1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid (4'-chloro-2'-fluoro-5'-methylbiphenyl-2-yl)-amide | 907204-25-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid (4'-chloro-2'-fluoro-5'-methylbiphenyl-2-yl)-amide
• 英文别名: N-(2'-fluoro-4'-chloro-5'-methylbiphenyl-2-yl)-3-trifluoromethyl-1-methyl-1H-pyrazole-4-carboxamide；N-(2'-fluoro-4'-chloro-5'-methyl-biphenyl-2-yl)-1-methyl-3-trifluoro-methyl-1H-pyrazole-4 carboxamide；N-(2'-fluoro-4'-chloro-5'-methylbiphenyl-2-yl)-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide；N-[2-(4-chloro-2-fluoro-5-methylphenyl)phenyl]-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxamide
• CAS: 907204-25-5
• 化学式: C₁₉H₁₄ClF₄N₃O
• 分子量: 411.786
• InChiKey: ILKDFYNYRDQIQC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  28
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  46.9
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid (3',4',5'-trifluorobiphenyl-2-yl)-amide 、 氟苯吡菌胺 、 1-methyl-3-difluoromethyl-1H-pyrazole-4-carboxylic acid (2',4',5'-trifluorobiphenyl-2-yl)-amide 、 N-(3',4',5'-trifluorobiphenyl-2-yl)-3-chlorofluoromethyl-1-methyl-1H-pyrazole-4-carboxamide 、 N-[2-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 、 3-(difluoromethyl)-1-methyl-N-[2-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-1H-pyrazole-4-carboxamide 、 N-[2-(2-chloro-1,1,2-trifluoroethoxy)phenyl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 、 n-[2-(2-Chlor-1,1,2-trifluoroethoxy)phenyl]-3-difluoromethyl-1-methyl-1h-pyrazole-4-carboxamide 、 3-(difluoromethyl)-1-methyl-N-[2-(1,1,2,2-tetrafluoroethoxy)phenyl]-1H-pyrazol-4-carboxamide 、 N-[2-(1,1,2,2-tetrafluoroethoxy)phenyl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 、 N-(4'-(trifluoromethylthio)biphenyl-2-yl)-3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxamide 、 N-(4'-(trifluoromethylthio)biphenyl-2-yl)-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide 生成 1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid (4'-chloro-2'-fluoro-5'-methylbiphenyl-2-yl)-amide
  参考文献：
  名称：

  Fungicidal Mixtures

  摘要：

  本发明涉及混合物，包括以下活性成分：1）式（I）的杀真菌化合物，其中：R1是烷基；烷氧基烷基；卤代烷基；芳基烷基；芳基；或杂环芳基；R2是烷基；烷氧基烷基；卤代烷基；芳基烷基；芳基；杂环芳基；5-嘧啶基；或2-或5-噻唑基；R3是H；烷基；烷氧基烷基；卤代烷基；芳基烷基；芳氧基烷基；芳硫基烷基；芳基；杂环芳基；或烷基硅基；R4是H；酰基；卤代酰基；烷氧羰基；芳基氧羰基；烷基氨基羰基；或二烷基氨基羰基；或其盐；以及2）从咪唑类，斯特罗比林，卡波酰胺，杂环化合物，氨基甲酸酯和其他活性化合物中选择的杀真菌化合物II，以协同有效量混合。

  公开号：

  US20100179059A1

文献信息

• Pyrazolecarboxanilides, Process for Their Preparation and Compositions Comprising Them for Controlling Harmful Fungi
  申请人：Gewehr Markus

  公开号：US20080153707A1

  公开（公告）日：2008-06-26

  The present invention relates to pyrazolecarboxanilides I in which the variables are as defined below: n is zero or 2; m is 2 or 3; X 1 is fluorine or chlorine; X 2 is halogen; Y is CN, NO 2 , C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, methoxy or methylthio; p is zero or 1; R 1 is fluorine, chlorine, bromine, C 1 -C 4 -alkyl or C 1 -C 4 -haloalkyl; R 2 is hydrogen or halogen; R 3 is hydrogen, methyl or ethyl; W is O or S; with the proviso that, if a) W═O, R 1 =methyl and R 3 is hydrogen, R 2 is not fluorine, or b) W═O, n=0, m=2, p=0, R 2 and R 3 are hydrogen, R 1 is not trifluoromethyl or difluoromethyl, to processes for preparing these compounds, to compositions comprising them and to methods for using them for controlling harmful fungi.

  本发明涉及吡唑羧酰胺I，其中变量定义如下：n为零或2；m为2或3；X1为氟或氯；X2为卤素；Y为CN，NO2，C1-C4-烷基，C1-C4-卤代烷基，甲氧基或甲硫基；p为零或1；R1为氟，氯，溴，C1-C4-烷基或C1-C4-卤代烷基；R2为氢或卤素；R3为氢，甲基或乙基；W为O或S；前提是，如果a）W═O，R1=甲基且R3为氢，R2不为氟，或b）W═O，n=0，m=2，p=0，R2和R3为氢，R1不为三氟甲基或二氟甲基，则本发明还涉及制备这些化合物的方法，包括它们的组合物以及用于控制有害真菌的方法。
• Azolylmethyloxiranes, use Thereof and Agents Containing the Same
  申请人：Dietz Jochen

  公开号：US20100273651A1

  公开（公告）日：2010-10-28

  The present invention relates to azolylmethyloxiranes of the formula I in which the variables A, B and D have the meanings as defined in the description and the claims.

  本发明涉及式I的氮杂环甲基环氧烷，其中变量A、B和D的含义如描述和权利要求所定义。
• Combinations comprising a fungicidal strain and at least one additional fungicide
  申请人：BASF SE

  公开号：EP2292098A1

  公开（公告）日：2011-03-09

  Fungicidal mixtures, comprising 1) a fungicidal Bacillus substilis strain with NRRL Accession No. B-21661, or a mutant of these strains having all the identifying characteristics of the respective strain, or a metabolite produced by the respective strain that exhibits activity against plant pathogenic fungi, and 2) at least one chemical compound II, selected from the active carboxamides; in a synergistically effective amount, methods for controlling harmful fungi using compositions of components 1) and 2), the use of a component 1) with a component 2) for preparing such compositions, and also fungicidal agents and seed comprising such compositions.

  杀真菌混合物，包括 1) NRRL 编号为 B-21661 的杀真菌枯草芽孢杆菌（Bacillus substilis）菌株，或具有相应菌株所有识别特征的突变体，或由相应菌株产生的对植物病原真菌具有活性的代谢物、 和 2) 至少一种选自活性羧酰胺的化合物 II； 以增效有效量使用成分 1) 和 2) 组合物控制有害真菌的方法、使用成分 1) 和成分 2) 制备此类组合物的方法，以及包含此类组合物的杀真菌剂和种子。
• Pesticidal mixtures comprising an anthranilamide insecticide and a carboxamide fungicide
  申请人：BASF SE

  公开号：EP2489264A2

  公开（公告）日：2012-08-22

  Pesticidal mixtures comprising, as active components, 1) an anthranilamid compound of the formula I wherein the variables are defined according to the description, and 2) at least one fungicidal compound II selected from the group of carboxamides as defined in the description; in a synergistically effective amount, methods for controlling pests, and harmful fungi, methods of protecting plants from attack or infestation by insects, acarids or nematodes, methods for treating, controlling, preventing or protecting an animal against infestation or infection by parasites, compositions containing these mixtures, and methods for their preparation.

  杀虫混合物，其活性成分包括 1) 式 I 的蒽酰胺化合物 其中变量根据说明定义，以及 2) 至少一种选自描述中定义的羧酰胺类的杀真菌化合物 II； 以增效有效的量，控制害虫和有害真菌的方法，保护植物免受昆虫、螨虫或线虫攻击或侵扰的方法，治疗、控制、预防或保护动物免受寄生虫侵扰或感染的方法，含有这些混合物的组合物及其制备方法。
• Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide
  申请人：BASF SE

  公开号：EP2489262A2

  公开（公告）日：2012-08-22

  Pesticidal mixtures comprising, as active components, 1) an anthranilamid compound of the formula I wherein the variables are defined according to the description, and 2) at least one fungicidal compound II which is: N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-difluoromethyl-1-methylpyrazole-4-carboxamide; in a synergistically effective amount, methods for controlling pests, and harmful fungi, methods of protecting plants from attack or infestation by insects, acarids or nematodes, methods for treating, controlling, preventing or protecting an animal against infestation or infection by parasites, compositions containing these mixtures, and methods for their preparation.

  杀虫混合物，其活性成分包括 1) 式 I 的蒽酰胺化合物 其中变量的定义见说明，以及 2) 至少一种杀真菌化合物 II，它是 N-(3',4'-二氯-5-氟联苯-2-基)-3-二氟甲基-1-甲基吡唑-4-甲酰胺； 以协同增效的有效量，控制害虫和有害真菌的方法，保护植物免受昆虫、害虫或线虫攻击或侵扰的方法，治疗、控制、预防或保护动物免受寄生虫侵扰或感染的方法，含有这些混合物的组合物及其制备方法。