2-[[6-[[2-(1,3-Benzothiazol-2-yl)phenoxy]methyl]pyridin-2-yl]methyl-(pyridin-2-ylmethyl)amino]ethanol | 1414968-70-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 2-[[6-[[2-(1,3-Benzothiazol-2-yl)phenoxy]methyl]pyridin-2-yl]methyl-(pyridin-2-ylmethyl)amino]ethanol
• 英文别名: 2-[[6-[[2-(1,3-benzothiazol-2-yl)phenoxy]methyl]pyridin-2-yl]methyl-(pyridin-2-ylmethyl)amino]ethanol
• CAS: 1414968-70-9
• 化学式: C₂₈H₂₆N₄O₂S
• 分子量: 482.606
• InChiKey: IWVRDRMPVSSKQU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  35
• 可旋转键数：
  10
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  99.6
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  2-(2-羟基苯基)苯并噻唑 、 2-[[6-(Chloromethyl)pyridin-2-yl]methyl-(pyridin-2-ylmethyl)amino]ethanol 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以88%的产率得到2-[[6-[[2-(1,3-Benzothiazol-2-yl)phenoxy]methyl]pyridin-2-yl]methyl-(pyridin-2-ylmethyl)amino]ethanol
  参考文献：
  名称：

  Reactive Probes for Ratiometric Detection of Co²⁺ and Cu⁺ Based on Excited-State Intramolecular Proton Transfer Mechanism

  摘要：

  An excited-state intramolecular proton transfer (ESIPT) mechanism based two reactive probes HBTCo and HBTCu is reported for the selective detection of Co2+ and Cu+ respectively in a reducing aqueous environment. Co2+ and Cu+ mediated oxidative benzylic ether (C-O) bond cleavage offers ratiometric detection of these metal ions.

  DOI：

  10.1021/ol302904c

文献信息

• Reactive Probes for Ratiometric Detection of Co²⁺ and Cu⁺ Based on Excited-State Intramolecular Proton Transfer Mechanism
  作者：Debabrata Maity、Vikash Kumar、T. Govindaraju

  DOI：10.1021/ol302904c

  日期：2012.12.7

  An excited-state intramolecular proton transfer (ESIPT) mechanism based two reactive probes HBTCo and HBTCu is reported for the selective detection of Co2+ and Cu+ respectively in a reducing aqueous environment. Co2+ and Cu+ mediated oxidative benzylic ether (C-O) bond cleavage offers ratiometric detection of these metal ions.