methods useful for treating or preventing a viral infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the replication and/or infectivity of a virus.

  本发明涉及新型吡咯类化合物、含有吡咯类化合物的组合物以及用于治疗或预防癌症或肿瘤性疾病的方法，包括给予含有吡咯类化合物的组合物。本发明的化合物、组合物和方法也可用于抑制癌细胞或肿瘤细胞的生长。本发明还涉及新型吡咯类化合物、组合物和方法，用于治疗或预防病毒感染。本发明的化合物、组合物和方法也可用于抑制病毒的复制和/或感染能力。
• Prodigiosin derivatives for treating cancer or viral diseases
  申请人：Gemin X Biotechnologies Inc.

  公开号：EP1431286A2

  公开（公告）日：2004-06-23

  The present invention relates to novel Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a composition comprising a Pyrrole-Type compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell. The present invention also relates to novel Pyrrole-Type compounds, compositions, and methods useful for treating or preventing a viral infection. The compounds, compositions, and methods of the invention are also useful for inhibiting the replication and/or infectivity of a virus.

  本发明涉及新型吡咯类化合物、包含吡咯类化合物的组合物，以及用于治疗或预防癌症或肿瘤性疾病的方法，其中包含施用包含吡咯类化合物的组合物。本发明的化合物、组合物和方法还可用于抑制癌细胞或肿瘤细胞的生长。本发明还涉及治疗或预防病毒感染的新型吡咯类化合物、组合物和方法。本发明的化合物、组合物和方法还可用于抑制病毒的复制和/或传染性。