3-methylsulfonyl-5-(3,5-dimethylpiperidino)-1,2,4-thiadiazole | 850748-60-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 3-methylsulfonyl-5-(3,5-dimethylpiperidino)-1,2,4-thiadiazole
• 英文别名: 5-(3,5-dimethylpiperidin-1-yl)-3-methylsulfonyl-1,2,4-thiadiazole
• CAS: 850748-60-6
• 化学式: C₁₀H₁₇N₃O₂S₂
• 分子量: 275.396
• InChiKey: UZQGHGJNPWJBEP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  99.8
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  3-methylsulfonyl-5-(3,5-dimethylpiperidino)-1,2,4-thiadiazole 、 3-戊炔-2-醇 在 sodium hydride 作用下， 以 DMF (N,N-dimethyl-formamide) 为溶剂， 反应 2.25h， 生成 3-(1-methyl-2-butynyloxy)-5-(3,5-dimethylpiperidino)-1,2,4-thiadiazole
  参考文献：
  名称：

  [EN] 1,2,4-THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME
  [FR] COMPOSES 1,2,4-THIADIAZOLE ET COMPOSITION DE LUTTE ANTIPARASITAIRE CONTENANT CES COMPOSES

  摘要：

  公开号：

  WO2005037805A3
• 作为产物：
  描述：

  3-methylthio-5-(3,5-dimethylpiperidino)-1,2,4-thiadiazole 在 间氯过氧苯甲酸 作用下， 以 氯仿 为溶剂， 反应 18.0h， 生成 3-methylsulfinyl-5-(3,5-dimethylpiperidino)-1,2,4-thiadiazole 、 3-methylsulfonyl-5-(3,5-dimethylpiperidino)-1,2,4-thiadiazole
  参考文献：
  名称：

  [EN] 1,2,4-THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME
  [FR] COMPOSES 1,2,4-THIADIAZOLE ET COMPOSITION DE LUTTE ANTIPARASITAIRE CONTENANT CES COMPOSES

  摘要：

  公开号：

  WO2005037805A3

文献信息

• 1,2,4-Thiadazole compounds and use thereof
  申请人：Hara Hideki

  公开号：US20070004722A1

  公开（公告）日：2007-01-04

  The present invention relates to a 1,2,4-thiadiazole compound of the formula (I) represented by the formula (1): wherein R 1? represents C3-C7 alkynyl and X represents C4-C7 straight alkylene optionally substituted with one to four of R 2?, C4-C7 straight alkenylene optionally substituted with one to four of R 2?, ethylene-oxy-ethylene optionally substituted with one to four of R 4?, or ethylene-thio-ethylene optionally substituted with one to four of R 4?, R 2? represents a halogen atom, trifluoromethyl or C1-C4 alkyl, and R4 represents a fluorine atom or C1-C3 alkyl. The 1,2,4-thiadiazole compound has an excellent pests controlling activity, and can effectively control an pests such as insect pests, acarine pests and the like.

  本发明涉及一种由式（1）表示的式（I）的1,2,4-噻二唑化合物，其中R1?代表C3-C7炔基，X代表C4-C7直链烷基，可选地用一到四个R2?，C4-C7直链烯基，可选地用一到四个R2?，乙二醇基乙二醇，可选地用一到四个R4?，或者乙硫基乙二醇，可选地用一到四个R4?取代，R2?代表卤素原子、三氟甲基或C1-C4烷基，R4代表氟原子或C1-C3烷基。该1,2,4-噻二唑化合物具有优异的害虫控制活性，可以有效地控制昆虫害虫、螨虫等害虫。
• 1,2,4-Thiadiazole compounds and pests controlling composition containing the same
  申请人：Sumitomo Chemical Company Limited

  公开号：US07371746B2

  公开（公告）日：2008-05-13

  The present invention relates to a 1,2,4-thiadiazole compound of the formula (I) represented by the formula (1): wherein R1? represents C3-C7 alkynyl and X represents C4-C7 straight alkylene optionally substituted with one to four of R2?, C4-C7 straight alkenylene optionally substituted with one to four of R2?, ethylene-oxy-ethylene optionally substituted with one to four of R4?, or ethylene-thio-ethylene optionally substituted with one to four of R4?, R2? represents a halogen atom, trifluoromethyl or C1-C4 alkyl, and R4 represents a fluorine atom or C1-C3 alkyl. The 1,2,4-thiadiazole compound has an excellent pests controlling activity, and can effectively control an pests such as insect pests, acarine pests and the like

  本发明涉及一种1,2,4-噻二唑化合物，其化学式（I）由式（1）表示：其中R1?表示C3-C7炔基，X表示C4-C7直链烷基，可选择地用R2?的1-4个取代基取代，或C4-C7直链烯基，可选择地用R2?的1-4个取代基取代，乙二醇基乙二醚，可选择地用R4?的1-4个取代基取代，或乙二醇基硫乙烷，可选择地用R4?的1-4个取代基取代，R2?表示卤素原子，三氟甲基或C1-C4烷基，R4表示氟原子或C1-C3烷基。该1,2,4-噻二唑化合物具有优异的害虫控制活性，可以有效地控制害虫，如昆虫害虫，螨虫等。
• 1,2,4-Thiadiazole Compounds and Pests Controlling Composition Containing the same
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP2492265A1

  公开（公告）日：2012-08-29

  The present invention relates to a 1,2,4-thiadiazole compound of the formula (I): wherein R1 represents C3-C7 alkynyl; X represents C4-C7 straight alkylene optionally substituted with one to four of R2, C4-C7 straight alkenylene optionally substituted with one to four of R2, or ethylene-thioethylene optionally substituted with one to four of R4; R2 represents a halogen atom, trifluoromethyl or C1-C4 alkyl; and R4 represents a fluorine atom or C1-C3 alkyl. The 1,2,4-thiadiazole compound has an excellent pest controlling activity, and can effectively control pests such as insect pests, acarine pests and the like.

  本发明涉及一种式（I）的 1，2，4-噻二唑化合物： 其中 R1 代表 C3-C7 烷基；X 代表任选被 R2 的 1 至 4 个取代的 C4-C7 直烯基、任选被 R2 的 1 至 4 个取代的 C4-C7 直烯基或任选被 R4 的 1 至 4 个取代的乙烯-硫代乙烯基；R2 代表卤原子、三氟甲基或 C1-C4 烷基；R4 代表氟原子或 C1-C3 烷基。1,2,4-噻二唑化合物具有极佳的害虫防治活性，可有效防治害虫，如昆虫、螨类害虫等。
• 1,2,4- THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1765798A2

  公开（公告）日：2007-03-28
• US7371746B2
  申请人：——

  公开号：US7371746B2

  公开（公告）日：2008-05-13