2,6-Dimethyl-5,6-dihydro-thiazolo[3,2-b][1,2,4]triazole | 887604-96-8

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2,6-Dimethyl-5,6-dihydro-thiazolo[3,2-b][1,2,4]triazole
• 英文别名: 2,6-Dimethyl-5,6-dihydro[1,3]thiazolo[3,2-b][1,2,4]triazole；2,6-dimethyl-5,6-dihydro-[1,3]thiazolo[3,2-b][1,2,4]triazole
• CAS: 887604-96-8
• 化学式: C₆H₉N₃S
• 分子量: 155.224
• InChiKey: RDCOAHTVQCYVGD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  56
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-allylmercapto-3-methyl-1,2,4-triazole 在 硫酸 、 silica gel 作用下， 反应 0.13h， 生成 2,6-Dimethyl-5,6-dihydro-thiazolo[3,2-b][1,2,4]triazole
  参考文献：
  名称：

  Solvent Free Regioselective Cyclization of 3-Allylmercapto-1,2,4-Triazoles to Thiazolo[3,2-b]1,2,4-Triazoles Over Sulfuric Acid Adsorbed on Silica Gel

  摘要：

  3-mercapto-1,2,4-triazoles were condensed with allyl bromide in the presence of a base to afford the corresponding 3-allyl compounds 2. The latter were cyclized regioselectively to give 2,3-dihydro-3-methylthiazolo[3,2-b]1,2,4-triazoles 3.

  DOI：

  10.1080/104265091000624

文献信息

• SOLVENT FREE REGIOSELECTIVE HETEROCYCLIZATION OVER HZSM-5 ZEOLITE UNDER MICROWAVE IRRADIATION SYNTHESIS OF CONDENSED THIAZOLES
  作者：Majid M. Heravi、Majid M. Sadeghi、Mohammad Froomand、Shahnaz Khaleghi、Mitra Ghassemzadeh

  DOI：10.1515/hc.2006.12.3-4.195

  日期：2006.1
• Solvent Free Regioselective Cyclization of 3-Allylmercapto-1,2,4-Triazoles to Thiazolo[3,2-<i>b</i>]1,2,4-Triazoles Over Sulfuric Acid Adsorbed on Silica Gel
  作者：M. M. Heravi、H. R. Khademalfoghara、M. M. Sadeghi、Sh. Khaleghi、M. Ghassemzadeh

  DOI：10.1080/104265091000624

  日期：2006.2

  3-mercapto-1,2,4-triazoles were condensed with allyl bromide in the presence of a base to afford the corresponding 3-allyl compounds 2. The latter were cyclized regioselectively to give 2,3-dihydro-3-methylthiazolo[3,2-b]1,2,4-triazoles 3.