7-O-[[3,5-bis[6-[3-hydroxy-2-(hydroxymethyl)-2-methylpropoxy]carbonylhept-6-enoyloxymethyl]phenyl]methyl] 1-O-[3-hydroxy-2-(hydroxymethyl)-2-methylpropyl] 2-methylideneheptanedioate 、 (2,2,5-trimethyl-1,3-dioxan-5-yl)methyl 1-(iodomethyl)-2-oxocyclohexanecarboxylate 在
potassium carbonate 作用下,
反应 72.0h,
以44%的产率得到7-O-[2-[[7-[[3,5-bis[6-[2-methyl-3-[6-[(2,2,5-trimethyl-1,3-dioxan-5-yl)methoxycarbonyl]hept-6-enoyloxy]-2-[6-[(2,2,5-trimethyl-1,3-dioxan-5-yl)methoxycarbonyl]hept-6-enoyloxymethyl]propoxy]carbonylhept-6-enoyloxymethyl]phenyl]methoxy]-2-methylidene-7-oxoheptanoyl]oxymethyl]-2-methyl-3-[6-[(2,2,5-trimethyl-1,3-dioxan-5-yl)methoxycarbonyl]hept-6-enoyloxy]propyl] 1-O-[(2,2,5-trimethyl-1,3-dioxan-5-yl)methyl] 2-methylideneheptanedioate