1-phenyl-1-methyl-3-(2-succinimidoacetyl)cyclobutane | 646997-54-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-phenyl-1-methyl-3-(2-succinimidoacetyl)cyclobutane
• 英文别名: Agn-PC-0ndabu；1-[2-(3-methyl-3-phenylcyclobutyl)-2-oxoethyl]pyrrolidine-2,5-dione
• CAS: 646997-54-8
• 化学式: C₁₇H₁₉NO₃
• 分子量: 285.343
• InChiKey: NKGMGLOQJGMWJV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  54.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-phenyl-1-methyl-3-(2-succinimidoacetyl)cyclobutane 在 吡啶 、 盐酸羟胺 作用下， 以 乙醇 为溶剂， 反应 3.0h， 以85%的产率得到1-methyl-1-phenyl-3-[1-hydroxyimino-2-(succinimido)ethyl]cyclobutane
  参考文献：
  名称：

  Highly sensitive sensing of zinc(II) by development and characterization of a PVC-based fluorescent chemical sensor

  摘要：

  A sensor membrane with excellent performance based on 1-methyl-1-phenyl-3-[1-hydroxyimino-2-(succinimido)ethyl]cyclobutane has been developed for the determination of zinc(II) ions. The sensing membrane is capable of determining zinc(II) with an outstanding high selectivity over a dynamic range between 8.0 x 10(-8) and 1.6 x 10(-4) mol L(-1) with a limit of detection of 2.5 x 10(-8) mol L(-1)(1.6 mu g L(-1)). It can be easily and completely regenerated by using 0.1 mol L(-1) EDTA solution. The optical sensor developed here was found to be stable, cost effective, easy to prepare, and has unique selectivity towards Zn(2+) ion with respect to common metal ions. The proposed sensor was then applied for the determination of zinc in tap water and hair samples with satisfactory results. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2010.12.065

文献信息

• Highly sensitive sensing of zinc(II) by development and characterization of a PVC-based fluorescent chemical sensor
  作者：Nur Aksuner、Emur Henden、Berrin Yenigul、Ibrahim Yilmaz、Alaaddin Cukurovali

  DOI：10.1016/j.saa.2010.12.065

  日期：2011.3

  A sensor membrane with excellent performance based on 1-methyl-1-phenyl-3-[1-hydroxyimino-2-(succinimido)ethyl]cyclobutane has been developed for the determination of zinc(II) ions. The sensing membrane is capable of determining zinc(II) with an outstanding high selectivity over a dynamic range between 8.0 x 10(-8) and 1.6 x 10(-4) mol L(-1) with a limit of detection of 2.5 x 10(-8) mol L(-1)(1.6 mu g L(-1)). It can be easily and completely regenerated by using 0.1 mol L(-1) EDTA solution. The optical sensor developed here was found to be stable, cost effective, easy to prepare, and has unique selectivity towards Zn(2+) ion with respect to common metal ions. The proposed sensor was then applied for the determination of zinc in tap water and hair samples with satisfactory results. (C) 2010 Elsevier B.V. All rights reserved.